LOCUS AF089854 3575 bp mRNA linear HUM 11-JUL-2001
DEFINITION Homo sapiens cell-line OV177 DRR1 (DRR1) mRNA, complete cds.
ACCESSION AF089854
VERSION AF089854.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3575)
AUTHORS Wang,L., Darling,J., Zhang,J.S., Liu,W., Qian,J., Bostwick,D.,
Hartmann,L., Jenkins,R., Bardenhauer,W., Schutte,J., Opalka,B. and
Smith,D.I.
TITLE Loss of expression of the DRR 1 gene at chromosomal segment 3p21.1
in renal cell carcinoma
JOURNAL Genes Chromosomes Cancer 27 (1), 1-10 (2000)
PUBMED 10564580
REFERENCE 2 (bases 1 to 3575)
AUTHORS Wang,L., Darling,J. and Smith,D.I.
TITLE Direct Submission
JOURNAL Submitted (02-SEP-1998) Lab Med Path, Mayo Clinic, 200 First Street
SW, Rochester, MN 55905, USA
FEATURES Location/Qualifiers
source 1..3575
/db_xref="H-InvDB:HIT000068172"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21.1"
/cell_line="OV177"
/tissue_type="ovary"
gene 1..3575
/gene="DRR1"
/note="down-regulated in renal cell carcinoma"
variation 548..645
/gene="DRR1"
/note="compared to GenBank Accession Number AF089853"
/replace=""
CDS 651..1085
/gene="DRR1"
/codon_start=1
/product="DRR1"
/protein_id="AAD16094.1"
/translation="MYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSH
QELHRELLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQELLR
RQQRLNQLEKPPEKEEDHAPEFIKVRENLRRIATLTSEEREL"
BASE COUNT 890 a 970 c 879 g 836 t
ORIGIN
1 aggcatcgaa ctgcggtagt acgggttacg gaatcactgt cgatgcccta gctggatcaa
61 tgtttcgatc tgatacgcca gcttggcacg aggctgcctc aggaagcttg gcttccctcc
121 catgggaagt gctggaatcc actcttgcct gaccctccca taagaaacaa gggaaattcc
181 tttacgtgag ccgccttgct cagaacaaag cttggcgtgt ttcttattcc tcatcaatct
241 gacaaaatgg gtatttattt gtgcctctca agcgtgtggc ttggacatga tgttccgcat
301 cgtggaagtg gccgtgcacc aagtggaata tctgttacta tagtaacagt tcctttttat
361 tgataccaga ataaacagga atgcaaaggc tgtctcactt gttggcacat ttcagcagcc
421 tccgttccca gaggtttaag aaccgccctc tagaggcagc cctccttgct agtctgggac
481 ttcccggtgg agtgaggaac ccagcaacac gctcctgact tcccttccca aggactcgac
541 ctgagaagga cacagcagtc tctgaatttc atgctctcct ctttgatgtg aagaaaatga
601 aaagctgaac agttgtggaa ctgtggatag agttagacaa taaggccgcc atgtactcgg
661 agatccagag ggagcgggca gacattgggg gcctgatggc ccggccagaa tacagagagt
721 ggaatccgga gctcatcaag cccaagaagc tgctgaaccc cgtgaaggcc tctcggagtc
781 accaggagct ccaccgggag ctgctcatga accacagaag gggccttggt gtggacagca
841 agccagagct gcagcgtgtc ctagagcacc gccggcggaa ccagctcatc aagaagaaga
901 aggaggagct ggaagccaag cggctgcagt gcccctttga gcaggagctg ctgagacggc
961 aacagaggct gaaccagctg gaaaaaccac cagagaagga agaggatcac gcccccgagt
1021 ttattaaagt cagggaaaac ctgcggagaa ttgccacact gaccagcgaa gagagagagc
1081 tgtagggcca gctgccgggc tcaggccact gcccaccctg gcctggacag cctccttcag
1141 cccttctgta cctggcagcc ctgggcccca ggccctggga cgtctgtgat gttcccacct
1201 gcttctgtag aaatgtgtca ccccagaggg cctggctctc cctgggaggc tggggcccct
