LOCUS AF088916 3431 bp mRNA linear HUM 04-JUL-1999
DEFINITION Homo sapiens emilin precursor, mRNA, complete cds and 3' UTR.
ACCESSION AF088916
VERSION AF088916.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3431)
AUTHORS Doliana,R., Mongiat,M., Bucciotti,F., Giacomello,E., Deutzmann,R.,
Volpin,D., Bressan,G.M. and Colombatti,A.
TITLE EMILIN, a component of the elastic fiber and a new member of the
C1q/tumor necrosis factor superfamily of proteins
JOURNAL J. Biol. Chem. 274 (24), 16773-16781 (1999)
PUBMED 10358019
REFERENCE 2 (bases 1 to 3431)
AUTHORS Doliana,R., Mongiat,M., Bucciotti,F. and Colombatti,A.
TITLE Direct Submission
JOURNAL Submitted (31-AUG-1998) Experimental Oncology 2, Oncology Reference
Center, Pedemontana Occidentale, Aviano, Pordenone 33081, Italy
FEATURES Location/Qualifiers
source 1..3431
/db_xref="H-InvDB:HIT000068141"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..3051
/note="C1q protein family member"
/codon_start=1
/product="emilin precursor"
/protein_id="AAD42161.1"
/translation="MAPRTLWSCYLCCLLTAAAGAASYPPRGFSLYTGSSGALSPGGP
QAQIAPRPASRHRNWCAYVVTRTVSCVLEDGVETYVKYQPCAWGQPQCPQSIMYRRFL
RPRYRVAYKTVTDMEWRCCQGYGGDDCAESPAPALGPASSTPRPLARPARPNLSGSSA
GSPLSGLGGEGPGESEKVQQLEEQVQSLTKELQGLRGVLQGLSGRLAEDVQRAVETAF
NGRQQPADAAARPGVHETLNEIQHQLQLLDTRVSTHDQELGHLNNHHGGSSSSGGSRA
PAPASAPPGPSEELLRQLEQRLQESCSVCLAGLDGFRRQQQEDRERLRAMEKLLASVE
ERQRHLAGLAVGRRPPQECCSPELGRRLAELERRLDVVAGSVTVLSGRRGTELGGAAG
QGGHPPGYTSLASRLSRLEDRFNSTLGPSEEQEESWPGAPGGLSHWLPAARGRLEQLG
GLLANVSGELGGRLDLLEEQVAGAMQACGQLCSGAPGEQDSQVSEILSALERRVLDSE
GQLRLVGSGLHTVEAAGEARQATLEGLQEVVGRLQDRVDAQDETAAEFTLRLNLTAAR
LGQLEGLLQAHGDEGCGACGGVQEELGRLRDGVERCSCPLLPPRGPGAGPGVGGPSRG
PLDGFSVFGGSSGSALQALQGELSEVILSFSSLNDSLNELQTTVEGQGADLADLGATK
DRIISEINRLQQEATEHATESEERFRGLEEGQAQAGQCPSLEGRLGRLEGVCERLDTV
AGGLQGLREGLSRHVAGLWAGLRETNTTSQMQAALLEKLVGGQAGLGRRLGALNSSLQ
LLEDRLHQLSLKDLTGPAGEAGPPGPPGLQGPPGPAGPPGSPGKDGQEGPIGPPGPQG
EQGVEGAPAAPVPQVAFSAALSLPRSEPGTVPFDRVLLNDGGYYDPETGVFTAPLAGR
YLLSAVLTGHRHEKVEAVLSRSNQGVARVDSGGYEPEGLENKPVAESQPSPGTLGVFS
LILPLQAGDTVCVDLVMGQLAHSEEPLTIFSGALLYGDPELEHA"
sig_peptide 1..63
mat_peptide 64..3048
/product="emilin"
misc_feature 160..387
/note="similar to multimerin"
misc_feature 1906..2115
/inference="non-experimental evidence, no additional
details recorded"
/note="encodes coiled-coil"
misc_feature 2166..2275
/inference="non-experimental evidence, no additional
details recorded"
/note="encodes leucine-zipper"
misc_feature 2335..2421
/inference="non-experimental evidence, no additional
details recorded"
/note="encodes leucine-zipper"
misc_feature 2439..2592
/inference="non-experimental evidence, no additional
details recorded"
/note="encodes collagen structure"
misc_feature 2596..3048
/note="C1q-like domain"
3'UTR 3052..3431
regulatory 3410..3415
/regulatory_class="polyA_signal_sequence"
BASE COUNT 575 a 1087 c 1237 g 532 t
ORIGIN
1 atggcccccc gcaccctctg gagctgctac ctctgctgcc tgctgacggc agctgcaggg
61 gccgccagct accctcctcg aggtttcagc ctctacacag gttccagtgg ggccctcagc
121 cccggggggc cccaggccca gattgccccc cggccagcca gccgccacag gaactggtgt
181 gcctacgtgg tgacccggac agtgagctgt gtccttgagg atggagtgga gacatatgtc
241 aagtaccagc cttgtgcctg gggccagccc cagtgtcccc aaagcatcat gtaccgccgc
301 ttcctccgcc ctcgctaccg tgtggcctac aagacagtga ccgacatgga gtggaggtgc
361 tgtcagggtt atgggggcga tgactgtgct gagagtcccg ctccagcgct ggggcctgcg
421 tcttccacac cacggcccct ggcccggcct gcccgcccca acctctctgg ctccagtgca
481 ggcagccccc tcagtggact ggggggagaa ggtcctgggg agtcagagaa ggtgcagcag
