LOCUS AF098638 2490 bp mRNA linear HUM 14-MAR-2000
DEFINITION Homo sapiens rabaptin-4 mRNA, complete cds.
ACCESSION AF098638
VERSION AF098638.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2490)
AUTHORS Nagelkerken,B., Van Anken,E., Van Raak,M., Gerez,L., Mohrmann,K.,
Van Uden,N., Holthuizen,J., Pelkmans,L. and Van Der Sluijs,P.
TITLE Rabaptin4, a novel effector of the small GTPase rab4a, is recruited
to perinuclear recycling vesicles
JOURNAL Biochem. J. 346 (Pt 3), 593-601 (2000)
PUBMED 10698684
REFERENCE 2 (bases 1 to 2490)
AUTHORS Nagelkerken,B., van Anken,E., van Raak,M. and van der Sluijs,P.
TITLE Direct Submission
JOURNAL Submitted (13-OCT-1998) Cell Biology, Utrecht University School of
Medicine, Heidelberglaan 100, Utrecht 3584CX, Netherlands
FEATURES Location/Qualifiers
source 1..2490
/db_xref="H-InvDB:HIT000068552"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
CDS 1..2490
/function="effector of endosomal GTPases Rab4a and Rab5a;
stabilizes Rab4a on recycling endosomes"
/codon_start=1
/product="rabaptin-4"
/protein_id="AAC70781.1"
/translation="MAQPGPASQPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRA
KFKELYLAKEEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTKQEA
IDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERTQWAQYREYAEREIADLRRR
LSEGQEEENLENEMKKAQEDAEKLRSVVMPMEKEIAALKDKLTEAEDKIKELEASKVK
ELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQL
KHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEDDEQQRLNKRKD
HKKADVEEEIKIPVVCALTQEESSAQLSNEEEHLDSTRGSVHSLDAGLLLPSGDPFSK
SDNDMFKDGLRRAQSTDSLGTSGSLQSKALGYNYKAKSAGNLDESDFGPLVGADSVSE
NFDTASLGSLQMPSGFMLTKDQERAIKAMTPEQEETASLLSSVTQGMESAYVSPSGYR
LVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQ
ANDQLEKTMKDKQELEDFIKQSSEDSSHQISALVLRAQASEILLEELQQGLSQAKRDV
QEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQQAEDFILPDTTEALRELVL
KYREDIINVRTAADHVEEKLKAEILFLKEQIQAEQCLKENLEETLQLEIENCKEEIAS
ISSLKAELERIKVEKGQATVEQLMFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQ
LERIRQADSLERIRAILNDTKLTDINQLPET"
BASE COUNT 871 a 457 c 633 g 529 t
ORIGIN
1 atggcgcagc cgggcccggc ttcccagcct gacgtttctc ttcagcaacg ggtagcagaa
61 ttggaaaaaa ttaatgcaga atttttacgt gcacaacagc agcttgaaca agaatttaat
121 caaaagagag caaaatttaa ggagttatat ttggctaaag aggaggatct gaagaggcaa
181 aatgcagtat tacaagctgc acaagatgat ttgggacacc ttcgaaccca gctgtgggaa
241 gctcaagcag agatggagaa tattaaggcg attgccacag tctctgagaa caccaagcaa
301 gaagctatag atgaagtgaa aagacagtgg agagaagaag ttgcttcact tcaggctgtt
361 atgaaagaaa cagttcgtga ctatgagcac cagttccacc ttaggctgga gcaggagcga
421 acacagtggg cacagtatag agaatacgca gagagggaaa tagctgattt aagaagaagg
481 ctgtctgaag gtcaagagga ggaaaattta gaaaatgaaa tgaaaaaggc ccaagaggat
541 gctgagaaac ttcggtccgt tgtgatgcca atggaaaagg aaattgcagc tttgaaggat
601 aaactgacag aggctgaaga caaaattaaa gagctggagg cctcaaaggt taaagaactg
661 aatcattatc tggaagctga gaaatcttgt aggactgatc tagagatgta tgtagctgtt
721 ttgaatactc agaaatctgt tctacaggaa gatgctgaga aactgcggaa agaattgcat
781 gaagtttgcc atctcttgga gcaagagcga caacaacaca accagttaaa acatacgtgg
841 cagaaggcca atgaccagtt tctggaatct cagcgtttac tgatgagaga catgcagcga
901 atggagattg tgctaacttc agaacagctc cgacaagttg aagaactgaa gaagaaagat
961 caggaggatg atgaacaaca aagactcaat aagagaaagg atcacaaaaa agcagatgtt
1021 gaggaagaaa taaaaatacc agtagtgtgt gctttaactc aagaagaatc ttcagcccag
1081 ttatcaaatg aagaggagca tttagacagc acccgtggct cagttcattc cttagatgca
1141 ggcttgctgt tgccatctgg agatcctttc agtaaatcgg acaatgacat gtttaaagat
1201 ggactcagga gagcacagtc tacagacagc ttgggaacct cgggctcatt gcaatccaaa
1261 gctttaggct ataactacaa agcaaaatct gctggaaacc tggacgagtc agattttgga
1321 ccactggtag gagcagattc agtgtctgag aactttgata ctgcatccct tgggtcactc
1381 cagatgccaa gtgggtttat gttaaccaaa gatcaggaaa gagcaatcaa ggcgatgaca
1441 ccagaacaag aagagacagc gtccctcctc tccagcgtta cccagggcat ggagagtgcc
1501 tatgtgtctc ctagtggtta tcgtttagtt agtgaaacag aatggaatct cttgcagaaa
1561 gaggtacata atgctggaaa taaacttggt agacgttgtg atatgtgttc caattacgaa
1621 aaacagttac aaggaattca gattcaggag gctgaaacga gagaccaggt gaaaaaacta
1681 cagctgatgc taaggcaagc taatgaccag ttagagaaga caatgaaaga taagcaggag
1741 ctggaagact tcataaagca aagcagcgaa gattcgagtc accagatctc tgcactcgtc
1801 ctaagagccc aggcctccga gatcttactt gaagagttac agcaggggct ttcccaggca
1861 aagagggatg ttcaggaaca gatggcggtg ctgatgcagt cacgggaaca ggtttcagaa
1921 gagctggtga ggttacagaa agataatgac agtctccagg gaaagcacag cctgcatgtg
1981 tcattacagc aagcagaaga cttcatcctc ccagacacta cagaggcact gcgggagttg
2041 gtattaaaat accgtgagga catcattaat gtgcggacag cagcagacca cgtagaagaa
2101 aagctgaagg ctgagatact tttcctaaaa gagcagatcc aagcagaaca gtgtttaaaa
2161 gaaaatcttg aagaaactct gcaactagaa atagaaaact gcaaggagga aatagcttct
2221 atttctagcc taaaagctga attagaaaga ataaaagtgg aaaaaggaca ggctaccgtt
2281 gaacaactaa tgtttgaaga gaagaataaa gctcagagat tacagacaga attagatgtc
2341 agtgagcaag tccagaggga ttttgtaaag ctttcacaga cccttcaggt gcagttagag
2401 cggatccggc aagctgactc cttggagaga atccgggcaa ttctgaatga tactaaactg
2461 acagacatta accagcttcc tgagacatga
//