LOCUS AF101074 1761 bp mRNA linear HUM 28-APR-1999
DEFINITION Homo sapiens step II splicing factor SLU7 mRNA, complete cds.
ACCESSION AF101074
VERSION AF101074.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1761)
AUTHORS Chua,K. and Reed,R.
TITLE Human step II splicing factor hSlu7 functions in restructuring the
spliceosome between the catalytic steps of splicing
JOURNAL Genes Dev. 13 (7), 841-850 (1999)
PUBMED 10197984
REFERENCE 2 (bases 1 to 1761)
AUTHORS Chua,K. and Reed,R.
TITLE Direct Submission
JOURNAL Submitted (23-OCT-1998) Cell Biology, Harvard Medical School, 240
Longwood, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..1761
/db_xref="H-InvDB:HIT000068638"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
CDS 1..1761
/function="involved in restructuring the spliceosome
between the catalytic steps of the pre-mRNA splicing
reaction"
/note="similar to Saccharomyces cerevisiae splicing factor
Slu7"
/codon_start=1
/product="step II splicing factor SLU7"
/protein_id="AAD13774.1"
/translation="MSATVVDAVNAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRK
LGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWY
KRGVKENSIITKYRKGACENCGAMTHKKKDCFERPRRVGAKFTGTNIAPDEHVQPQLM
FDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKH
QWGEEEPNSQTEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLR
NLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEA
YDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLA
QTEDYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFF
KYSYCTGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKH
RKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEM
EAYRMKRQRPDDPMASFLGQ"
BASE COUNT 649 a 308 c 435 g 369 t
ORIGIN
1 atgtcagcca cagttgtaga tgcagttaat gctgcacccc tatcggggtc caaagaaatg
61 agtttggaag aaccaaagaa gatgaccaga gaggactgga gaaagaagaa ggagctagaa
121 gaacagcgaa aattgggcaa tgctcctgca gaagttgatg aagaaggaaa agacatcaac
181 ccccatattc ctcagtatat ttcttcagtg ccatggtata ttgatccttc aaaaagacct
241 actttaaaac accagagacc acaaccagaa aaacaaaagc agttcagctc atctggagaa
301 tggtacaaga ggggtgtaaa agagaattcc ataattacta agtaccgcaa aggagcatgt
361 gaaaattgtg gggccatgac acacaaaaag aaagactgct ttgagagacc taggcgagtt
421 ggagccaaat ttacaggtac taatatagct ccagatgaac atgtccagcc tcaactgatg
481 tttgactatg atgggaagag ggatcggtgg aatggctaca atccagaaga acacatgaaa
541 attgttgaag agtatgccaa agttgatttg gcaaaacgaa cattgaaagc ccagaaactc
601 caagaggaat tagcctcagg aaaattagtg gaacaggcta attctccaaa acaccagtgg
661 ggagaagagg aaccaaattc tcagacggaa aaagatcata atagtgaaga tgaggatgaa
721 gataaatatg cagatgatat tgacatgcct ggacagaatt ttgactccaa gagacgaatt
781 actgtccgga atctcaggat tcgagaagat attgcaaaat atttgaggaa tttagatcca
841 aattctgcct actatgatcc aaaaactaga gcaatgagag agaatcctta tgccaatgca
901 ggaaagaatc cagatgaagt gagttatgct ggagataact ttgttaggta cacaggagat
961 accatttcaa tggctcagac acagttgttt gcatgggaag cctatgacaa gggatctgaa
1021 gtgcatctac aggcagatcc tacaaagcta gagctgttgt ataagtcctt caaagtcaaa
1081 aaagaagatt tcaaagaaca gcagaaagaa agcatcctgg aaaagtatgg tggccaagaa
1141 catttggatg cccctccagc tgaattgctt ttagcccaga ctgaagacta tgtggagtac
1201 tcaagacatg ggacagtcat caaaggacag gagcgggctg ttgcctgctc taagtatgag
1261 gaggatgtga agatccacaa tcacacacat atctggggat cgtactggaa agaaggccga
1321 tggggataca aatgctgtca ctcttttttc aagtattcct attgtactgg agaagctggg
1381 aaggagattg ttaactctga ggagtgtatt ataaatgaga taactgggga agaatctgtg
1441 aaaaaacctc aaaccctcat ggagctgcat caagaaaaac tgaaagagga aaagaagaag
1501 aagaaaaaga aaaagaagaa gcatcgaaag agcagttcag atagtgatga tgaagaaaag
1561 aagcatgaaa aattgaaaaa ggcactgaac gcagaggagg cccgccttct tcatgtcaag
1621 gagaccatgc agattgatga gaggaagcgg ccttacaata gcatgtatga aactcgagaa
1681 cctactgaag aggaaatgga ggcatataga atgaaacgtc agaggccaga tgaccccatg
1741 gcctctttcc ttggacagta g
//