LOCUS AF084199 2615 bp mRNA linear HUM 30-AUG-1998
DEFINITION Homo sapiens beta-interferon gene positive-regulatory domain I
binding factor (BLIMP1) mRNA, complete cds.
ACCESSION AF084199
VERSION AF084199.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2615)
AUTHORS Keller,A.D. and Maniatis,T.
TITLE Identification and characterization of a novel repressor of
beta-interferon gene expression
JOURNAL Genes Dev. 5 (5), 868-879 (1991)
PUBMED 1851123
REFERENCE 2 (bases 1 to 2615)
AUTHORS Ren,B., Chee,K.J., Keller,A.D. and Maniatis,T.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-1998) Molecular and Cellular Biology, Harvard
University, 7 Divinity Avenue, Cambridge, MA 02138, USA
FEATURES Location/Qualifiers
source 1..2615
/db_xref="H-InvDB:HIT000066616"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q21-q22.1"
gene 1..2615
/gene="BLIMP1"
CDS 224..2593
/gene="BLIMP1"
/function="transcription repressor"
/note="PRDI-BF1; similar to Mus musculus Blimp-1 protein
(B lymphocyte-induced muturation protein 1)"
/codon_start=1
/product="beta-interferon gene positive-regulatory domain
I binding factor"
/protein_id="AAC33300.1"
/translation="MKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAE
ASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRI
YSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQEL
LVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEIL
KLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKA
SLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEH
RDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAV
SSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE
VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSD
EAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERP
FKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQ
CKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGL
PLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSL
QRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP"
BASE COUNT 694 a 780 c 645 g 496 t
ORIGIN
1 gaattccggg aagccagacg gttaacacag acaaagtgct gccgtgacac tcggccctcc
61 agtgttgcgg agaggcaaga gcagcgaccg cgcacctgtc cgcccggagc tgggacgcgc
121 gcccgggcgg ccggacgaag cgaggaggga ccgccgaggc tgcccccaag tgtaactcca
181 gcactgtgag gtttcaggga ttggcagagg ggaccaaggg gacatgaaaa tggacatgga
241 ggatgcggat atgactctgt ggacagaggc tgagtttgaa gagaagtgta catacattgt
301 gaacgaccac ccctgggatt ctggtgctga tggcggtact tcggttcagg cggaggcatc
361 cttaccaagg aatctgcttt tcaagtatgc caccaacagt gaagaggtta ttggagtgat
421 gagtaaagaa tacataccaa agggcacacg ttttggaccc ctaataggtg aaatctacac
481 caatgacaca gttcctaaga acgccaacag gaaatatttt tggaggatct attccagagg
541 ggagcttcac cacttcattg acggctttaa tgaagagaaa agcaactgga tgcgctatgt
601 gaatccagca cactctcccc gggagcaaaa cctggctgcg tgtcagaacg ggatgaacat
661 ctacttctac accattaagc ccatccctgc caaccaggaa cttcttgtgt ggtattgtcg
721 ggactttgca gaaaggcttc actaccctta tcccggagag ctgacaatga tgaatctcac
781 acaaacacag agcagtctaa agcaaccgag cactgagaaa aatgaactct gcccaaagaa
841 tgtcccaaag agagagtaca gcgtgaaaga aatcctaaaa ttggactcca acccctccaa
901 aggaaaggac ctctaccgtt ctaacatttc acccctcaca tcagaaaagg acctcgatga
961 ctttagaaga cgtgggagcc ccgaaatgcc cttctaccct cgggtcgttt accccatccg
1021 ggcccctctg ccagaagact ttttgaaagc ttccctggcc tacgggatcg agagacccac
1081 gtacatcact cgctccccca ttccatcctc caccactcca agcccctctg caagaagcag
1141 ccccgaccaa agcctcaaga gctccagccc tcacagcagc cctgggaata cggtgtcccc
1201 tgtgggcccc ggctctcaag agcaccggga ctcctacgct tacttgaacg cgtcctacgg
1261 cacggaaggt ttgggctcct accctggcta cgcacccctg ccccacctcc cgccagcttt
1321 catcccctcg tacaacgctc actaccccaa gttcctcttg cccccctacg gcatgaattg
1381 taatggcctg agcgctgtga gcagcatgaa tggcatcaac aactttggcc tcttcccgag
1441 gctgtgccct gtctacagca atctcctcgg tgggggcagc ctgccccacc ccatgctcaa
1501 ccccacttct ctcccgagct cgctgccctc agatggagcc cggaggttgc tccagccgga
1561 gcatcccagg gaggtgcttg tcccggcgcc ccacagtgcc ttctccttta ccggggccgc
1621 cgccagcatg aaggacaagg cctgtagccc cacaagcggg tctcccacgg cgggaacagc
1681 cgccacggca gaacatgtgg tgcagcccaa agctacctca gcagcgatgg cagcccccag
1741 cagcgacgaa gccatgaatc tcattaaaaa caaaagaaac atgaccggct acaagaccct
1801 tccctacccg ctgaagaagc agaacggcaa gatcaagtac gaatgcaacg tttgcgccaa
1861 gactttcggc cagctctcca atctgaaggt ccacctgaga gtgcacagtg gagaacggcc
1921 tttcaaatgt cagacttgca acaagggctt tactcagctc gcccacctgc agaaacacta
1981 cctggtacac acgggagaaa agccacatga atgccaggtc tgccacaaga gatttagcag
2041 caccagcaat ctcaagaccc acctgcgact ccattctgga gagaaaccat accaatgcaa
2101 ggtgtgccct gccaagttca cccagtttgt gcacctgaaa ctgcacaagc gtctgcacac
2161 ccgggagcgg ccccacaagt gctcccagtg ccacaagaac tacatccatc tctgtagcct
2221 caaggttcac ctgaaaggga actgcgctgc ggccccggcg cctgggctgc ccttggaaga
2281 tctgacccga atcaatgaag aaatcgagaa gtttgacatc agtgacaatg ctgaccggct
2341 cgaggacgtg gaggatgaca tcagtgtgat ctctgtagtg gagaaggaaa ttctggccgt
2401 ggtcagaaaa gagaaagaag aaactggcct gaaagtgtct ttgcaaagaa acatggggaa
2461 tggactcctc tcctcagggt gcagccttta tgagtcatca gatctacccc tcatgaagtt
2521 gcctcccagc aacccactac ctctggtacc tgtaaaggtc aaacaagaaa cagttgaacc
2581 aatggatcct taagattttc agaaaacact tattt
//