LOCUS AF084558 4205 bp mRNA linear HUM 12-OCT-2000
DEFINITION Homo sapiens fatty acid desaturase 1 (FADS1) mRNA, complete cds.
ACCESSION AF084558
VERSION AF084558.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4205)
AUTHORS Marquardt,A., Stohr,H., White,K. and Weber,B.H.
TITLE cDNA cloning, genomic structure, and chromosomal localization of
three members of the human fatty acid desaturase family
JOURNAL Genomics 66 (2), 175-183 (2000)
PUBMED 10860662
REFERENCE 2 (bases 1 to 4205)
AUTHORS Marquardt,A., Stoehr,H., Passmore,L.A., Kraemer,F., Rivera,A. and
Weber,B.H.F.
TITLE Direct Submission
JOURNAL Submitted (05-AUG-1998) Institute of Human Genetics, University of
Wuerzburg, Biozentrum, Am Hubland, Wuerzburg D-97074, Germany
FEATURES Location/Qualifiers
source 1..4205
/db_xref="H-InvDB:HIT000066639"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q12-q13.1"
gene 1..4205
/gene="FADS1"
misc_feature 1..181
/gene="FADS1"
/note="similar to EST zk09h08.r1 denoted in GenBank
Accession Number AA029030"
5'UTR 1..78
/gene="FADS1"
CDS 79..1413
/gene="FADS1"
/codon_start=1
/product="fatty acid desaturase 1"
/protein_id="AAG23120.1"
/translation="MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYN
ISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEP
TKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPF
LLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQ
HHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLP
LYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWF
VWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMP
RHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ"
3'UTR 1414..4205
/gene="FADS1"
regulatory 4182..4187
/regulatory_class="polyA_signal_sequence"
/gene="FADS1"
BASE COUNT 1139 a 1025 c 1003 g 1037 t
ORIGIN
1 cactcctgga gcccgcggac cccgagcacg cgcctgacag cccctgctgg cccggcgcgc
61 ggcgtcgcca ggccagctat ggcccccgac ccggtggccg ccgagaccgc ggctcaggga
121 cctaccccgc gctacttcac ctgggacgag gtggcccagc gctcagggtg cgaggagcgg
181 tggctagtga tcgaccgtaa ggtgtacaac atcagcgagt tcacccgccg gcatccaggg
241 ggctcccggg tcatcagcca ctacgccggg caggatgcca cggatccctt tgtggccttc
301 cacatcaaca agggccttgt gaagaagtat atgaactctc tcctgattgg agaactgtct
361 ccagagcagc ccagctttga gcccaccaag aataaagagc tgacagatga gttccgggag
421 ctgcgggcca cagtggagcg gatggggctc atgaaggcca accatgtctt cttcctgctg
481 tacctgctgc acatcttgct gctggatggt gcagcctggc tcaccctttg ggtctttggg
541 acgtcctttt tgcccttcct cctctgtgcg gtgctgctca gtgcagttca ggcccaggct
601 ggctggctgc agcatgactt tgggcacctg tcggtcttca gcacctcaaa gtggaaccat
661 ctgctacatc attttgtgat tggccacctg aagggggccc ccgccagttg gtggaaccac
721 atgcacttcc agcaccatgc caagcccaac tgcttccgca aagacccaga catcaacatg
781 catcccttct tctttgcctt ggggaagatc ctctctgtgg agcttgggaa acagaagaaa
841 aaatatatgc cgtacaacca ccagcacaaa tacttcttcc taattgggcc cccagccttg
901 ctgcctctct acttccagtg gtatattttc tattttgtta tccagcgaaa gaagtgggtg
961 gacttggcct ggatgattac cttctacgtc cgcttcttcc tcacttatgt gccactattg
1021 gggctgaaag ccttcctggg ccttttcttc atagtcaggt tcctggaaag caactggttt
1081 gtgtgggtga cacagatgaa ccatattccc atgcacattg atcatgaccg gaacatggac
1141 tgggtttcca cccagctcca ggccacatgc aatgtccaca agtctgcctt caatgactgg
1201 ttcagtggac acctcaactt ccagattgag caccatcttt ttcccacgat gcctcgacac
1261 aattaccaca aagtggctcc cctggtgcag tccttgtgtg ccaagcatgg catagagtac
1321 cagtccaagc ccctgctgtc agccttcgcc gacatcatcc actcactaaa ggagtcaggg
