LOCUS AF097366 2221 bp mRNA linear HUM 11-FEB-2000
DEFINITION Homo sapiens cone sodium-calcium potassium exchanger (NCKX2) mRNA,
complete cds.
ACCESSION AF097366
VERSION AF097366.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2221)
AUTHORS Prinsen,C.F., Szerencsei,R.T. and Schnetkamp,P.P.
TITLE Molecular cloning and functional expression of the
potassium-dependent sodium-calcium exchanger from human and chicken
retinal cone photoreceptors
JOURNAL J. Neurosci. 20 (4), 1424-1434 (2000)
PUBMED 10662833
REFERENCE 2 (bases 1 to 2221)
AUTHORS Prinsen,C.F.M., Szerencsei,R.T. and Schnetkamp,P.P.M.
TITLE Direct Submission
JOURNAL Submitted (05-OCT-1998) Physiology and Biophysics, University of
Calgary, 3330 Hospital Drive, NW, Calgary, AB T2N 4N1, Canada
FEATURES Location/Qualifiers
source 1..2221
/db_xref="H-InvDB:HIT000068478"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9p13-p22"
/tissue_type="retina"
gene 1..2221
/gene="NCKX2"
CDS 63..2048
/gene="NCKX2"
/note="NCKX family member; involved in Na-Ca+K exchange in
brain and retina"
/codon_start=1
/product="cone sodium-calcium potassium exchanger"
/protein_id="AAF21810.1"
/translation="MDLQQSTTITSLEKWCLDESLSGCRRHYSVKKKLKLIRVLGLFM
GLVAISTVSFSISAFSETDTQSTGEASVVSGPRVAQGYHQRTLLDLNDKILDYTPQPP
LSKEGESENSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPS
LTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILF
VIGMCALFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCY
VVFMKFNVQVEKWVKQMINRNKVVKVTAPEAQAKPSAARDKDEPTLPAKPRLQRGGSS
ASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKK
KCHVDENERQNGAANHVEKIELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQT
ADEEEDQPLSLAWPSETRKQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSIT
WIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVS
SSVGSNIFDITVGLPLPWLLYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSIALC
KWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI"
BASE COUNT 574 a 545 c 515 g 587 t
ORIGIN
1 tgaaagaacc atctggttga gtctaaagtt ggaagatcac catatccacc agaagaccca
61 ggatggatct gcaacaaagc accaccatca cttccctaga gaaatggtgt ttggatgagt
121 cactgtctgg ctgcagaaga cattatagtg tcaagaaaaa actgaagtta attcgagtct
181 taggcctttt catgggtctg gtagccatta gcactgtctc attttcaatc agtgcctttt
241 ctgagacaga tacacagagc acaggagagg ccagtgttgt aagtggccct agggtagcac
301 agggttacca tcagagaact ctcttagatt taaatgacaa gattctggat tatactccac
361 agccacctct ttctaaggaa ggcgagtctg agaatagtac agatcacgcc caaggagact
421 acccgaaaga catcttttcc cttgaggaga gaagaaaagg tgcgatcatt ctgcatgtca
481 ttggaatgat ctacatgttc atagccttag ccattgtctg tgatgagttc tttgttcctt
541 ctttgactgt catcactgaa aaactgggca tctctgatga tgtggctgga gccaccttca
601 tggctgcagg agggtcagcc ccagaacttt tcacatctct cataggggta tttatcgctc
661 acagcaacgt tggcataggc acaattgtag gttcagcagt attcaacatc ctctttgtta
721 ttggcatgtg tgctctgttt tctagagaaa tcttaaacct gacatggtgg ccgctctttc
781 gagatgtgtc tttctacatt gttgacttga tcatgctgat catatttttc ctggataatg
841 tcatcatgtg gtgggaaagc ttgcttctct taacagctta tttttgctat gtggttttca
901 tgaaattcaa cgtccaagta gaaaaatggg tgaagcaaat gataaaccgc aataaggtcg
961 tcaaggtgac agcaccagaa gcccaagcaa agccatctgc agccagggac aaggatgaac
1021 cgactctacc ggctaagccg cgtctccagc gaggtggaag ctctgcctcc ctccacaaca
1081 gtctcatgag gaatagcatc ttccaactca tgatacacac ccttgaccca ctcgccgaag
1141 aacttggatc atatggaaaa ctaaaatatt atgacacaat gactgaagaa gggaggttca
1201 gagaaaaggc ttcaattctc cacaagatcg ccaagaagaa atgtcatgtg gatgagaacg
1261 agcggcagaa tggggctgcc aaccacgtgg aaaaaattga gcttccaaac agcaccagca
1321 cagatgttga aatgacacca tccagtgatg cttcagaacc tgtacaaaat ggaaatctct
1381 cccacaacat tgaaggtgca gaagcccaga ccgctgatga ggaggaggac cagcctctca
1441 gccttgcctg gccttctgaa acccgcaagc aagtcacgtt tctgattgtt ttccccatag
1501 tgtttcctct ctggattacg ttacctgacg ttcgcaaacc ttcatcgagg aagttttttc
1561 ccatcacgtt ctttggctcc attacctgga ttgcagtatt ctcttacttg atggtctggt
1621 gggcgcacca ggttggagag acaattggca tcagtgaaga gattatgggc ctgaccatct
1681 tggctgctgg gacctccatc cctgatctta tcaccagtgt catagtggcc cggaaggggt
1741 taggggacat ggctgtgtcc agctctgttg gaagcaacat ttttgacatc actgtagggc
1801 tcccactgcc ctggctcctg tacaccgtca ttcacagatt ccagccagtg gctgtcagca
1861 gcaatggcct tttctgtgcc atcgtccttc tcttcatcat gctgctcttc gtcatcctct
1921 ctatcgccct ctgcaagtgg cgaatgaaca aaatcctggg cttcatcatg tttggcctct
1981 actttgtgtt cctggtggtg agcgttctcc tagaagacag aattcttaca tgccccgtct
2041 ccatctagca ggaaaagcca tatcttgcac cagcagcatg aatggtccct ccacactctg
2101 ggctctgggc tccttgacct cttgagaaga ggcagctggc acacagccct gggtgccaag
2161 tgtccctcct tggtgaattt gaggagagat ggattcacac tgggcccatt cacttcacag
2221 g
//