LOCUS AF093264 1800 bp mRNA linear HUM 05-NOV-1998
DEFINITION Homo sapiens homer-2b mRNA, complete cds.
ACCESSION AF093264
VERSION AF093264.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1800)
AUTHORS Xiao,B., Tu,J.C., Petralia,R.S., Yuan,J.P., Doan,A., Breder,C.D.,
Ruggiero,A., Lanahan,A.A., Wenthold,R.J. and Worley,P.F.
TITLE Homer regulates the association of group 1 metabotropic glutamate
receptors with multivalent complexes of homer-related, synaptic
proteins
JOURNAL Neuron 21 (4), 707-716 (1998)
PUBMED 9808458
REFERENCE 2 (bases 1 to 1800)
AUTHORS Tu,J.C., Xiao,B., Yuan,J.P., Lanahan,A.A., Leoffert,K., Li,M.,
Linden,D.J. and Worley,P.F.
TITLE Homer binds a novel proline-rich motif and links group 1
metabotropic glutamate receptors with IP3 receptors
JOURNAL Neuron 21 (4), 717-726 (1998)
PUBMED 9808459
REFERENCE 3 (bases 1 to 1800)
AUTHORS Xiao,B., Tu,J.C., Lanahan,A.A. and Worley,P.F.
TITLE Direct Submission
JOURNAL Submitted (21-SEP-1998) Neuroscience, Johns Hopkins University
School of Medicine, 725 N. Wolfe, Baltomore, MD 21205, USA
FEATURES Location/Qualifiers
source 1..1800
/db_xref="H-InvDB:HIT000068389"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/tissue_type="frontal cortex"
CDS 1..1065
/note="EVH1/WH1-domain protein; carboxy-terminal
coiled-coil domain; selectively binds group 1 metabotropic
receptors and links IP3 receptors"
/codon_start=1
/product="homer-2b"
/protein_id="AAC71028.1"
/translation="MGEQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNS
YRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEK
FQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDEEKASHAGPANT
QLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQWKRQFSIC
RDENDRLRNKIDELEEQCSEINREKEKNTQLKRRIEELEAELREKETELKDLRKQSEI
IPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLD
GKIDDLHDFRRGLSKLGTDN"
BASE COUNT 517 a 433 c 472 g 378 t
ORIGIN
1 atgggggagc agccgatctt caccacccga gcgcatgtct tccagattga ccccaacacc
61 aagaagaact ggatgcctgc gagcaagcag gcggtcaccg tttcctactt ctatgatgtc
121 acaaggaaca gctatcggat catcagtgtg gacggagcca aggtgatcat aaacagcaca
181 atcacaccga atatgacctt caccaaaacg tcacagaagt ttgggcagtg ggccgacagc
241 agagccaaca cagtgtttgg tttggggttt tcctctgagc agcagctgac aaagtttgca
301 gagaaattcc aggaggtgaa agaagctgcc aagatagcca aagacaagac gcaggagaaa
361 atcgagacct caagtaatca ttcccaagaa tctgggcgtg aaaccccatc ttctactcag
421 gcatccagtg tcaacgggac ggacgaggaa aaggcctctc acgccggtcc agccaacaca
481 caactgaagt ctgagaatga caagctgaag attgccttga cgcagagcgc agccaacgtg
541 aagaagtggg agatcgagct gcagaccctt cgggagagca atgcacggct gaccacagca
601 ctgcaggagt cggcagccag tgtggagcag tggaagaggc agttctccat ctgccgtgat
661 gagaatgacc ggctccgcaa caagattgat gagctggaag aacaatgcag tgagatcaac
721 agagagaagg agaagaacac gcagctgaag aggaggatcg aggagctgga ggcagagctc
781 cgagaaaagg agacagagct gaaagatctc cgaaaacaaa gtgaaatcat acctcagctc
841 atgtcagagt gcgaatatgt ctctgagaag ctagaggcgg cagagagaga caatcaaaac
901 ctggaagaca aagtgcgttc cttaaagaca gacattgagg agagcaaata ccgacagcgc
961 cacctgaagg tggagttgaa gagcttcctg gaggtgctgg acgggaagat tgacgacctg
1021 catgacttcc gccgagggct ctccaagctg ggcaccgata actagggctg gccgaggccc
1081 aggccccgcc cgtgagtccc aagcgtgtgt gcgagaccag atagctctag gacgttcttc
1141 tgtgtgcatt gcttctgtaa atgcaggcgc agtttgtcgt gtttccaaac cagttgtgcc
1201 gtccactcac tccttttcag aatagaaatc tcctctcgct tctctggcct tgtgaggttg
1261 tggacaactg gaagattctg actcaggaat ccagaactag gtctaccttc aacatttatg
1321 cagtcagggc agggatgttt atatctttca taagggctgt tgcaaccata tgaactgaaa
1381 aaacacgcat tttgtaatcc aaatattgat attctttaca ccaagccatc aggctccttt
1441 tatcaaatag cattcagagt atttgaatgt ccaccagaca ccagccccgg ggggcacaga
1501 gagaacaaca ttcctctctg tcaacatcga gaggctttaa aacaactgtt tagtggaaac
1561 tttctgagag atggaaaaca agcttctggt gggtgcattt tctggcccgg agttgcctgc
1621 atccacgcta ctgccccctg ccccccgccc ccccagtttg tacggttgca acagtgttcc
1681 ttttcttggt tttaatttct gagcagatga tttgctgtgg gaacagcaca cagtgagggt
1741 gcctagcaca atgtctggca caaagtaggt gcttaataaa tatttgttca attaaaaaaa
//