1261 aagctcctag gttttccttc caagcaccca gccctcctgc tccaagaggg ataacctgca
1321 cccctccctg caaggggttc agagcccagc acaggagctt tctctggcag aattgaggag
1381 gaagaggtgg ccctctgact tgacaagcct tctgttctgc ccaggccttc ccaccaggaa
1441 tctccgaggc tccccagggc cccgcttctc cgtacacccc agctcctagg tctcagagaa
1501 ctcccccacc tgtggtttta cctgcagcca gcagagctta gcttcaagga cacctgcctt
1561 caaagccact gaggggagga agggcagggc agactgcagg tggccttgtt gctggcatcc
1621 cggccaggtg ggcggggatt aacaaagaca gctgtttagg gtcttctccc ttaacccatg
1681 ctttcataaa ccccttcgga cagcttcccc gtccaggctt tctaaccaca cctacccagg
1741 gtgccgcatt cctgcactca gaagtctgca gggtgcctca caaacttgat tgtgcataaa
1801 aatcactggg gatcttgtta atacagcttc taactcaata gatctgggag atcctgcatt
1861 tctaacaagc tcccaggtaa ggcggaggct gctggtgtga ggaccatgct gtgagcagca
1921 gggcgagagt gcccagggct gatatatatt ggaaatatca cccctgaagc catcgctggc
1981 ccccacctcc tgtggactga tgccccaggg attcccaccc cacttctgca accccaggta
2041 tccttcatta tccaccccat cccagactcc caccccaggg attgcccgtg aagactttgg
2101 cctagcaaat tgtgttggtt atgtgagtgt tgttttaatc agagatgtac atgattgcca
2161 atctgcattt cttaccagtg tgaccacact gttacgatgc aattctagcc aaaaaaaaaa
2221 aaaaaaaaaa aaaaaaattt ttttttttta ctttttccta gtcttatgga aagcaaatat
2281 acaatgattt tcagtaggct tctggaatag aaacagtggt ttgaagaccc cactgccacc
2341 tttatggact ggcccctttg agtctgaatc cccggcctct gtcacctgag acccaacccc
2401 tagctgggcc aactccagtg aattcaccca tttttcttct tcagaaggcc tttcctgtgt
2461 gagacccaca tattttaacc ttttgctcct atcccatttt taaagaatta gagaataaac
2521 caggcctgtt tcttttcccc tgaaatccct gcctctggct tcctaaaccc atcatctaag
2581 gtgacagagc agtgctggaa tagcatctcc tttcactttc ccaaaactgc cacagatagc
2641 tgccactggc atgctctttg attcctggaa gcaaacgtgg gactgtcgga ggaaagggat
2701 tgttctggtc ttactcataa ctgggtggtt tgagggtgac tgaagtcgtg cttttcctgt
2761 gtgtgctgcc agcacagggc tgtaaatgca gatattgcgc ctgtgtgcgt gtgtataagt
2821 caagctccaa gaggctcctg aatgtgactg gcgtgctgag aatgtgttta cgctgtttaa
2881 tgtctgccag gtgagggtta cactgaagat gcacaatccc taaaataaag atcaccactt
2941 ccccaaagaa gcagccctcg ggtccatgtg ttgttcagac atgtgaagag aagcaagaca
3001 gagggtctca gatggacgag ggctctccaa gggaatgcct ggggattcac ccagtggtcc
3061 ccagaggtgc tccatggagg caacaagtca ttccatgaag ccccagaggt agaagggacc
3121 tcaagcacca cgccctccag ggcagccgtg cagacgacct tggttcactt ttcaggggtc
3181 gtcccaactc tgtatctcca gccactccaa ctgtggaggc tgtaaatcca gattttcact
3241 gttccagtct cctttgcagc ttaggatggc tatgtgatca ggtgtggcca atgaaattga
3301 agaggaagtc tacctgggct tctgggaaag cttttccaat aaaagacaca ggcatggcta
3361 acacctccct gggcctcttc ttcctacctt gattgagggt gtgatgcctg gagccacagc
3421 agccactttg ctaccatgac aaaaaggcca agagaatcac agagtcattg accctatcat
3481 tatttcacca agccaatacc agccgccatc cttctccaga attcttgtaa ataaaataaa
3541 tccctctttg tttaaaaaaa aaaaaaaaaa aaaaa
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