LOCUS AF084645 2870 bp mRNA linear HUM 15-NOV-2016
DEFINITION Homo sapiens orphan nuclear receptor (PAR1) mRNA, complete cds.
ACCESSION AF084645
VERSION AF084645.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2870)
AUTHORS Bertilsson,G., Heidrich,J., Svensson,K., Asman,M., Jendeberg,L.,
Sydow-Backman,M., Ohlsson,R., Postlind,H., Blomquist,P. and
Berkenstam,A.
TITLE Identification of a human nuclear receptor defines a new signaling
pathway for CYP3A induction
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (21), 12208-12213 (1998)
PUBMED 9770465
REFERENCE 2 (bases 1 to 2870)
AUTHORS Bertilsson,G., Asman,M., Blomquist,P. and Berkenstam,A.
TITLE Direct Submission
JOURNAL Submitted (19-AUG-1998) Cell and Molecular Biology, Medical Nobel
Institute, Karolinska Institute, Doktorsringen2, Stockholm 17177,
Sweden
REFERENCE 3 (bases 1 to 2870)
AUTHORS Bertilsson,G., Asman,M., Blomquist,P. and Berkenstam,A.
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2016) Cell and Molecular Biology, Medical Nobel
Institute, Karolinska Institute, Doktorsringen2, Stockholm 17177,
Sweden
REMARK Sequence update by database staff to remove vector contamination
COMMENT On Nov 15, 2016 this sequence version replaced AF084645.1.
FEATURES Location/Qualifiers
source 1..2870
/db_xref="H-InvDB:HIT000066643"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="liver"
gene 1..2870
/gene="PAR1"
CDS 245..1549
/gene="PAR1"
/codon_start=1
/product="orphan nuclear receptor"
/protein_id="AAC64558.1"
/translation="MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVC
GDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKC
LESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK
TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGE
DGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLL
KGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQ
LHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLK
IMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS"
BASE COUNT 756 a 721 c 769 g 624 t
ORIGIN
1 ggacgggaag aggaagcact gcctttactt cagtgggaat ctcggcctca gcctgcaagc
61 caagtgttca cagtgaaaaa agcaagagaa taagctaata ctcctgtcct gaacaaggca
121 gcggctcctt ggtaaagcta ctccttgatc gatcctttgc accggattgt tcaaagtgga
181 ccccagggga gaagtcggag caaagaactt accaccaagc agtccaagag gcccagaagc
241 aaacctggag gtgagaccca aagaaagctg gaaccatgct gactttgtac actgtgagga
301 cacagagtct gttcctggaa agcccagtgt caacgcagat gaggaagtcg gaggtcccca
361 aatctgccgt gtatgtgggg acaaggccac tggctatcac ttcaatgtca tgacatgtga
421 aggatgcaag ggctttttca ggagggccat gaaacgcaac gcccggctga ggtgcccctt
481 ccggaagggc gcctgcgaga tcacccggaa gacccggcga cagtgccagg cctgccgcct
541 gcgcaagtgc ctggagagcg gcatgaagaa ggagatgatc atgtccgacg aggccgtgga
601 ggagaggcgg gccttgatca agcggaagaa aagtgaacgg acagggactc agccactggg
661 agtgcagggg ctgacagagg agcagcggat gatgatcagg gagctgatgg acgctcagat
721 gaaaaccttt gacactacct tctcccattt caagaatttc cggctgccag gggtgcttag
781 cagtggctgc gagttgccag agtctctgca ggccccatcg agggaagaag ctgccaagtg
841 gagccaggtc cggaaagatc tgtgctcttt gaaggtctct ctgcagctgc ggggggagga
901 tggcagtgtc tggaactaca aacccccagc cgacagtggc gggaaagaga tcttctccct
961 gctgccccac atggctgaca tgtcaaccta catgttcaaa ggcatcatca gctttgccaa
1021 agtcatctcc tacttcaggg acttgcccat cgaggaccag atctccctgc tgaagggggc
1081 cgctttcgag ctgtgtcaac tgagattcaa cacagtgttc aacgcggaga ctggaacctg
1141 ggagtgtggc cggctgtcct actgcttgga agacactgca ggtggcttcc agcaacttct
1201 actggagccc atgctgaaat tccactacat gctgaagaag ctgcagctgc atgaggagga
1261 gtatgtgctg atgcaggcca tctccctctt ctccccagac cgcccaggtg tgctgcagca
1321 ccgcgtggtg gaccagctgc aggagcaatt cgccattact ctgaagtcct acattgaatg
1381 caatcggccc cagcctgctc ataggttctt gttcctgaag atcatggcta tgctcaccga
1441 gctccgcagc atcaatgctc agcacaccca gcggctgctg cgcatccagg acatacaccc
1501 ctttgctacg cccctcatgc aggagttgtt cggcatcaca ggtagctgag cggctgccct
1561 tgggtgacac ctccgagagg cagccagacc cagagccctc tgagccgcca ctcccgggcc
1621 aagacagatg gacactgcca agagccgaca atgccctgct ggcctgtctc cctagggaat
1681 tcctgctatg acagctggct agcattcctc aggaaggaca tgggtgcccc ccacccccag
1741 ttcagtctgt agggagtgaa gccacagact cttacgtgga gagtgcactg acctgtaggt
1801 caggaccatc agagaggcaa ggttgccctt tccttttaaa aggccctgtg gtctggggag
1861 aaatccctca gatcccacta aagtgtcaag gtgtggaagg gaccaagcga ccaaggatag
1921 gccatctggg gtctatgccc acatacccac gtttgttcgc ttcctgagtc ttttcattgc
1981 tacctctaat agtcctgtct cccacttccc actcgttccc ctcctcttcc gagctgcttt
2041 gtgggctcaa ggcctgtact catcggcagg tgcatgagta tctgtgggag tcctctagag
2101 agatgagaag ccaggaggcc tgcaccaaat gtcagaagct tggcatgacc tcattccggc
2161 cacatcattc tgtgtctctg catccatttg aacacattat taagcactga taataggtag
2221 cctgctgtgg ggtatacagc attgactcag atatagatcc tgagctcaca gagtttatag
2281 ttaaaaaaac aaacagaaac acaaacaatt tggatcaaaa ggagaaaatg ataagtgaca
2341 aaagcagcac aaggaatttc cctgtgtgga tgctgagctg tgatggcagg cactgggtac
2401 ccaagtgaag gttcccgagg acatgagtct gtaggagcaa gggcacaaac tgcagctgtg
2461 agtgcgtgtg tgtgatttgg tgtaggtagg tctgtttgcc acttgatggg gcctgggttt
2521 gttcctgggg ctggaatgct gggtatgctc tgtgacaagg ctacgctgac aatcagttaa
2581 acacaccgga gaagaaccat ttacatgcac cttatatttc tgtgtacaca tctattctca
2641 aagctaaagg gtatgaaagt gcctgccttg tttatagcca cttgtgagta aaaatttttt
2701 tgcattttca caaattatac tttatataag gcattccaca cctaagaact agttttggga
2761 aatgtagccc tgggtttaat gtcaaatcaa ggcaaaagga attaaataat gtacttttgg
2821 ctaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//