LOCUS AF104032 4670 bp mRNA linear HUM 17-MAR-1999
DEFINITION Homo sapiens L-type amino acid transporter subunit LAT1 mRNA,
complete cds.
ACCESSION AF104032
VERSION AF104032.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4670)
AUTHORS Prasad,P.D., Wang,H., Huang,W., Kekuda,R., Rajan,D.P., Leibach,F.H.
and Ganapathy,V.
TITLE Human LAT1, a subunit of system L amino acid transporter: molecular
cloning and transport function
JOURNAL Biochem. Biophys. Res. Commun. 255 (2), 283-288 (1999)
PUBMED 10049700
REFERENCE 2 (bases 1 to 4670)
AUTHORS Prasad,P.D., Wang,H., Huang,W., Kekuda,R., Rajan,D.P., Leibach,F.H.
and Ganapathy,V.
TITLE Direct Submission
JOURNAL Submitted (02-NOV-1998) Obstetrics and Gynecology, Medical College
of Georgia, 1120 15th Street, Augusta, GA 30912, USA
FEATURES Location/Qualifiers
source 1..4670
/db_xref="H-InvDB:HIT000069405"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
CDS 67..1590
/function="transports large neutral amino acids in
association with 4F2HC antigen"
/note="LAT1"
/codon_start=1
/product="L-type amino acid transporter subunit LAT1"
/protein_id="AAD20464.1"
/translation="MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGV
TLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALC
YAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPL
FPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQ
IGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPL
AIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS
CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKD
IFSVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVS
FWKTPVECGIGFTIILSGLPVYFFGVWWKNKPKWLLQGIFSTTVLCQKLMQVVPQET"
BASE COUNT 896 a 1471 c 1301 g 1002 t
ORIGIN
1 gcggcgcgca cactgctcgc tgggccgcgg ctcccgggtg tcccaggccc ggccggtgcg
61 cagagcatgg cgggtgcggg cccgaagcgg cgcgcgctag cggcgccggc ggccgaggag
121 aaggaagagg cgcgggagaa gatgctggcc gccaagagcg cggacggctc ggcgccggca
181 ggcgagggcg agggcgtgac cctgcagcgg aacatcacgc tgctcaacgg cgtggccatc
241 atcgtgggga ccattatcgg ctcgggcatc ttcgtgacgc ccacgggcgt gctcaaggag
301 gcaggctcgc cggggctggc gctggtggtg tgggccgcgt gcggcgtctt ctccatcgtg
361 ggcgcgctct gctacgcgga gctcggcacc accatctcca aatcgggcgg cgactacgcc
421 tacatgctgg aggtctacgg ctcgctgccc gccttcctca agctctggat cgagctgctc
481 atcatccggc cttcatcgca gtacatcgtg gccctggtct tcgccaccta cctgctcaag
541 ccgctcttcc ccacctgccc ggtgcccgag gaggcagcca agctcgtggc ctgcctctgc
601 gtgctgctgc tcacggccgt gaactgctac agcgtgaagg ccgccacccg ggtccaggat
661 gcctttgccg ccgccaagct cctggccctg gccctgatca tcctgctggg cttcgtccag
721 atcgggaagg gtgatgtgtc caatctagat cccaacttct catttgaagg caccaaactg
781 gatgtgggga acattgtgct ggcattatac agcggcctct ttgcctatgg aggatggaat
841 tacttgaatt tcgtcacaga ggaaatgatc aacccctaca gaaacctgcc cctggccatc
901 atcatctccc tgcccatcgt gacgctggtg tacgtgctga ccaacctggc ctacttcacc
961 accctgtcca ccgagcagat gctgtcgtcc gaggccgtgg ccgtggactt cgggaactat
1021 cacctgggcg tcatgtcctg gatcatcccc gtcttcgtgg gcctgtcctg cttcggctcc
1081 gtcaatgggt ccctgttcac atcctccagg ctcttcttcg tggggtcccg ggaaggccac
1141 ctgccctcca tcctctccat gatccaccca cagctcctca cccccgtgcc gtccctcgtg
1201 ttcacgtgtg tgatgacgct gctctacgcc ttctccaagg acatcttctc cgtcatcaac
1261 ttcttcagct tcttcaactg gctctgcgtg gccctggcca tcatcggcat gatctggctg
1321 cgccacagaa agcctgagct tgagcggccc atcaaggtga acctggccct gcctgtgttc
1381 ttcatcctgg cctgcctctt cctgatcgcc gtctccttct ggaagacacc cgtggagtgt
1441 ggcatcggct tcaccatcat cctcagcggg ctgcccgtct acttcttcgg ggtctggtgg
1501 aaaaacaagc ccaagtggct cctccagggc atcttctcca cgaccgtcct gtgtcagaag
1561 ctcatgcagg tggtccccca ggagacatag ccaggaggcc gagtggctgc cggaggagca