541 ctggaggaac aggtgcagag cctgaccaag gagctgcaag gcctgcgggg cgtcctgcaa
601 ggactgagcg ggcgcctggc agaggatgtg cagagggctg tggagacggc cttcaacggg
661 aggcagcagc cagctgacgc ggctgcccgc cctggggtgc atgaaaccct caatgagatc
721 cagcaccagc tgcagctcct ggacacccgc gtctccaccc acgaccagga gctgggtcac
781 ctcaacaacc atcatggcgg cagcagcagc agtgggggca gcagggcccc agccccagcc
841 tcagcccctc cgggccccag tgaggagctg ctgcggcagc tggagcagcg gttgcaggag
901 tcctgctccg tgtgcctggc cgggctagat ggcttccgcc ggcagcagca ggaggacagg
961 gagcggctgc gagcgatgga gaagctgctg gcctcggtgg aggagcggca acggcacctc
1021 gcagggctgg cggtgggccg caggccccct caggaatgct gctctccaga gctgggccgg
1081 cgactggcag agctggagcg caggctggat gtcgtggccg gctcagtgac agtgctgagt
1141 gggcggcgag gcacagagct gggaggagcc gcggggcagg gaggccaccc cccaggctac
1201 accagcttgg cctcccgcct gtctcgcctg gaggaccgct tcaactccac cctgggccct
1261 tcggaggagc aggaggagag ctggcctggg gctcctgggg ggctgagcca ctggctgcct
1321 gctgcccggg gccgactaga gcagttgggg gggctgctgg ccaatgtgag cggggagctg
1381 ggggggcggt tggatctgtt ggaggagcag gtggcagggg ccatgcaggc atgcgggcag
1441 ctctgctctg gggcccctgg ggagcaggac tctcaagtca gcgagatcct cagtgccttg
1501 gagcgcaggg tgctggacag tgaggggcag ctgcggctgg tgggctccgg cctgcacacg
1561 gtggaagcag cgggggaggc ccggcaggcc acgctggagg gattacaaga ggttgtgggc
1621 cggctccagg atcgtgtgga tgcccaggat gagacagctg cagagttcac actacggctg
1681 aatctcactg cggcccggct aggccaactg gaggggctgc tgcaggccca tggggatgag
1741 ggctgtgggg cctgtggcgg agtccaagag gaactaggcc gccttcggga tggtgtggag
1801 cgctgctcct gccccctgtt gcctcctcgg ggtcctgggg ctggtccagg tgttgggggc
1861 ccaagccgtg ggcccctgga cggcttcagc gtgtttgggg gcagctcagg ctcagccctg
1921 caggccctgc aaggagagct ctctgaggtt attctcagct tcagctccct caatgactca
1981 ctgaatgagc tccagaccac tgtggagggc cagggcgctg atctggctga cctgggggca
2041 accaaggacc gtatcatttc tgagattaac aggctgcagc aggaggccac agagcatgct
2101 acagagagtg aagagcgctt ccgaggccta gaggagggac aagcacaggc cggccagtgc
2161 cccagcttag aggggcgatt gggccgtctt gagggtgtct gtgaacggtt ggacactgtg
2221 gctgggggac tgcagggcct gcgcgagggc ctttccagac acgtggctgg gctctgggct
2281 gggctccggg aaaccaacac caccagccag atgcaggcag ccctgctgga gaagctggtc
2341 gggggacagg cgggcctggg caggcggctg ggtgccctta acagctccct gcagctcctg
2401 gaggaccgtc tgcaccagct cagcctgaag gacctcactg ggcctgcagg agaggctggg
2461 cccccagggc ctcctgggct gcagggaccc ccaggccctg ctggacctcc aggatcacca
2521 ggcaaggacg ggcaagaggg ccccatcggg ccaccaggtc ctcaagggga acagggagtg
2581 gagggggcac cagcagcccc tgtgccccaa gtggcatttt cagctgctct gagtttgccc
2641 cggtctgaac caggcacggt ccccttcgac agagtcctgc tcaatgatgg aggctattat
2701 gatccagaga caggcgtgtt cacagcgcca ctggctggac gctacttgct gagcgcggtg
2761 ctgactgggc accggcacga gaaagtggag gccgtgctgt cccgctccaa ccagggcgtg
2821 gcccgcgtag actccggtgg ctacgagcct gagggcctgg agaataagcc ggtggccgag
2881 agccagccca gcccgggcac cctgggcgtc ttcagcctca tcctgccgct gcaggccggg
2941 gacacggtct gcgtcgacct ggtcatgggg cagctggcgc actcggagga gccgctcacc
3001 atcttcagcg gggccctgct ctatggggac ccagagcttg aacacgcgta gactggggtc
3061 ccgcccgacg tgtctacgtc ggctgaagag acagcggggg cggcgggctc ctggggtctc
3121 gcctgagacg gggcacctag ccctgggcga gcgccgcacc cgggcccgca gcggcaccgc
3181 gcccagagcg gcctctcccc acgcccgggg cgcgccggct cagggaggct cggggccgcc
3241 catgcagact tttggcctgg cgcgatcccc caagaacccc tccagggccg gcctgcggag
3301 gagccgatcc tcgcaccctc cgctccctcc actggccctc caggtcgatt ccctgggctc
3361 caggctcccc cgcgcgggcg ccgcccaccg ccatactaaa cgatcgagga ataaagacac
3421 ttggtttttc t
//