LOCUS AF092047 4477 bp DNA linear HUM 02-FEB-1999
DEFINITION Homo sapiens homeobox protein Six3 (SIX3) gene, complete cds.
ACCESSION AF092047
VERSION AF092047.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4477)
AUTHORS Granadino,B., Gallardo,M.E., Lopez-Rios,J., Sanz,R., Ramos,C.,
Ayuso,C., Bovolenta,P. and Rodriguez de Cordoba,S.
TITLE Genomic cloning, structure, expression pattern, and chromosomal
location of the human SIX3 gene
JOURNAL Genomics 55 (1), 100-105 (1999)
PUBMED 9889003
REFERENCE 2 (bases 1 to 4477)
AUTHORS Granadino,B., Gallardo,M.E., Lopez-Rios,J., Sanz,R., Ramos,C.,
Ayuso,C., Bovolenta,P. and Rodriguez de Cordoba,S.
TITLE Direct Submission
JOURNAL Submitted (15-SEP-1998) Department of Immunology, Centro de
Investigaciones Biologicas-CSIC, Velazquez, 144, Madrid 28006,
Spain
FEATURES Location/Qualifiers
source 1..4477
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16-p21; between D2S119 and D2S288"
gene 893..4477
/gene="SIX3"
mRNA join(893..2080,3740..4477)
/gene="SIX3"
/product="homeobox protein Six3"
CDS join(1275..2080,3740..3932)
/gene="SIX3"
/codon_start=1
/product="homeobox protein Six3"
/protein_id="AAD11939.1"
/translation="MVFRSPLDLYSSHFLLPNFADSHHRSILLASSGGGNGAGGGGGA
GGGSGGGNGAGGGGAGGAGGGGGGGSRAPPEELSMFQLPTLNFSPEQVASVCETLEET
GDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKE
SHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTR
SLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIG
PSGMRSLAEPGCPTHGSAESPSTAASPTTSVSSLTERADTGTSILSVTSSDSECDV"
BASE COUNT 898 a 1380 c 1314 g 885 t
ORIGIN
1 gaattctggg aagaaacaaa gagttgagtt gcttcttaag atggaaagaa gtgtactgtt
61 tggactgtta ttttaaaata cagggtggtg ggggaaatcg aggctccttg gccggggagg
121 gagtaaagag aagcctaatt gatgaagagg gagttgaggt gaatgcggtc catgggcacc
181 gatgggggag gcaagagcgg cctccagcac cctgggaatt gggctcaggc tccctggcgc
241 cagataccct cggaatccgg gatccccggc tggcgccacg gcccgctggg ccaaggtcgg
301 tgcttggtgg gccccatgat ctcatctctc ctttcttcct tgccactatt agtgctcaca
361 taggcagaaa gaggcggccc gacgtgcaaa ccatgtgcaa accgcgcccg ctgggctggt
421 cagccgtctt tccttgcctg ccgacctgga ctatgtggag cctgggggac cctcttgcct
481 cccaacaaaa tcccctctct attgcacatc ccattcaaca actctgccca gggcttttcg
541 aatttctgga tcaacttctt taggaaaaag ggaagaagaa gtctcagaga cagcggtaga
601 gaaaagagga gagagaggga gaagacagaa gagaggaggg ggaggtagcg agattaagag
661 ttgcaaagat aaaaaaaatt ctctttatcc ccccacttct ccctccttcc ctgctctccc
721 cctccccccg ccctctggct aagtggtaaa accgtcctta cgttctcggt attgattggc
781 agggctgaca gtgattggca gtggttgccg tggcaacgcc acaacgacac gccacagacc
841 aatagaaaag cgaaacaaaa tgtttcaatg ctgcactcac tgtggattta ggggagatat
901 tatgaggctg ttgtcattag ggcgattgcg gtggaatcgc tgaatcttga ctcggcggtg
961 gttggctctc cctctcctct ctccctctcc ctctccctct ctgtctcggg ttctctctct
1021 gcgcgcgcgc accgggccgc tctcctacct ccctctctat gtggctgcgc gggtgtgtgt
1081 gtgtgtggat gtgtgtgggg tgtgggtgtc ccttacgccc ttcctcctct ccctcctcct
1141 cctgctcccc cctcctttcc ttctcctcct cccccctctc ctctccctcc tcctggtcct
1201 catcgcccct ctctcctctt cctcccctct ctcttcctct ccctgaattt tctcctctcc
1261 tctcaggtca gtccatggta ttccgctccc ccctagacct ctattcctcc cacttcttgt
1321 tgccaaactt cgccgattct caccaccgct ccatacttct ggcgagtagc ggcggcggga
1381 acggtgcggg aggcggcggc ggcgcgggag gcggcagcgg cggcgggaac ggtgcgggag
1441 gcggcggtgc tggcggagca ggcggcggcg gcggcggcgg ctccagggcc cccccggaag
1501 agttgtccat gttccagctg cccaccctca acttctcgcc ggagcaggtg gccagcgtct
