LOCUS AF104253 1803 bp mRNA linear HUM 04-FEB-1999
DEFINITION Homo sapiens transcriptional co-activator CRSP70 (CRSP70) mRNA,
complete cds.
ACCESSION AF104253
VERSION AF104253.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1803)
AUTHORS Ryu,S., Zhou,S., Ladurner,A.G. and Tjian,R.
TITLE The transcriptional cofactor complex CRSP is required for activity
of the enhancer-binding protein Sp1
JOURNAL Nature 397 (6718), 446-450 (1999)
PUBMED 9989412
REFERENCE 2 (bases 1 to 1803)
AUTHORS Ryu,S., Zhou,S., Ladurner,A.G. and Tjian,R.
TITLE Direct Submission
JOURNAL Submitted (05-NOV-1998) Dept. of Molecular and Cell Biology, Howard
Hughes Medical Institute, University of California at Berkeley, 401
Barker Hall, Berkeley, CA 94720-3204, USA
FEATURES Location/Qualifiers
source 1..1803
/db_xref="H-InvDB:HIT000069412"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1803
/gene="CRSP70"
CDS 1..1803
/gene="CRSP70"
/function="required for Sp1 activation"
/note="similar N-terminal to that of TFIIS and elongin A"
/codon_start=1
/product="transcriptional co-activator CRSP70"
/protein_id="AAD12722.1"
/translation="MTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPIT
KEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEAALRGLAGATG
SANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDFGHPG
PPPKVSKASHDPLVPNSSPLPTNGISGSPESFASSLDGSGHAGPEGSRLERDENDKHS
GKIPVNAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPR
NSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPS
AESPVCWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSK
KKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVH
MEQQSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAH
HFMSEYLKQEESTRQGARQLHVLVPQSPPTDLPGLTREVTQDDLDRIQASQWPGVNGC
QDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD"
BASE COUNT 388 a 601 c 566 g 248 t
ORIGIN
1 atgacagcgg ctccggcgtc tccgcagcag atcagggacc ggctgctgca ggccatcgac
61 ccccagagca acatccggaa catggtggcg gtgctggaag tcatctccag cctggagaaa
121 taccctatta ccaaagaggc acttgaggaa acacgacttg ggaagctcat caacgacgtc
181 cgcaagaaaa ccaagaacga ggagctcgcc aagcgggcca agaagctgct gcggagctgg
241 cagaagctca tcgagccggc acaccagcat gaggcggcgc tgcgggggct ggcgggggcc
301 accggctctg ccaacggggg cgcacacaac tgccggccgg aggtgggggc ggctggccca
361 cccaggagca tccatgacct gaagagccgc aatgacctcc agaggctgcc cgggcagcgg
421 ctggacaggc tgggcagccg caagcgccgg ggtgaccagc gtgacttcgg ccacccaggg
481 ccgccaccca aggtctccaa agctagccac gaccccctgg tccccaactc atcccccctc
541 cccaccaacg ggatcagtgg gagtccagag agcttcgcca gctccctgga tggcagtggg
601 catgcaggcc cagagggcag ccgcctggag cgtgacgaga atgacaagca cagtggcaag
661 atccccgtca acgccgtgcg accgcacacc agctccccgg gcctgggcaa gccccctgga
721 ccctgcttgc agccaaaggc ttcggtgctg cagcagctgg acagggtgga cgagactccg
781 gggcctcccc atcccaaggg accccctcgc tgctctttca gtcctcggaa ctcacggcat
841 gagggctcct ttgcccggca gcagagcttg tatgcaccca agggctccgt gcccagcccc
901 tcaccgcggc cccaggcact cgatgccaca caggtgccgt caccgcttcc actggcacag
961 ccgtccacac cccccgtacg gcggctcgag ctgctgccca gtgcggaaag cccagtgtgc
1021 tggcttgagc agcctgagag ccaccagcgg ctggcggggc cgggctgcaa ggcagggctg
1081 tccccagccg agcccctcct gtcccgggca ggcttttccc cagactcctc caaggcggac
1141 agtgatgctg cctcctcagg gggctcggac agtaaaaaga agaagaggta ccgacctcga
1201 gactatacgg ttaacttgga cgggcaggtg gctgaggcgg gcgtcaagcc tgtccggtta
1261 aaagagcgga agctcacctt tgaccccatg acgagacaga tcaaacctct gacccagaaa
1321 gagccagtgc gggcagacag ccctgtgcac atggagcagc agtccaggac agagctggac
1381 aagcaggagg ccaaggccag cctccagagc cccttcgaac agacgaactg gaaggagctg
1441 tcacgcaacg agatcatcca gtcctacctg agccggcaga gcagcctgct ctcatcatcg
1501 ggcgcgcaga ccccaggggc tcaccacttc atgtctgagt acctgaagca ggaggagagc
1561 acccggcaag gggccaggca gctgcatgtg ctggtgcctc aaagcccgcc cacggacctc
1621 cctggtctga cccgggaggt cacacaggac gatctcgaca gaatccaggc cagccagtgg
1681 ccgggggtga acgggtgtca ggacacacag ggtaactggt atgactggac gcagtgcata
1741 tcgctcgatc cgcacggcga cgacgggcgc ttgaacattc tgccttatgt ctgcttggac
1801 tga
//