LOCUS       AF103402                 322 bp    mRNA    linear   HUM 26-JUL-2016
DEFINITION  Homo sapiens isolate donor D clone D42K immunoglobulin kappa light
            chain variable region mRNA, partial cds.
ACCESSION   AF103402
VERSION     AF103402.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 322)
  AUTHORS   de Wildt,R.M., Hoet,R.M., van Venrooij,W.J., Tomlinson,I.M. and
            Winter,G.
  TITLE     Analysis of heavy and light chain pairings indicates that receptor
            editing shapes the human antibody repertoire
  JOURNAL   J. Mol. Biol. 285 (3), 895-901 (1999)
   PUBMED   9887257
REFERENCE   2  (bases 1 to 322)
  AUTHORS   de Wildt,R.M.T., Hoet,R.M.A., van Venrooij,W.J., Tomlinson,I.M. and
            Winter,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-1998) Centre for Protein Engineering, MRC, Hills
            Road, Cambridge CB2 2QH, UK
FEATURES             Location/Qualifiers
     source          1..322
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="donor D"
                     /db_xref="taxon:9606"
                     /clone="D42K"
                     /cell_type="B cell"
                     /tissue_type="peripheral blood"
                     /note="isolated from patient with systemic lupus
                     erythematosus"
     CDS             <1..>322
                     /codon_start=1
                     /product="immunoglobulin kappa light chain variable
                     region"
                     /protein_id="AAD16573.1"
                     /translation="AVSLGERATINCKSSQSVLHSSNNKNYLAWYQQKPGQPPKLLIK
                     WAFTRDSGVPDRFSGSGSGTDFTLTITSLQAEDVAVYYCQQYYGLPLTFGGGTKVEIK
                     RTVPA"
     V_region        <1..>322
BASE COUNT           77 a           88 c           84 g           73 t
ORIGIN      
        1 gctgtgtctc tgggcgagag ggccaccatc aactgcaagt ccagtcagag tgttttacac
       61 agctccaaca ataagaacta cttagcttgg taccagcaga aaccaggcca gcctcctaag
      121 ctgctcatta agtgggcatt tacccgggac tccggggtcc ctgaccgatt cagtggcagc
      181 gggtctggga cagatttcac tctcaccatc accagcctgc aggcggaaga tgtggcagtt
      241 tattactgtc agcaatatta tggtcttcct ctcactttcg gcggagggac caaggtggag
      301 atcaaacgaa ctgtgcctgc ac
//