LOCUS AF103796 2719 bp mRNA linear HUM 26-JAN-1999
DEFINITION Homo sapiens placenta-specific ATP-binding cassette transporter
(ABCP) mRNA, complete cds.
ACCESSION AF103796
VERSION AF103796.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2719)
AUTHORS Allikmets,R., Gerrard,B., Hutchinson,A. and Dean,M.
TITLE Characterization of the human ABC superfamily: isolation and
mapping of 21 new genes using the expressed sequence tags database
JOURNAL Hum. Mol. Genet. 5 (10), 1649-1655 (1996)
PUBMED 8894702
REFERENCE 2 (bases 1 to 2719)
AUTHORS Allikmets,R., Schriml,L.M., Hutchinson,A., Romano-Spica,V. and
Dean,M.
TITLE A human placenta-specific ATP-binding cassette gene (ABCP) on
chromosome 4q22 that is involved in multidrug resistance
JOURNAL Cancer Res. 58 (23), 5337-5339 (1998)
PUBMED 9850061
REFERENCE 3 (bases 1 to 2719)
AUTHORS Allikmets,R., Schriml,L.M., Hutchinson,A., Romano-Spica,V. and
Dean,M.
TITLE Direct Submission
JOURNAL Submitted (30-OCT-1998) LGD, NCI, Bldg. 560 Rm. 21-18, NCI-FCRDC,
Frederick, MD 21703, USA
FEATURES Location/Qualifiers
source 1..2719
/db_xref="H-InvDB:HIT000069389"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q22"
/tissue_type="placenta"
gene 1..2719
/gene="ABCP"
/note="multidrug resistance gene"
CDS 205..2172
/gene="ABCP"
/note="ABC transporter"
/codon_start=1
/product="placenta-specific ATP-binding cassette
transporter"
/protein_id="AAD09188.1"
/translation="MSSSNVEVFIPVSQGNTNGFPATVSNDLKAFTEGAVLSFHNICY
RVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGL
SGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNER
INRVIEELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILSLDEPTTGLDS
STANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGY
FESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAE
IYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNP
QASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVV
EKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFV
MMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLS
WLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
GLWKNHVALACMIVIFLTIAYLKLLFLKKYS"
BASE COUNT 799 a 545 c 564 g 811 t
ORIGIN
1 tttaggaacg caccgtgcac atgcttggtg gtcttgttaa gtggaaactg ctgctttaga
61 gtttgtttgg aaggtccggg tgactcatcc caacatttac atccttaatt gttaaagcgc
121 tgcctccgag cgcacgcatc ctgagatcct gagcctttgg ttaagaccga gctctattaa
181 gctgaaaaga taaaaactct ccagatgtct tccagtaatg tcgaagtttt tatcccagtg
241 tcacaaggaa acaccaatgg cttccccgcg acagtttcca atgacctgaa ggcatttact
301 gaaggagctg tgttaagttt tcataacatc tgctatcgag taaaactgaa gagtggcttt
361 ctaccttgtc gaaaaccagt tgagaaagaa atattatcga atatcaatgg gatcatgaaa
421 cctggtctca acgccatcct gggacccaca ggtggaggca aatcttcgtt attagatgtc
481 ttagctgcaa ggaaagatcc aagtggatta tctggagatg ttctgataaa tggagcaccg
541 cgacctgcca atttcaaatg taattcaggt tacgtggtac aagatgatgt tgtgatgggc
601 actctgacgg tgagagaaaa cttacagttc tcagcagctc ttcggcttgc aacaactatg
661 acgaatcatg aaaaaaacga acggattaac agggtcattg aagagttagg tctggataaa
721 gtggcagact ccaaggttgg aactcagttt atccgtggtg tgtctggagg agaaagaaaa
781 aggactagta taggaatgga gcttatcact gatccttcca tcttgtcctt ggatgagcct
841 acaactggct tagactcaag cacagcaaat gctgtccttt tgctcctgaa aaggatgtct
901 aagcagggac gaacaatcat cttctccatt catcagcctc gatattccat cttcaagttg
961 tttgatagcc tcaccttatt ggcctcagga agacttatgt tccacgggcc tgctcaggag
1021 gccttgggat actttgaatc agctggttat cactgtgagg cctataataa ccctgcagac
1081 ttcttcttgg acatcattaa tggagattcc actgctgtgg cattaaacag agaagaagac
1141 tttaaagcca cagagatcat agagccttcc aagcaggata agccactcat agaaaaatta
1201 gcggagattt atgtcaactc ctccttctac aaagagacaa aagctgaatt acatcaactt
1261 tccgggggtg agaagaagaa gaagatcaca gtcttcaagg agatcagcta caccacctcc
1321 ttctgtcatc aactcagatg ggtttccaag cgttcattca aaaacttgct gggtaatccc
1381 caggcctcta tagctcagat cattgtcaca gtcgtactgg gactggttat aggtgccatt
1441 tactttgggc taaaaaatga ttctactgga atccagaaca gagctggggt tctcttcttc
1501 ctgacgacca accagtgttt cagcagtgtt tcagccgtgg aactctttgt ggtagagaag
1561 aagctcttca tacatgaata catcagcgga tactacagag tgtcatctta tttccttgga
1621 aaactgttat ctgatttatt acccatgagg atgttaccaa gtattatatt tacctgtata
1681 gtgtacttca tgttaggatt gaagccaaag gcagatgcct tcttcgttat gatgtttacc
1741 cttatgatgg tggcttattc agccagttcc atggcactgg ccatagcagc aggtcagagt
1801 gtggtttctg tagcaacact tctcatgacc atctgttttg tgtttatgat gattttttca
1861 ggtctgttgg tcaatctcac aaccattgca tcttggctgt catggcttca gtacttcagc
1921 attccacgat atggatttac ggctttgcag cataatgaat ttttgggaca aaacttctgc
1981 ccaggactca atgcaacagg aaacaatcct tgtaactatg caacatgtac tggcgaagaa
2041 tatttggtaa agcagggcat cgatctctca ccctggggct tgtggaagaa tcacgtggcc
2101 ttggcttgta tgattgttat tttcctcaca attgcctacc tgaaattgtt atttcttaaa
2161 aaatattctt aaatttcccc ttaattcagt atgatttatc ctcacataaa aaagaagcac
2221 tttgattgaa gtattcaatc aagttttttt gttgttttct gttcccttgc catcacactg
2281 ttgcacagca gcaattgttt taaagagata catttttaga aatcacaaca aactgaatta
2341 aacatgaaag aacccaagac atcatgtatc gcatattagt taatctcctc agacagtaac
2401 catggggaag aaatctggtc taatttatta atctaaaaaa ggagaattga attctggaaa
2461 ctcctgacaa gttattactg tctctggcat ttgtttcctc atctttaaaa tgaataggta
2521 ggttagtagc ccttcagtct taatacttta tgatgctatg gtttgccatt atttaatata
2581 tgacaaatgt attaatgcta tactggaaat gtaaaattga aaatatgttg gaaaaaagat
2641 tctgtcttat agggtaaaaa aagccaccgg tgatagaaaa aaaatctttt tgataagcac
2701 attaaagtta atagaactt
//