1621 tgcgcagagg ccagttaaag tagatcacct cctcgaaccc actccggttc cccgcaaccc
1681 acagctcagc tgcccatccc agtccctcgc cgtccctccc aggtcgggca gtggaggctg
1741 ctgtgaaaac tctggtacga atctcatccc tcaactgagg gccagggacc caggtgtgcc
1801 tgtgctcctg cccaggagca gcttttggtc tccttgggcc ctttttccct tccctccttt
1861 gtttacttat atatatattt tttttaaact taaattttgg gtcaacttga caccactaag
1921 atgatttttt aaggagctgg gggaaggcag gagccttcct ttctcctgcc ccaagggccc
1981 agaccctggg caaacagagc tactgagact tggaacctca ttgctacgac agacttgcac
2041 tgaagccgga cagctgccca gacacatggg cttgtgacat tcgtgaaaac caaccctgtg
2101 ggcttatgtc tctgccttag ggtttgcaga gtggaaactc agccgtaggg tggcactggg
2161 agggggtggg ggatctgggc aaggtgggtg attcctctca ggaggtgctt gaggccccga
2221 tggactcctg accataatcc tagccctgag acaccatcct gagccaggga acagccccag
2281 ggttgggggg tgccggcatc tcccctagct caccaggcct ggcctctggg cagtgtggcc
2341 tcttggctat ttctgtgtcc agttttggag gctgagttct ggttcatgca gacaaagccc
2401 tgtccttcag tcttctagaa acagagacaa gaaaggcaga cacaccgcgg ccaggcaccc
2461 atgtgggcgc ccaccctggg ctccacacag cagtgtcccc tgccccagag gtcgcagcta
2521 ccctcagcct ccaatgcatt ggcctctgta ccgcccggca gccccttctg gccggtgctg
2581 ggttcccact cccggcctag gcacctcccc gctctccctg tcacgctcat gtcctgtcct
2641 ggtcctgatg cccgttgtct aggagacaga gccaagcact gctcacgtct ctgccgcctg
2701 cgtttggagg cccctgggct ctcacccagt ccccacccgc ctgcagagag ggaactaggg
2761 caccccttgt ttctgttgtt cccgtgaatt tttttcgcta tgggaggcag ccgaggcctg
2821 gccaatgcgg cccactttcc tgagctgtcg ctgcctccat ggcagcagcc aaggaccccc
2881 agaacaagaa gacccccccg caggatccct cctgagctcg gggggctctg ccttctcagg
2941 ccccgggctt cccttctccc cagccagagg tggagccaag tggtccagcg tcactccagt
3001 gctcagctgt ggctggagga gctggcctgt ggcacagccc tgagtgtccc aagccgggag
3061 ccaacgaagc cggacacggc ttcactgacc agcggctgct caagccgcaa gctctcagca
3121 agtgcccagc ggagcctgcc gcccccacct gggcaccggg accccctcac catccagtgg
3181 gcccggagaa acctgatgaa cagtttgggg actcaggacc agatgtccgt ctctcttgct
3241 tgaggaatga agacctttat tcacccctgc cccgttgctt cccgctgcac atggacagac
3301 ttcacagcgt ctgctcatag gacctgcatc cttcctgggg acgaattcca ctcgtccaag
3361 ggacagccca cggtctggag gccgaggacc accagcaggc aggtggactg actgtgttgg
3421 gcaagacctc ttccctctgg gcctgttctc ttggctgcaa ataaggacag cagctggtgc
3481 cccacctgcc tggtgcattg ctgtgtgaat ccaggaggca gtggacatcg taggcagcca
3541 cggccccggg tccaggagaa gtgctccctg gaggcacgca ccactgcttc ccactggggc
3601 cggcggggcc cacgcacgac gtcagcctct taccttcccg cctcggctag gggtcctcgg
3661 gatgccgttc tgttccaacc tcctgctctg ggacgtggac atgcctcaag gatacaggga
3721 gccggcggcc tctcgacggc acgcacttgc ctgttggctg ctgcggctgt gggcgagcat
3781 gggggctgcc agcgtctgtt gtggaaagta gctgctagtg aaatggctgg ggccgctggg
3841 gtccgtcttc acactgcgca ggtctcttct gggcgtctga gctggggtgg gagctcctcc
3901 gcagaaggtt ggtggggggt ccagtctgtg atccttggtg ctgtgtgccc cactccagcc
3961 tggggacccc acttcagaag gtaggggccg tgtcccgcgg tgctgactga ggcctgcttc
4021 cccctccccc tcctgctgtg ctggaattcc acagggacca gggccaccgc aggggactgt
4081 ctcagaagac ttgatttttc cgtccctttt tctccacact ccactgacaa acgtccccag
4141 cggtttccac ttgtgggctt caggtgtttt caagcacaac ccaccacaac aagcaagtgc
4201 attttcagtc gttgtgcttt tttgttttgt gctaacgtct tactaattta aagatgctgt
4261 cggcaccatg tttatttatt tccagtggtc atgctcagcc ttgctgctct gcgtggcgca
4321 ggtgccatgc ctgctccctg tctgtgtccc agccacgcag ggccatccac tgtgacgtcg
4381 gccgaccagg ctggacaccc tctgccgagt aatgacgtgt gtggctggga ccttctttat
4441 tctgtgttaa tggctaacct gttacactgg gctgggttgg gtagggtgtt ctggcttttt
4501 tgtggggttt ttatttttaa agaaacactc aatcatccta aaaaaaaaaa aaaaaaaaaa
4561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
4621 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//