LOCUS AF096300 3864 bp mRNA linear HUM 03-MAR-1999
DEFINITION Homo sapiens HPK/GCK-like kinase HGK mRNA, complete cds.
ACCESSION AF096300
VERSION AF096300.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3864)
AUTHORS Yao,Z., Zhou,G., Wang,X.S., Brown,A., Diener,K., Gan,H. and
Tan,T.H.
TITLE A novel human STE20-related protein kinase, HGK, that specifically
activates the c-Jun N-terminal kinase signaling pathway
JOURNAL J. Biol. Chem. 274 (4), 2118-2125 (1999)
PUBMED 9890973
REFERENCE 2 (bases 1 to 3864)
AUTHORS Yao,Z., Zhou,G., Wang,X.S., Brown,A., Diener,K., Gan,H. and Tan,T.
TITLE Direct Submission
JOURNAL Submitted (01-OCT-1998) Amgen Inc., 3200 Walnut Street, Boulder, CO
80301, USA
FEATURES Location/Qualifiers
source 1..3864
/db_xref="H-InvDB:HIT000068461"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 80..3577
/function="activates the c-Jun N-terminal kinase signaling
pathway"
/note="STE20-related protein kinase"
/codon_start=1
/product="HPK/GCK-like kinase HGK"
/protein_id="AAD16137.1"
/translation="MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRH
VKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLW
LVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVL
LTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWS
CGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ
RPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVP
EQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLL
AERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEE
RRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRRPHPQHSQQP
PPPQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRSPVLSRRDSPLQGSGQQNSQA
GQRNSTSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSS
SKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTALAKELRAVEDVRPPHKVTDY
SSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVE
SEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVG
FSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVN
LLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSW
LRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKP
YHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTH
VRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMP
TSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRS
GGSSQVYFMTLGRTSLLSW"
BASE COUNT 1129 a 837 c 1047 g 851 t
ORIGIN
1 aattcgagga tccgggtacc atggcacaga gcgacagaga catttattgt tatttgtttt
61 ttggtggcaa aaagggaaaa tggcgaacga ctcccctgca aaaagtctgg tggacatcga
121 cctctcctcc ctgcgggatc ctgctgggat ttttgagctg gtggaagtgg ttggaaatgg
181 cacctatgga caagtctata agggtcgaca tgttaaaacg ggtcagttgg cagccatcaa
241 agttatggat gtcactgagg atgaagagga agaaatcaaa ctggagataa atatgctaaa
301 gaaatactct catcacagaa acattgcaac atattatggt gctttcatca aaaagagccc
361 tccaggacat gatgaccaac tctggcttgt tatggagttc tgtggggctg ggtccattac
421 agaccttgtg aagaacacca aagggaacac actcaaagaa gactggatcg cttacatctc
481 cagagaaatc ctgaggggac tggcacatct tcacattcat catgtgattc accgggatat
541 caagggccag aatgtgttgc tgactgagaa tgcagaggtg aaacttgttg actttggtgt
601 gagtgctcag ctggacagga ctgtggggcg gagaaatacg ttcataggca ctccctactg
661 gatggctcct gaggtcatcg cctgtgatga gaacccagat gccacctatg attacagaag
721 tgatctttgg tcttgtggca ttacagccat tgagatggca gaaggtgctc cccctctctg
781 tgacatgcat ccaatgagag cactgtttct cattcccaga aaccctcctc cccggctgaa
841 gtcaaaaaaa tggtcgaaga agttttttag ttttatagaa gggtgcctgg tgaagaatta
901 catgcagcgg ccctctacag agcagctttt gaaacatcct tttataaggg atcagccaaa
