LOCUS AF093771 1469 bp mRNA linear HUM 25-SEP-2000
DEFINITION Homo sapiens mitoxantrone resistance protein 1 mRNA, partial
sequence.
ACCESSION AF093771
VERSION AF093771.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1469)
AUTHORS Miyake,K., Mickley,L., Litman,T., Zhan,Z., Robey,R., Cristensen,B.,
Brangi,M., Greenberger,L., Dean,M., Fojo,T. and Bates,S.E.
TITLE Molecular cloning of cDNAs which are highly overexpressed in
mitoxantrone-resistant cells: demonstration of homology to ABC
transport genes
JOURNAL Cancer Res. 59 (1), 8-13 (1999)
PUBMED 9892175
REFERENCE 2 (bases 1 to 1469)
AUTHORS Mickley,L.A., Miyake,K., Fojo,A.T. and Bates,S.E.
TITLE Direct Submission
JOURNAL Submitted (23-SEP-1998) Medicine Branch, NIH/NCI, 9000 Rockville
Pike, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..1469
/db_xref="H-InvDB:HIT000068402"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
misc_feature <1..838
/note="mitoxantrone resistance protein 1; MXR1; highly
overexpressed in cells resistant to mitoxantrone; sequence
includes possible frame shift"
BASE COUNT 430 a 294 c 282 g 463 t
ORIGIN
1 cattaaacag agaagaagac tttaaagcca cagagatcat agagccttcc aagcaggata
61 agccactcat agaaaaatta gcggagattt atgtcaactc ctccttctac aaagagacaa
121 aagctgaatt acatcaactt tccgggggtg agaagaagaa gaagatcaca gtcttcaagg
181 agatcagcta caccacctcc ttctgtcatc aactcagatg ggtttccaag cgttcattca
241 aaaacttgct gggtaatccc caggcctcta tagctcagat cattgtcaca gtcgtactgg
301 gactggttat aggtgccatt tactttgggc taaaaaatga ttctactgga atccagaaca
361 gagctggggt tctcttcttc ctgacgacca accagtgttt cagcagtgtt tcagccgtgg
421 aactctttgt ggtagagaag aagctcttca tacatgaata catcagcgga tactacagag
481 tgtcatctta tttccttgga aaactgttat ctgatttatt acccatgggg atgttaccag
541 tattatattt acctgtatag tgtacttcat gttaggattg aagccaaagg cagatgcctt
601 cttcgttatg atgtttaccc ttatgatggt ggcttattca gccagttcca tggcactggc
661 catagcagca ggtcagagtg tggtttctgt agcaacactt ctcatgacca tctgttttgt
721 gtttatgatg attttttcag gtctgttggt caatctcaca accattgcat cttggctgtc
781 atggcttcag tacttcagca ttccacgata tggatttacg gctttgcagc ataatgaatt
841 ttttgggaca aaacttctgc ccaggactca atgcaacagg aaacaatcct tgtaactatg
901 caacatgtac tggcgaagaa tatttggtaa agcagggcat cgatctctca ccctggggct
961 tgtggaagaa tcacgtggcc ttggcttgta tgattgttat tttcctcaca attgcctacc
1021 tgaaattgtt atttcttaaa aaatattctt aaatttcccc ttaattcagt atgatttatc
1081 ctcacataaa aaagaagcac tttgattgaa gtattcaatc aagttttttt gtgttttctg
1141 ttcccttgcc atcacactgt tgcacagcag caattgtttt aaagagatac atttttagaa
1201 atcacaacaa actgaattaa acatgaaaga acccaagaca tcatgtatcg catattagtt
1261 aatctcctca gacagtaacc atggggaaga aatctggtct aatttattaa tctaaaaaag
1321 gagaattgaa ttctggaaac tcctgacaag ttattactgt ctctggcatt tgtttcctca
1381 tctttaaaat gaataggtag gttagtagcc cttcagtctt aatactttat gatgctatgg
1441 tttgccatta tttaataaat gacaaatgt
//