LOCUS AF087661 1475 bp mRNA linear HUM 26-JAN-1999
DEFINITION Homo sapiens NADH-ubiquinone oxidoreductase 42 kDa subunit mRNA,
complete cds, nuclear gene encoding mitochondrial protein.
ACCESSION AF087661
VERSION AF087661.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1475)
AUTHORS Loeffen,J.L., Triepels,R.H., van den Heuvel,L.P., Schuelke,M.,
Buskens,C.A., Smeets,R.J., Trijbels,J.M. and Smeitink,J.A.
TITLE cDNA of eight nuclear encoded subunits of NADH:ubiquinone
oxidoreductase: human complex I cDNA characterization completed
JOURNAL Biochem. Biophys. Res. Commun. 253 (2), 415-422 (1998)
PUBMED 9878551
REFERENCE 2 (bases 1 to 1475)
AUTHORS Triepels,R., Loeffen,J., van den Heuvel,B., Schuelke,M.,
Buskens,C., Smeets,R., Trijbels,F. and Smeitink,J.
TITLE Direct Submission
JOURNAL Submitted (28-AUG-1998) Nijmegen Center for Mitochondrial
Disorders, University Hospital Nijmegen, P.O. Box 9101, Nijmegen,
Gelderland 6500HB, Netherlands
FEATURES Location/Qualifiers
source 1..1475
/db_xref="H-InvDB:HIT000067487"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
5'UTR <1..21
CDS 22..1089
/note="complex I subunit; NDUFA10 subunit"
/codon_start=1
/product="NADH-ubiquinone oxidoreductase 42 kDa subunit"
/protein_id="AAD09755.1"
/translation="MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFL
LGDKASKRLTERSRVITVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGK
PLATDYNGNCSLEKFYDDPRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLE
RSIFSDFVFLEAMYNQGFIRKQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRI
QKKGDPHEMKITSAYLQDIENAYKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYL
KFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFREL
PGRKYSPGYNTEVGDKWIWLK"
3'UTR 1090..1465
regulatory 1446..1451
/regulatory_class="polyA_signal_sequence"
polyA_site 1466
BASE COUNT 396 a 342 c 397 g 340 t
ORIGIN
1 tcctgagctg accgggtagc catggccttg cggctcctga agctggcagc gacgtccgcg
61 tccgcccggg tcgtggcggc gggcgcccag cgcgtgagag gaattcatag cagtgtgcag
121 tgcaagctgc gctatggaat gtggcatttc ctacttgggg ataaagcaag caaaagactg
181 acagaacgca gcagagtgat aactgtagat ggcaatatat gtactggaaa aggcaaactt
241 gcaaaagaaa tagcagagaa actaggcttc aagcactttc ctgaagcggg gattcattat
301 ccagacagta ccacaggaga tgggaagccc ctcgccaccg actataatgg caactgtagt
361 ttggagaaat tttacgatga tccgagaagc aatgatggca acagttaccg cctgcagtcc
421 tggttgtaca gcagtcgcct gctgcagtac tcagatgcct tggagcactt gctgaccaca
481 ggacaaggtg ttgtgttgga gcgctccatc ttcagtgact ttgtgttcct ggaggcgatg
541 tacaaccagg gattcatccg aaagcagtgt gtggaccact acaacgaggt gaagagcgtc
601 accatctgcg attacctgcc cccccacctg gtgatttaca tcgatgtgcc cgttccagag
661 gtccagaggc ggattcagaa gaaaggagat ccacatgaaa tgaagatcac ctctgcctat
721 ctacaggaca ttgagaatgc ctataagaaa acctttctcc ctgagatgag tgaaaaatgt
781 gaggttttac agtattctgc aagggaagct caagattcaa aaaaggtggt agaggacatt
841 gaatacctga agttcgataa agggccgtgg ctcaagcagg acaatcgcac tttataccac
901 ctgcgattac tggttcagga taagtttgag gtgctgaatt acacaagcat tcctatcttt
961 ctcccggaag tcaccattgg agctcatcag actgaccgtg tcttacatca gttcagagag
1021 ctgccgggcc gcaagtacag ccctgggtac aacaccgagg tgggagacaa gtggatctgg
1081 ctgaagtgaa cgggccgcct tctgctccag ctgcatcaca gtgatggcca agctgcatca
1141 gccgcactct cctggacgcc atatagcttt aagatcgggg gagggtaaat aatgcaaaaa
1201 ttgcacagtg gaagaagggg tctcacaaaa agcaatccat cctgtagtat aggtaatgga
1261 gttgggggaa gcagcttcca ttctggatgt ttggaaccct ttagctttgt tttggaatgg
1321 cccaccattc tcactggaaa acagtggtct gctgtgaaag gccagctctc ggcagcccct
1381 gtggtttcag cgtgccgctc tgtgtcattc aggttgtgca cattgttttt cttctgactt
1441 ccagaaataa aagtgtttcc atgggaaaaa aaaaa
//