961 tgaaaggcaa gttagaatcc agcttaagga tcatatagat cgtaccagga agaagagagg
1021 cgagaaagat gaaactgagt atgagtacag tgggagtgag gaagaagagg aggaagtgcc
1081 tgaacaggaa ggagagccaa gttccattgt gaacgtgcct ggtgagtcta ctcttcgccg
1141 agatttcctg agactgcagc aggagaacaa ggaacgttcc gaggctcttc ggagacaaca
1201 gttactacag gagcaacagc tccgggagca ggaagaatat aaaaggcaac tgctggcaga
1261 gagacagaag cggattgagc agcagaaaga acagaggcga cggctagaag agcaacaaag
1321 gagagagcgg gaggctagaa ggcagcagga acgtgaacag cgaaggagag aacaagaaga
1381 aaagaggcgt ctagaggagt tggagagaag gcgcaaagaa gaagaggaga ggagacgggc
1441 agaagaagaa aagaggagag ttgaaagaga acaggagtat atcaggcgac agctagaaga
1501 ggagcagcgg cacttggaag tccttcagca gcagctgctc caggagcagg ccatgttact
1561 gcatgaccat aggaggccgc acccgcagca ctcgcagcag ccgccaccac cgcagcagga
1621 aaggagcaag ccaagcttcc atgctcccga gcccaaagcc cactacgagc ctgctgaccg
1681 agcgcgagag gttcctgtga gaacaacatc tcgctcccct gttctgtccc gtcgagattc
1741 cccactgcag ggcagtgggc agcagaatag ccaggcagga cagagaaact ccaccagtat
1801 tgagcccagg cttctgtggg agagagtgga gaagctggtg cccagacctg gcagtggcag
1861 ctcctcaggg tccagcaact caggatccca gcccgggtct caccctgggt ctcagagtgg
1921 ctccggggaa cgcttcagag tgagatcatc atccaagtct gaaggctctc catctcagcg
1981 cctggaaaat gcagtgaaaa aacctgaaga taaaaaggaa gttttcagac ccctcaagcc
2041 tgctggcgaa gtggatctga ccgcactggc caaagagctt cgagcagtgg aagatgtacg
2101 gccacctcac aaagtaacgg actactcctc atccagtgag gagtcgggga cgacggatga
2161 ggaggacgac gatgtggagc aggaaggggc tgacgagtcc acctcaggac cagaggacac
2221 cagagcagcg tcatctctga atttgagcaa tggtgaaacg gaatctgtga aaaccatgat
2281 tgtccatgat gatgtagaaa gtgagccggc catgacccca tccaaggagg gcactctaat
2341 cgtccgccag actcagtccg ctagtagcac actccagaaa cacaaatctt cctcctcctt
2401 tacacctttt atagacccca gattactaca gatttctcca tctagcggaa caacagtgac
2461 atctgtggtg ggattttcct gtgatgggat gagaccagaa gccataaggc aagatcctac
2521 ccggaaaggc tcagtggtca atgtgaatcc taccaacact aggccacaga gtgacacccc
2581 ggagattcgt aaatacaaga agaggtttaa ctctgagatt ctgtgtgctg ccttatgggg
2641 agtgaatttg ctagtgggta cagagagtgg cctgatgctg ctggacagaa gtggccaagg
2701 gaaggtctat cctcttatca accgaagacg atttcaacaa atggacgtac ttgagggctt
2761 gaatgtcttg gtgacaatat ctggcaaaaa ggataagtta cgtgtctact atttgtcctg
2821 gttaagaaat aaaatacttc acaatgatcc agaagttgag aagaagcagg gatggacaac
2881 cgtaggggat ttggaaggat gtgtacatta taaagttgta aaatatgaaa gaatcaaatt
2941 tctggtgatt gctttgaaga gttctgtgga agtctatgcg tgggcaccaa agccatatca
3001 caaatttatg gcctttaagt catttggaga attggtacat aagccattac tggtggatct
3061 cactgttgag gaaggccaga ggttgaaagt gatctatgga tcctgtgctg gattccatgc
3121 tgttgatgtg gattcaggat cagtctatga catttatcta ccaacacatg taagaaagaa
3181 cccacactct atgatccagt gtagcatcaa accccatgca atcatcatcc tccccaatac
3241 agatggaatg gagcttctgg tgtgctatga agatgagggg gtttatgtaa acacatatgg
3301 aaggatcacc aaggatgtag ttctacagtg gggagagatg cctacatcag tagcatatat
3361 tcgatccaat cagacaatgg gctggggaga gaaggccata gagatccgat ctgtggaaac
3421 tggtcacttg gatggtgtgt tcatgcacaa aagggctcaa agactaaaat tcttgtgtga
3481 acgcaatgac aaggtgttct ttgcctctgt tcggtctggt ggcagcagtc aggtttattt
3541 catgacctta ggcaggactt ctcttctgag ctggtagaag cagtgtgatc cagggattac
3601 tggcctccag agtcttcaag atcctgagaa cttggaattc cttgtaactg gagctcggag
3661 ctgcaccgag ggcaaccagg acagctgtgt gtgcagacct catgtgttgg gttctctccc
3721 ctccttcctg ttcctcttat ataccagttt atccccattc tttttttttt tcttactcca
3781 aaataaatca aggctgcaat gcagctggtg ctgttcagat tccaaaaaaa aaaaaaaacc
3841 atggtacccg gatcctcgaa ttcc
//