LOCUS AF089726 7413 bp mRNA linear HUM 30-SEP-2000
DEFINITION Homo sapiens sodium bicarbonate cotransporter 2b (NBC2B) mRNA,
complete cds.
ACCESSION AF089726
VERSION AF089726.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7413)
AUTHORS Pushkin,A., Abuladze,N., Newman,D., Hwang,J. and Kurtz,I.
TITLE Homo sapiens sodium bicarbonate cotransporter 2b mRNA, complete cds
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7413)
AUTHORS Pushkin,A., Abuladze,N., Newman,D., Hwang,J. and Kurtz,I.
TITLE Direct Submission
JOURNAL Submitted (02-SEP-1998) Medicine, UCLA, 10833 Le Conte Ave, Los
Angeles, CA 90095, USA
FEATURES Location/Qualifiers
source 1..7413
/db_xref="H-InvDB:HIT000068159"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p22"
/tissue_type="kidney"
gene 1..7413
/gene="NBC2B"
CDS 72..3344
/gene="NBC2B"
/note="NBC-2b"
/codon_start=1
/product="sodium bicarbonate cotransporter 2b"
/protein_id="AAG16773.1"
/translation="MERFRLEKKLPGPDEEAVVDLGKTSSTVNTKFEKEELESHRAVY
IGVHVPFSKESRRRHRHRGHKHHHRRRKDKESDKEDGRESPSYDTPSQRVQFILGTED
DDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLH
SLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVREALLKRHHH
QNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGILASPQSAPGNLDNSKSGEIKGNGS
GGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGL
TEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDE
FLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPE
LQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGE
ATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYL
SLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGE
TYAFNMHNNLDKLTSYSCVCTEPPNPSNETLAQWKKDNITAHNISWRNLTVSECKKLR
GVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAV
FLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALL
CTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLS
ISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLY
GVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLL
WVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEK
EEAERMLQDDDDTVHLPFEGGSLLQIPVKALKYSPDKPVSVKISFEDEPRKKYVDAET
SL"
BASE COUNT 2274 a 1195 c 1372 g 2572 t
ORIGIN
1 ctcactgtcc ctggaatctt caagggagtt actgcattac atcatcagaa acaaggcatt
61 tctatattac tatggaaaga tttcgtctgg agaagaagtt acctggtcct gatgaagaag
121 ctgttgtgga tcttggcaaa actagctcaa ctgtgaacac caagtttgaa aaagaagaac
181 tagaaagtca tagagctgta tatattggtg ttcacgtccc gtttagtaaa gagagtcgtc
241 ggcgtcatag gcatcgcgga cacaaacatc accaccggag gagaaaagat aaagaatcag
301 ataaagaaga tggacgggaa tctccttctt atgatacacc atcccagaga gttcagttta
361 tccttggtac tgaagatgat gatgaagaac atattcccca tgatctcttc acggaaatgg
421 atgaactgtg ttacagagat ggagaagaat atgaatggaa agaaactgct agatggctga
481 aatttgaaga ggatgttgaa gatggcggtg accgatggag taaaccttat gtggcaactc
