LOCUS AF093772 1144 bp mRNA linear HUM 25-SEP-2000
DEFINITION Homo sapiens mitoxantrone resistance protein 2 mRNA, complete
sequence.
ACCESSION AF093772
VERSION AF093772.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1144)
AUTHORS Miyake,K., Mickley,L., Litman,T., Zhan,Z., Robey,R., Cristensen,B.,
Brangi,M., Greenberger,L., Dean,M., Fojo,T. and Bates,S.E.
TITLE Molecular cloning of cDNAs which are highly overexpressed in
mitoxantrone-resistant cells: demonstration of homology to ABC
transport genes
JOURNAL Cancer Res. 59 (1), 8-13 (1999)
PUBMED 9892175
REFERENCE 2 (bases 1 to 1144)
AUTHORS Mickley,L.A., Miyake,K., Fojo,A.T. and Bates,S.E.
TITLE Direct Submission
JOURNAL Submitted (23-SEP-1998) Medicine Branch, NIH/NCI, 9000 Rockville
Pike, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..1144
/db_xref="H-InvDB:HIT000068403"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
misc_feature 255..877
/note="mitoxantrone resistance protein 2; MXR2; highly
overexpressed in cells resistant to mitoxantrone; sequence
contains possible frame shift"
BASE COUNT 317 a 240 c 234 g 353 t
ORIGIN
1 ttcttggaca tcattaatgg agattccact gctgtggcat taaacagaga agaagacttt
61 aaagccacag agatcataga gccttccaag caggataagc cactcataga aaaattagcg
121 gagatttatg tcaactcctc cttctacaaa gagacaaaag ctgaattaca tcaactttcc
181 gggggtgaga agaagaagaa gatcacagtc ttcaaggaga tcagctacac cacctccttc
241 tgtcatcaac tcagatgggt ttccaagcgt tcattcaaaa cttgctgggt aatccccagg
301 cctctatagc tcagatcatt gtcacagtcg tactgggact ggttataggt gccatttact
361 ttgggctaaa aaatgattct actggaatcc agaacagagc tggggttctc ttcttcctga
421 cgaccaacca gtgtttcagc agtgtttcag ccgtggaact ctttgtggta gagaagaagc
481 tcttcataca tgaatacatc agcggatact acagagtgtc atcttatttc cttggaaaac
541 tgttatctga tttattaccc atggggatgt ttaccagtat tatatttacc tgtatagtgt
601 acttcatgtt aggattgaag ccaaggcaga tgccttcttc gttatgatgt ttacccttat
661 gatggtggct tattcagcca gttccatggc actggccata gcagcaggtc agagtgtggt
721 ttctgtagca acacttctca tgaccatctg ttttgtgttt atgatgattt tttcaggtct
781 gttggtcaat ctcacaacca ttgcatcttg gctgtcatgg cttcagtact tcagcattcc
841 acgatatgga tttacggctt tgcagcataa tgaatttttt gggacaaaac ttctgcccag
901 gactcaatgc aacaggaaac aatccttgta actatgcaac atgtactggc gaagaatatt
961 tggtaaagca gggcatcgat ctctcaccct ggggcttgtg gaagaatcac gtggccttgg
1021 cttgtatgat tgttattttc ctcacaattg cctacctgaa attgttattt cttaaaaaat
1081 attcttaaat ttccccttaa ttcagtatga tttatcctca cataaaaaag aagcactttg
1141 attg
//