LOCUS AF091501 3612 bp mRNA linear HUM 30-NOV-1998
DEFINITION Homo sapiens receptor protein patched 2 (PTCH2) mRNA, complete cds.
ACCESSION AF091501
VERSION AF091501.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3612)
AUTHORS Carpenter,D., Stone,D.M., Brush,J., Ryan,A., Armanini,M.,
Frantz,G., Rosenthal,A. and de Sauvage,F.J.
TITLE Characterization of two patched receptors for the vertebrate
hedgehog protein family
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (23), 13630-13634 (1998)
PUBMED 9811851
REFERENCE 2 (bases 1 to 3612)
AUTHORS de Sauvage,F.J. and Carpenter,D.
TITLE Direct Submission
JOURNAL Submitted (11-SEP-1998) Molecular Oncology, Genentech Inc, 1 DNA
Way, So. San Francisco, CA 94080, USA
FEATURES Location/Qualifiers
source 1..3612
/db_xref="H-InvDB:HIT000068329"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p32-p36"
gene 1..3612
/gene="PTCH2"
CDS 1..3612
/gene="PTCH2"
/note="12 TM receptor protein; Hedgehog receptor"
/codon_start=1
/product="receptor protein patched 2"
/protein_id="AAC79847.1"
/translation="MTRSPPLRELPPSYTPPARTAAPQILAGSLKAPLWLRAYFQGLL
FSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELHYTKE
KLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNKIC
YKSGVPLIENGMIEWMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDP
EQLLEELGPFASLEGFRELLDKAQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVA
HELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRG
DYQTHDIGWSEEQASTVLQAWQRRFVQLAQEALPENASQQIHAFSSTTLDDILHAFSE
VSAARVVGGYLLMLAYACVTMLRWDCAQSQGSVGLAGVLLVALAVASGLGLCALLGIT
FNAATTQVLPFLALGIGVDDVFLLAHAFTEALPGTPLQERMGECLQRTGTSVVLTSIN
NMAAFLMAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLC
CFSSPCSAQVIQILPQELGDGTVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLV
PPPSDPLGSELFSPGGSTRDLLGQEEETRQKAACKSLPCARWNLAHFARYQFAPLLLQ
SHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVA
LVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRNWLQGIQAAFDQ
DWASGRITRHSYRNGSEDGALAYKLLIQTGDAQEPLDFSQLTTRKLVDREGLIPPELF
YMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGENLRIPPAQPLEFAQFPFLL
RGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILL
VCTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGV
EFTVHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSHFDFIVRYF
FAALTVLTLLGLLHGLVLLPVLLSILGPPPEVIQMYKESPEILSPPAPQGGGLRWGAS
SSLPQSFARVTTSMTVAIHPPPLPGAYIHPAPDEPPWSPAATSSGNLSSRGPGPATG"
BASE COUNT 623 a 1201 c 1026 g 762 t
ORIGIN
1 atgactcgat cgccgcccct cagagagctg cccccgagtt acacaccccc agctcgaacc
61 gcagcacccc agatcctagc tgggagcctg aaggctccac tctggcttcg tgcttacttc
121 cagggcctgc tcttctctct gggatgcggg atccagagac attgtggcaa agtgctcttt
181 ctgggactgt tggcctttgg ggccctggca ttaggtctcc gcatggccat tattgagaca
241 aacttggaac agctctgggt agaagtgggc agccgggtga gccaggagct gcattacacc
301 aaggagaagc tgggggagga ggctgcatac acctctcaga tgctgataca gaccgcacgc
361 caggagggag agaacatcct cacacccgaa gcacttggcc tccacctcca ggcagccctc
421 actgccagta aagtccaagt atcactctat gggaagtcct gggatttgaa caaaatctgc
481 tacaagtcag gagttcccct tattgaaaat ggaatgattg agtggatgat tgagaagctg
541 tttccgtgcg tgatcctcac ccccctcgac tgcttctggg agggagccaa actccaaggg
601 ggctccgcct acctgcccgg ccgcccggat atccagtgga ccaacctgga tccagagcag
661 ctgctggagg agctgggtcc ctttgcctcc cttgagggct tccgggagct gctagacaag
721 gcacaggtgg gccaggccta cgtggggcgg ccctgtctgc accctgatga cctccactgc