1561 gtgagacgct ggaggagacg ggcgacatcg agcggctggg ccgcttcctc tggtcgctgc
1621 ccgtggcccc cggggcgtgc gaggccatca acaaacacga gtcgatcctg cgcgcgcgcg
1681 ccgtggtcgc cttccacacg ggcaacttcc gcgacctcta ccacatcctt gagaaccaca
1741 agttcaccaa ggagtctcac ggcaagctgc aggccatgtg gctcgaggcg cactaccagg
1801 aggccgagaa gctgcgcggc cgcccactcg gcccggtgga caagtaccgc gtgcgcaaga
1861 agttcccgct gccacgcacc atctgggacg gcgagcagaa gacgcattgc ttcaaggagc
1921 ggactcggag cctgttgcgg gagtggtacc tacaggaccc ctaccccaac cccagcaaga
1981 aacgcgaact ggcgcaggcc accggcctca ctcccacaca agtaggcaac tggtttaaga
2041 accggcggca gcgcgaccgc gccgcggcgg ccaagaacag gttagtggcg gggcccgcgg
2101 cctggctaca gcctcagagg cctgggaagg ggagaggggt tgagatgggg ctagcggagc
2161 ggccgctgag agccagggaa gccgtgactc ctggccagtc ggagaaagtt tccgcttgtc
2221 cgggacgcgc ggaagagggg gccgggctgg ctgtgggtgt attgattgct ttgaccaaga
2281 ggggctttcg tcagggcaga gagtgtgtgc ttgcgacccg agtacccgca gcccctggga
2341 gacttagccc tgcgctgcac ccgtgcctgc ctcctcagcc ctgccgccag ctcggcgatc
2401 ctctggagcc tagagacagg gagggaagga aagcactctt tgccatctgg ttcttatttc
2461 tgtgcgttgc aaaaccccga gagaaatcca ctagcgtcag agagaggaaa gtgaacctgg
2521 gtccctatca caaggggaaa aggccagagg ccactgcgca gcgggcctgt ttccccgcaa
2581 cgctgcacgt tgcctgaccg ggagcaggag agccgggctg ggagtggaga ggcctagcgt
2641 gtgcgtgtgt gtgtgtgtgt gcacgccccg tgtgcatgta ctcgccctcc tgtttcagcc
2701 gaggagaatc cctttggtcc tctaagctgg gaagcgggca cgagcagcct cgttgccggc
2761 aagttggcca caaagtcaca aaattgtata gggcttgacc aacatcacag gagctgggcc
2821 tgggggaagg agaaaaagaa ccagagggaa agaagtggat aggcgaaagg agtggggaga
2881 gaagggagaa agaaaagagg aagttgggtg aaagccctga tgtggagcct gtgtctttct
2941 ctatccagcc aggaaggccc agggcctggt gtacttcagg gagcaggacc cccagctgct
3001 gacagctgcc cgtgggtggg ggctgggtgt gagtttctgg aggtgtgttc gagtttaggc
3061 ggccgggacc tgagcccatg gccctctcac ccctgccgtg gagcccactt ttcgtctgat
3121 gaggggagcg cccagggtca agccaaggcc tccttgtgga gagaattcca gacaccaggt
3181 ccaggcagaa ggttcccggt gggggaaagg gcagctggag actgctctgt gcgcctctct
3241 tgccttctcc tttgcccctt ttctgtctcc ctgctctttc cccacttttc caccgccagc
3301 tttcctattt tctctaccct cggtcctgcg ctctgcgctg gcatccagag agcaaagtat
3361 gcagttctac ccggagactg gccgggcggt ggggaacccg cagctcccgg tgtgtgtttg
3421 agggagcagg gacggggtta ctaggggaac tcgaccggtc gcggggcagc cggctcagtt
3481 tgaagagccc cagggactgc ggagggaaga agcgcccggc tcctctccga cttctgcttc
3541 tccagggctt ggcgtacttt gtcgcttgca cccaaggcct ccccaagcgg ccgggctcgg
3601 gttctgcctc tcctccgagg ccagcctcta tctgagaaga cttgggatgc tcccgaaagc
3661 ggaatgggga gcggcggcgc gggggagccg ggtggcgggc ctctgtgtca gggcgggcgc
3721 ggatctcttt ctcccgcagg ctccagcacc aggccattgg accgagcggc atgcgctcgc
3781 tggccgagcc cggctgcccc acgcacggct cggcagagtc gccgtccacg gcggccagcc
3841 cgaccaccag cgtgtccagc ctgacggagc gcgcggacac cggcacctcc atcctctcgg
3901 taacctccag cgactcggaa tgtgatgtat gatagccaag gccgccctcc tccctctcct
3961 tcccctcctc ccccactcct tcccctccgc ctcctagccc tcctcctctt cctcctcttc
4021 cttctcctcc tccatcccca gaacaaaccg aaatcaggat acccaaccat acacacatac
4081 aagtccacac acactcccac cccagccaaa aatatataaa aaacaagaaa ataacaaatt
4141 aaccgcaaac tatcaacaac ccccaaccac catctaccac tacggccacc ccaaaggacc
4201 ccgacgccaa cagacagtca aacgctgatg ttgcgggcag aaaacataaa agaggtgaca
4261 attgtatact ttctaggaca agcacggctt ctcctttcgg ttcccatgga cccggcaccc
4321 cacctgcatg acgatttatt tgtatctggg aaaatattct ctctagttaa aaatgattta
4381 aagagtcgac tatacaaaga tcaatcacca ccacgaggac aagagggcaa tgagcatgaa
4441 cagacagagt aagaaacaag tcgccgtctc cgttccg
//