1381 cagctctggc tagatgccta tcttcaccaa taacaacagc caccctgccc agtctggaag
1441 aagaggagga agactctgga gccaaggcag aggggagctt gagggacaat gccactatag
1501 tttaatactc agagggggtt gggtttgggg acataaagcc tctgactcaa actcctccct
1561 tttatcttct agccacagtt ctaagaccca aagtgggggg tggacacaga agtccctagg
1621 agggaaggag ctgttggggc aggggtgtaa attatttcct ttttctagtt tggcacatgc
1681 aggtagttgg tgaacagaga gaaccaggag ggtaacagaa gaggagggac ctactgaacc
1741 cagagtcagg aagagattta acactaaaat tccactcatg ccgggcgtgg tgcacgcgcc
1801 tgtaatccca gctacccagg aggctgaggc aggagaatcg cttgaaccgg ggaggtggag
1861 gttgcagtga gctgagatca cgccattgta ctccagcctg ggcgacagag caagactcca
1921 tttcaaaaaa aaaaaaaaaa aaaaaaatcc actcatataa aaggtgagct cagctcactg
1981 gtccatttct cagtggcttc tccatcctca tttgcaaacc tcagagggat aaggcagttg
2041 aacctgatga gcaagaatta taacagcaag gaaacattaa tgcttagaat tctgagatcc
2101 agcacaactc agtctgtggg agctcagctc gctgcccagg gataggtatg acctatgtct
2161 gccttaggct gctgggagat gccattctcc agtttcagaa gcaggcaggg caaaggtcaa
2221 gactgtggta ttggggtctt ttggctctga aggatcctgg aaccactgat tttggtttat
2281 tccctccagg gtctaaagag aacaagaggt gctagctctt accaaaacag atggtagaga
2341 gagttgctgg ctatttaaaa agctctttca tcttttaatt cacctcttct tttcacctct
2401 ttaaccactc ctcaggaaca gaacacttct aggactgggg gtcttttagc tccataagca
2461 agtgagcaga tgggacaagt tagtcttttc tccctagaaa caaaggggat gcccagtggt
2521 ttccctttgc ttcccaacct aaaatttcaa gtttaataaa atagcaatta gcagaagtga
2581 ccaaattggg agataattat cagtcatgag gaaagacaca gatttcggtc ataaagaatg
2641 taagggctat aagtagaaac tttctataac ctaaatgatg ttatagaatt atttttgagc
2701 aggagcagaa agattaaata tgatcacttc atacttctaa atcagaaata ggaagattaa
2761 aaccacagaa cagtttgtga tttctattgc tggtagctag gtatcttact ctgtccactc
2821 ttgttcaagt atctaactct tctggaaacc aaataggctt tagaagagat tatcctatat
2881 tcctatcagt ataatactaa aatgtaactt tttaatcatc tggtttttaa aagataaaca
2941 gtttagccca tctctccaga gagcaaacat aggaatatga ctcaggagcc tcctagggct
3001 tatcatcagc cctcacaccc gcttccccct ccaacccaca gcctttgctt ccaggtggca
3061 ggattactac tttgcctctt cagcagcatc tactctaggc atattgatca ttttagacac
3121 tgggagaaga gaacctcaaa ctaggaggaa aagacagagc ctccacttag ttttgggagg
3181 ggatggcaga cagtcaagga gatgagcgtc ctaaggcatg ttgggatagg gtcagatgca
3241 ccacccatgg agaggtttgt caacacaaag acatggaagg ttagaggttt gtcaacaaaa
3301 agacatggaa ggttaggttt gtcaacacaa agacatggaa gattagaggt ttgtcaacac
3361 aaagatacag gaagaatggg ctgcagaaga tttagatgtt ttccatttgg gcacatttta
3421 cttagctgga gaactaggtt taaaacagcc tgggtaggaa aattagaagc aagctggatg
3481 cagtggctca tgcctgtaat cccaacactt ttgggaggtc caggcaggag gatcacttgg
3541 gcccaggagg tcaagcctgc agcgagctga gatcacacca ctgcactcca gcctggggtg
3601 atagaacaag accctgtctc aaaaaaaaaa aaaaacaaca aaaacttaga attgaggagt
3661 tgtacctcca ttggcttcct cactccaaaa taggtgctga tccttcctat tcctattctt
3721 tgccaccttt tgggtgtggt gtcaccagcc tgtttagcca agtagctttg ggcataggct
3781 gcccaatctg agcaaacacc agtgaggctc tattgagcaa gaccaagtcc tcaaagcacc
3841 tgaaccactg tggccttctc agcctacagc agtgtggtct cttacatggc cacaaaggga
3901 cacacagtga caaaaggctc ggaatgttac aatggtaaaa tgagtgatct caaatccact
3961 gacagatata aaataggctt agagaggaaa agctgcctct ggtcaagtag atcatggcag
4021 catgaattcc aactcacttt tttacgaact ccaacttcta tgtttatctt tgttactttc
4081 acttttttac aacctgncag aggcattttt taaatcaggc ccaatatcag tattcttttt
4141 gtgtgtgcca attttgttat cacatcccta tgaagttgaa aaataaagtt aattttgacc
4201 aaaag
//