781 ccacctagtg cccccaacca tcacagcagg caggctccca atgtggctca cgagctgagt
841 gggggctgcc atggcttctc ccacaaattc atgcactggc aggaggaatt gctgctggga
901 ggcatggcca gagaccccca aggagagctg ctgagggcag aggccctgca gagcaccttc
961 ttgctgatga gtccccgcca gctgtacgag catttccggg gtgactatca gacacatgac
1021 attggctgga gtgaggagca ggccagcaca gtgctacaag cctggcagcg gcgctttgtg
1081 cagctggccc aggaggccct gcctgagaac gcttcccagc agatccatgc cttctcctcc
1141 accaccctgg atgacatcct gcatgcgttc tctgaagtca gtgctgcccg tgtggtggga
1201 ggctatctgc tcatgctggc ctatgcctgt gtgaccatgc tgcggtggga ctgcgcccag
1261 tcccagggtt ccgtgggcct tgccggggta ctgctggtgg ccctggcggt ggcctcaggc
1321 cttgggctct gtgccctgct cggcatcacc ttcaatgctg ccactaccca ggtgctgcct
1381 ttcttggctc tgggaatcgg cgtggatgac gtattcctgc tggcgcatgc cttcacagag
1441 gctctgcctg gcacccctct ccaggagcgc atgggcgagt gtctgcagcg cacgggcacc
1501 agtgtcgtac tcacatccat caacaacatg gccgccttcc tcatggctgc cctcgttccc
1561 atccctgcgc tgcgagcctt ctccctacag gcggccatag tggttggctg cacctttgta
1621 gccgtgatgc ttgtcttccc agccatcctc agcctggacc tacggcggcg ccactgccag
1681 cgccttgatg tgctctgctg cttctccagt ccctgctctg ctcaggtgat tcagatcctg
1741 ccccaggagc tgggggacgg gacagtacca gtgggcattg cccacctcac tgccacagtt
1801 caagccttta cccactgtga agccagcagc cagcatgtgg tcaccatcct gcctccccaa
1861 gcccacctgg tgcccccacc ttctgaccca ctgggctctg agctcttcag ccctggaggg
1921 tccacacggg accttctagg ccaggaggag gagacaaggc agaaggcagc ctgcaagtcc
1981 ctgccctgtg cccgctggaa tcttgcccat ttcgcccgct atcagtttgc cccgttgctg
2041 ctccagtcac atgccaaggc catcgtgctg gtgctctttg gtgctcttct gggcctgagc
2101 ctctacggag ccaccttggt gcaagacggc ctggccctga cggatgtggt gcctcggggc
2161 accaaggagc atgccttcct gagcgcccag ctcaggtact tctccctgta cgaggtggcc
2221 ctggtgaccc agggtggctt tgactacgcc cattcccaac gcgccctctt tgatctgcac
2281 cagcgcttca gttccctcaa ggcggtgctg cccccaccgg ccacccaggc accccgcacc
2341 tggctgcact attaccgcaa ctggctacag ggaatccagg ctgcctttga ccaggactgg
2401 gcttctgggc gcatcacccg ccactcgtac cgcaatggct ctgaggatgg ggccctggcc
2461 tacaagctgc tcatccagac tggagacgcc caggagcctc tggatttcag ccagctgacc
2521 acaaggaagc tggtggacag agagggactg attccacccg agctcttcta catggggctg
2581 accgtgtggg tgagcagtga ccccctgggt ctggcagcct cacaggccaa cttctacccc
2641 ccacctcctg aatggctgca cgacaaatac gacaccacgg gggagaacct tcgcatcccg
2701 ccagctcagc ccttggagtt tgcccagttc cccttcctgc tgcgtggcct ccagaagact
2761 gcagactttg tggaggccat cgagggggcc cgggcagcat gcgcagaggc cggccaggct
2821 ggggtgcacg cctaccccag cggctccccc ttcctcttct gggaacagta tctgggcctg
2881 cggcgctgct tcctgctggc cgtctgcatc ctgctggtgt gcactttcct cgtctgtgct
2941 ctgctgctcc tcaacccctg gacggctggc ctcatagtgc tggtcctggc gatgatgaca
3001 gtggaactct ttggtatcat gggtttcctg ggcatcaagc tgagtgccat ccccgtggtg
3061 atccttgtgg cctctgtagg cattggcgtt gagttcacag tccacgtggc tctgggcttc
3121 ctgaccaccc agggcagccg gaacctgcgg gccgcccatg cccttgagca cacatttgcc
3181 cccgtgaccg atggggccat ctccacattg ctgggtctgc tcatgcttgc tggttcccac
3241 tttgacttca ttgtaaggta cttctttgcg gcgctgacag tgctcacgct cctgggcctc
3301 ctccatggac tcgtgctgct gcctgtgctg ctgtccatcc tgggcccgcc gccagaggtg
3361 atacagatgt acaaggaaag cccagagatc ctgagtccac cagctccaca gggaggcggg
3421 cttaggtggg gggcatcctc ctccctgccc cagagctttg ccagagtgac tacctccatg
3481 accgtggcca tccacccacc ccccctgcct ggtgcctaca tccatccagc ccctgatgag
3541 cccccttggt cccctgctgc cactagctct ggcaacctca gttccagggg accaggtcca
3601 gccactgggt ga
//