LOCUS AF095286 1630 bp mRNA linear HUM 20-APR-1999
DEFINITION Homo sapiens guanine deaminase GDA mRNA, complete cds.
ACCESSION AF095286
VERSION AF095286.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1630)
AUTHORS Yuan,G., Bin,J.C., McKay,D.J. and Snyder,F.F.
TITLE Cloning and characterization of human guanine deaminase.
Purification and partial amino acid sequence of the mouse protein
JOURNAL J. Biol. Chem. 274 (12), 8175-8180 (1999)
PUBMED 10075721
REFERENCE 2 (bases 1 to 1630)
AUTHORS Snyder,F.F. and Yuan,G.
TITLE Direct Submission
JOURNAL Submitted (26-SEP-1998) Medical Genetics, University of Calgary,
3330 Hospital Drive N.W., Calgary, Alberta T2N 4N1, Canada
FEATURES Location/Qualifiers
source 1..1630
/db_xref="H-InvDB:HIT000068426"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
CDS 94..1458
/note="guanase; guanine aminohydrolase"
/codon_start=1
/product="guanine deaminase GDA"
/protein_id="AAD25978.1"
/translation="MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVF
LEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEW
LTKYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKF
GQRAFVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSC
SETLMGELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTV
MAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGG
YSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVG
KEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPF
SSSV"
BASE COUNT 448 a 383 c 385 g 414 t
ORIGIN
1 cggcagccgc ccgcagctgc agagagtccc gctgcgtctc cgccgcgtgc gccctcctcg
61 accagcagac ccgcgctgcg ctccgccgct gacatgtgtg ccgctcagat gccgcccctg
121 gcgcacatct tccgagggac gttcgtccac tccacctgga cctgccccat ggaggtgctg
181 cgggatcacc tcctcggcgt gagcgacagc ggcaaaatag tgtttttaga agaagcatct
241 caacaggaaa aactggccaa agaatggtgc ttcaagccgt gtgaaataag agaactgagc
301 caccatgagt tcttcatgcc tgggctggtt gatacacaca tccatgcctc tcagtattcc
361 tttgctggaa gtagcataga cctgccactc ttggagtggc tgaccaagta cacatttcct
421 gcagaacaca gattccagaa catcgacttt gcagaagaag tatataccag agttgtcagg
481 agaacactaa agaatggaac aaccacagct tgttactttg caacaattca cactgactca
541 tctctgctcc ttgccgacat tacagataaa tttggacagc gggcatttgt gggcaaagtt
601 tgcatggatt tgaatgacac ttttccagaa tacaaggaga ccactgagga atcgatcaag
661 gaaactgaga gatttgtgtc agaaatgctc caaaagaact attctagagt gaagcccata
721 gtgacaccac gtttttccct ctcctgctct gagactttga tgggtgaact gggcaacatt
781 gctaaaaccc gtgatttgca cattcagagc catataagtg aaaatcgtga tgaagttgaa
841 gctgtgaaaa acttataccc cagttataaa aactacacat ctgtgtatga taaaaacaat
901 cttttgacaa ataagacagt gatggcacac ggctgctacc tctctgcaga agaactgaac
961 gtattccatg aacgaggagc atccatcgca cactgtccca attctaattt atcgctcagc
1021 agtggatttc taaatgtgct agaagtcctg aaacatgaag tcaagatagg gctgggtaca
1081 gacgtggctg gtggctattc atattccatg cttgatgcaa tcagaagagc agtgatggtt
1141 tccaatatcc ttttaattaa taaggtaaat gagaaaagcc tcaccctcaa agaagtcttc
1201 agactagcta ctcttggagg aagccaagcc ctggggctgg atggtgagat tggaaacttt
1261 gaagtgggca aggaatttga tgccatcctg atcaacccca aagcatccga ctctcccatt
1321 gacctgtttt atggggactt ttttggtgat atttctgagg ctgttatcca gaagttcctc
1381 tatctaggag atgatcgaaa tattgaagag gtttatgtgg gcggaaagca ggtggttccg
1441 ttttccagct cagtgtaaga ccctcgggcg tctacaaagt tctcctggga ttagcgtggt
1501 tctgcatctc ccttgtgccc aggtggagtt agaaagtcaa aaaatagtac cttgttcttg
1561 ggatgactat ccctttctgt gtctagttac agtattcact tgacaaatag ttcgaaggaa
1621 gttgcactaa
//