541 tctctttgca cagtcttttt gaactaagga gttgcatcct caatggaaca gtcatgctgg
601 atatgagagc aagcactcta gatgaaatag cagatatggt attagacaac atgatagctt
661 ctggccaatt agacgagtcc atacgagaga atgtcagaga agctcttctg aagagacatc
721 atcatcagaa tgagaaaaga ttcaccagtc ggattcctct tgttcgatct tttgcagata
781 taggcaagaa acattctgac cctcacttgc ttgaaaggaa tggtattttg gcctctcccc
841 agtctgctcc tggaaacttg gacaatagta aaagtggaga aattaaaggt aatggaagtg
901 gtggaagcag agaaaatagt actgttgact tcagcaaggt tgatatgaat ttcatgagaa
961 aaattcctac gggtgctgag gcatccaacg tcctggtggg cgaagtagac tttttggaaa
1021 ggccaataat tgcatttgtg agactggctc ctgctgtcct ccttacaggg ttgactgagg
1081 tccctgttcc aaccaggttt ttgtttttgt tattgggtcc agcgggcaag gcaccacagt
1141 accatgaaat tggacgatca atagccactc tcatgacaga tgagattttc catgatgtag
1201 cttataaagc aaaagacaga aatgacctct tatctggaat tgatgaattt ttagatcaag
1261 taactgtcct acctccagga gagtgggatc cttctatacg catagaacca ccaaaaagtg
1321 tcccttctca ggaaaagaga aagattcctg tgtttcacaa tggatctacc cccacactgg
1381 gtgagactcc taaagaggcc gctcatcatg ctgggcctga gctacagagg actggacggc
1441 tttttggtgg tttgatactt gacatcaaaa ggaaagcacc ttttttcttg agtgacttca
1501 aggatgcatt aagcctgcag tgcctggcct cgattctttt cctatactgt gcctgtatgt
1561 ctcctgtaat cacttttgga gggctgcttg gagaagctac agaaggcaga ataagtgcaa
1621 tagagtctct ttttggagca tcattaactg ggattgccta ttcattgttt gctgggcaac
1681 ctctaacaat attggggagc acaggtccag ttctagtgtt tgaaaaaatt ttatataaat
1741 tctgcagaga ttatcaactt tcttatctgt ctttaagaac cagtattggt ctgtggactt
1801 cttttttgtg cattgttttg gttgcaacag atgcaagcag ccttgtgtgt tatattactc
1861 gatttacaga agaggctttt gcagccctta tttgcatcat attcatctac gaggctttgg
1921 agaagctctt tgatttagga gaaacatatg catttaatat gcacaacaac ttagataaac
1981 tgaccagcta ctcatgtgta tgtactgaac ctccaaatcc cagcaatgaa actctagcac
2041 aatggaagaa agataatata acagcacaca atatttcctg gagaaatctt actgtttctg
2101 aatgtaaaaa acttcgtggt gtattcttgg ggtcagcttg tggtcatcat ggaccttata
2161 ttccagatgt gctcttttgg tgtgtcatct tgtttttcac aacatttttt ctgtcttcat
2221 tcctcaagca atttaagacc aagcgttact ttcctaccaa ggtgcgatcg acaatcagtg
2281 attttgctgt atttctcaca atagtaataa tggttacaat tgactacctt gtaggagttc
2341 catctcctaa acttcatgtt cctgaaaaat ttgagcctac tcatccagag agagggtgga
2401 tcataagccc actgggagat aatccttggt ggaccttatt aatagctgct attcctgctt
2461 tgctttgtac cattctcatc tttatggatc aacaaatcac agctgtaatt ataaacagaa
2521 aggaacacaa attgaagaaa ggagctggct atcaccttga tttgctcatg gttggcgtta
2581 tgttgggagt ttgctctgtc atgggacttc catggtttgt ggctgcaaca gtgttgtcaa
2641 taagtcatgt caacagctta aaagttgaat ctgaatgttc tgctccaggg gaacaaccca
2701 agtttttggg aattcgtgaa cagcgggtta cagggctaat gatttttatt ctaatgggcc
2761 tctctgtgtt catgacttca gtcctaaagt ttattccaat gcctgttctg tatggtgttt
