LOCUS       AF090386                1365 bp    mRNA    linear   HUM 14-JAN-1999
DEFINITION  Homo sapiens napsin A mRNA, complete cds.
ACCESSION   AF090386
VERSION     AF090386.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Tatnell,P.J., Powell,D.J., Hill,J., Smith,T.S., Tew,D.G. and Kay,J.
  TITLE     Napsins: new human aspartic proteinases. Distinction between two
            closely related genes
  JOURNAL   FEBS Lett. 441 (1), 43-48 (1998)
   PUBMED   9877162
REFERENCE   2  (bases 1 to 1365)
  AUTHORS   Tatnell,P.J., Hill,J., Kay,J., Powell,D.P. and Tew,D.G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-SEP-1998) Biosciences (MOMED), University of Wales
            Cardiff, PO Box 911 Museum Avenue, Cathays Park, Cardiff, Cardiff
            CF1 3US, Wales UK
FEATURES             Location/Qualifiers
     source          1..1365
                     /db_xref="H-InvDB:HIT000068204"
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="IMAGE Consortium 302091"
                     /tissue_type="lung; kidney"
     CDS             1..1263
                     /note="aspartic proteinase"
                     /codon_start=1
                     /product="napsin A"
                     /protein_id="AAD04917.1"
                     /translation="MSPPPLLQPLLLLLPLLNVEPSGATLIRIPLHRVQPGRRILNLL
                     RGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNL
                     WVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGI
                     KGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFS
                     FYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAK
                     GCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVW
                     FNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKS
                     SARVGLARARTRGADLGWGETAQAQFPG"
BASE COUNT          265 a          406 c          391 g          303 t
ORIGIN      
        1 atgtctccac caccgctgct gcaacccctg ctgctgctgc tgcctctgct gaatgtggag
       61 ccttccgggg ccacactgat ccgcatccct cttcatcgag tccaacctgg acgcaggatc
      121 ctgaacctac tgaggggatg gagagaacca gcagagctcc ccaagttggg ggccccatcc
      181 cctggggaca agcccatctt cgtacctctc tcgaactaca gggatgtgca gtattttggg
      241 gaaattgggc tgggaacgcc tccacaaaac ttcactgttg cctttgacac tggctcctcc
      301 aatctctggg tcccgtccag gagatgccac ttcttcagtg tgccctgctg gttacaccac
      361 cgatttgatc ccaaagcctc tagctccttc caggccaatg ggaccaagtt tgccattcaa
      421 tatggaactg ggcgggtaga tggaatcctg agcgaggaca agctgactat tggtggaatc
      481 aagggtgcat cagtgatttt cggggaggct ctctgggagc ccagcctggt cttcgctttt
      541 gcccattttg atgggatatt gggcctcggt tttcccattc tgtctgtgga aggagttcgg
      601 cccccgatgg atgtactggt ggagcagggg ctattggata agcctgtctt ctccttttac
      661 ctcaacaggg accctgaaga gcctgatgga ggagagctgg tcctgggggg ctcggacccg
      721 gcacactaca tcccacccct caccttcgtg ccagtcacgg tccctgccta ctggcagatc
      781 cacatggagc gtgtgaaggt gggcccaggg ctgactctct gtgccaaggg ctgtgctgcc
      841 atcctggata cgggcacgtc cctcatcaca ggacccactg aggagatccg ggccctgcat
      901 gcagccattg ggggaatccc cttgctggct ggggagtaca tcatcctgtg ctcggaaatc
      961 ccaaagctcc ccgcagtctc cttccttctt gggggggtct ggtttaacct cacggcccat
     1021 gattacgtca tccagactac tcgaaatggc gtccgcctct gcttgtccgg tttccaggcc
     1081 ctggatgtcc ctccgcctgc agggcccttc tggatcctcg gtgacgtctt cttggggacg
     1141 tatgtggccg tcttcgaccg cggggacatg aagagcagcg cccgggtggg cctggcgcgc
     1201 gctcgcactc gcggagcgga cctcggatgg ggagagactg cgcaggcgca gttccccggg
     1261 tgacgcccaa gtgaagcgca tgcgcagcgg gtggtcgcgg aggtcctgct acccagtaaa
     1321 aatccactat ttccattgag aaaaaacaaa aaaaaaaaaa aaaaa
//