2821 tcctttatat gggagtttcc tcattaaaag gaatccagtt atttgaccgt ataaaattat
2881 ttggaatgcc tgctaagcat cagcctgatt tgatatacct ccgttatgtg ccgctctgga
2941 aggtccatat tttcacagtc attcagctta cttgtttggt ccttttatgg gtgataaaag
3001 tttcagctgc tgcagtggtt tttcccatga tggttcttgc attagtgttt gtgcgcaaac
3061 tcatggacct gtgtttcacg aagagagaac ttagttggct tgatgatctt atgccagaaa
3121 gtaagaaaaa gaaagaagat gacaaaaaga aaaaagagaa agaggaagct gaacggatgc
3181 ttcaagacga tgatgatact gtgcaccttc catttgaagg gggaagtctc ttgcaaattc
3241 cagtcaaggc cctaaaatat agtcctgata aacctgtgag tgtgaaaata agttttgaag
3301 atgaaccaag aaagaaatac gtggatgctg aaacttcatt atagaattga accaagaggc
3361 attatacata tagatatata catatgtaat gtgtgcgtat catgtcacta tatataagaa
3421 tattgtatgt catgctgttt atgtgtgact accgggtttt taaaagtagt gtctggagtt
3481 tgtaatgagc accgtggaga ctatgtattt aatgaaatgc tctctttgaa gtgaggtaca
3541 tggttcttaa ctattcaaat atttattctg ttagaaaaaa aaaattttct gttttgcaat
3601 agaaggatgt ggagaaatgc tttcagtcta cttttcttaa atctctgttc atcagtggca
3661 attcgtaaaa accttaagtg atactttgtt tatatgttta taatttttag gtgtttcctg
3721 aaattttcac atattatttc acttttgtta gtgctttatg ggaagaatag ggagtctata
3781 ccagtgctgt gggaaaaatg gtaacatttc agggcttctc tatttgtgtt tcatttctgt
3841 agatgtccat cgtgtttcac taactggcgt tttcttagcc atagagatga ctgtagaaca
3901 atagaaactt taataatgat agtttttaac ttttatgttt aaattttttt taaatcttaa
3961 aaccttcata tctaggtatc cattgtgaca gacaagtaaa attgcaggtg atttgataat
4021 taagcaccca taccatttat aacttctgaa tttaaaaagt tatacaatgc cagtttgcaa
4081 tagttgattt tgatgccttt gtagaatatt ttttctgaat ccttatgctc ttttaaagcc
4141 aatgattccc actctgttct ctgccttgtc tctctttgtc ttaaaatgct ttagtttcca
4201 tcaggttcaa gttcttgact attattctct tataagtagt aggcgtaaat aatcaggagt
4261 tagaattctc tcagaagggt ctatgatcag tattacttta ttaagaatta cctttcattt
4321 tctctttatg ttattctttc acttttgtag attacattta atagcttgtt acctgtgatt
4381 ttattttaaa atatttattt tgatatgatg cttaaatatt atataaacat ttggaaaagt
4441 aacaaataga gtaaattgtt aatgtaaata gttggtgctt actttcattt atgtttatta
4501 tcttaaagca attgatagat tttacatctt tgatataaag cactgccata tttatatttt
4561 aaaaggaaat tagacatttt atatgtagct cagattaatg acatttttat tttgtgtatt
4621 agtttttgct tttctgagct ttttaaagtc taacaaatct ttttagtcat cttttatata
4681 cttttagttc cacatgaaat aaatgttgtt aagcctgtag gactggatga atggggttgt
4741 gaaactgatt tgacaagaga ataatttaca aaaatcaaat gagtattgag aagccacaga
4801 aatatcaaaa atggtgacat cactattagg atgaaaattt tatgaaattc caatgctccc
4861 tttaaccata taattaaatt acaaaggtat acataattaa tctaataaag gatcatgagg
4921 aatgccaaaa gctgaaattt tagcaagtct ggtgttttaa attcattata aactatttat
4981 taactaatgt aatgtcctcc tctaagacca tattgtaaga gtcttgttaa aatgatggat
5041 tcaacttctg cctcggatga gaggttggaa atgtagctgc ttttctttag aaaatatgta
5101 gctgtcatca tttggtactg cctaaaaaga gttagactct attggcaatt gatagagtat
5161 tacccacggt gcttattatt gtttatgagc ttccattgta atgattcctt tttatttgta
5221 gcagcataat tatttccaaa gaccccagta tttgctgcta tttttaaaac tcccctgatg
5281 tacctgaaca agaggatttc ctcacatcat ttccttgtgt ctggacatca ggggtaacaa
5341 ctgtacttac tttacaggaa gaaattttaa aactgaaaac tacctgggat catagtgttt
5401 ctgtgatttt atttaattgt gtatagtaat tatccagtgc cagaaaaacc gtcacttgca
5461 aaatactttg cactcaaaat gtttttacaa tgcttctaaa tgttactggt ttctgctttc
5521 ttttgactac ttgactgaca aaatgatctg actactccat ttaagagcaa aggtaactca
5581 tgtttaagta attaactgct tgttttaagt gattatattt cttccactgt ttttgaaaaa
5641 taatcaaaga tagcattcat tgagagacag tgacagatat aatttactac atatattgat
5701 ttttaaataa agttgcctta aataagtgta tgtaagcagt agtagttgct atgtactgat
5761 ttacctcaag gtgcaaaata attaaacctg tacatattcc atttacaaaa taaattcagc
5821 cctgcacttt ctttagatgc cttgatttcc agaatggagc ttagtgctac tgaataccct
5881 ggccacagag ccacctcagg atattctttt ctccacccta gtttatttat ttatagatat
5941 ctgtttacaa agtctgtagt aaatcctgat gctgaccatc tgaaatgtac tttttttctg
6001 aatgctgttt caatctaaaa tagcagcttt tgagaaaaca atgatgtaaa ttccttatga
6061 taaaaggatg attctatata ttctttaatg atattaaata tgccgaagcc aagcacacag
6121 tctttctaaa gtgtgtgtat gtttgtgtga atgtgaatga tactgatctt atatctgtta
6181 aaagttgttt taaaaagctg tggcatccca ttgttcatat ttgccaagtc ttctgtaaag
6241 atgtctagga cgaaatattt tatgtgctaa tgcatgtatt tgtaaaccag atttgtttac
6301 cactcaaaat taacttgttt tcttcatcca aaaaagttta tgtcttccac gtacttaaat
6361 tttctgtgtg ggtataatat agctttctaa tttttttctt tcacaaaggc aggttcaaaa
6421 ttctgttgaa agaaaaatgc tttctgaaac tgaggtataa caccagagct tgctgtttaa
6481 aggattatat gatgtacatc agttctataa atgtgctcag cagtttaaca tgtgaatcct
6541 gttttaaagt gctcagattt caactgtgta agccattgat ataacgctgt aattaaaaat
6601 gtttatatga aataacttaa tgttttaaat ttatttatgt agatcacatc atttttatca
6661 gtatgcagtg caaatatgtg aaatgtcttt tggtttattc caacaattat ttattttaga
6721 aagtaagttt aaagacttta aggacattca aagtttaaaa tagtgttcaa attgcaaaat
6781 ttggcaatct tcatataaat tggtttcttt tctaactttt caaaaactaa cattaaatgt
6841 caattatagg aaaacatagt tggaaatgta atcatcccaa agatcatttt taaaatgaaa
6901 tttaattagc acatattgaa catttgactt aattgttaaa ccccagtttt gttttgtttt
6961 tttaatcaga tttttgcaca ctgattagtt tttgtgttgt ggcttttgtt gctttattat
7021 tcaaggtttt tttttttctt tccccatggg ggagattgtc ttccaatgtt taactacgtt
7081 taaataaata aaaattgaat tttattgttc atttatataa aatctgatac cttgatgtaa
7141 tttcacaata cagttccaat ttttatggct tttataatta caatgatatt ttcttctata
7201 ataaaatcca aagtaaacat ttaaattgta gaactgatat ttttcattta tatgaagtat
7261 aagcctctac tgggtctata ttgtgaatca tcctgccttt caaatttgtt tcataattgt
7321 tagatgaaaa ctattttttt ggagatgtta ctgaagttga ttgagcaata aaagtctact
7381 taattaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//