LOCUS AF083500 1283 bp mRNA linear HUM 04-NOV-1998
DEFINITION Homo sapiens connective tissue growth factor-like protein
precursor, mRNA, complete cds.
ACCESSION AF083500
VERSION AF083500.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1283)
AUTHORS Kumar,S., Hand,A.T., Connor,J.C., Dodds,R.A., Ryan,P.J.,
Trill,J.G., Fisher,S.M., Slemmon,J.R., Lipshutz,D.B.,
Bartholomew,V., James,I.E., Rieman,D.J., Gowen,M. and Lee,J.C.
TITLE Identification and cloning of CTGF-L from human osteoblasts, a
novel cysteine rich protein containing an IGF binding domain
JOURNAL Bone 23 (5), S240 (1998)
REFERENCE 2 (bases 1 to 1283)
AUTHORS Kumar,S.
TITLE Direct Submission
JOURNAL Submitted (11-AUG-1998) Bone & Cartilage Biology, UW 2109,
SmithKline Beecham, 709 Swedeland Road, King of Prussia, PA 19406,
USA
FEATURES Location/Qualifiers
source 1..1283
/db_xref="H-InvDB:HIT000066584"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20q12-q13"
/cell_type="primary osteoblast"
CDS 9..761
/note="CTGF-L; encodes IGF binding (IGFB), Von Willebrand
factor type C (VWC) and thrombospondin type I (TSP1)
domains; member of the CCN (CTGF/cyr61/nov) family; lacks
the fourth carboxy-terminal domain present in other
members of the CCN family"
/codon_start=1
/product="connective tissue growth factor-like protein
precursor"
/protein_id="AAC70350.1"
/translation="MRGTPKTHLLAFSLLCLLSKVRTQLCPTPCTCPWPPPRCPLGVP
LVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEV
NGRLYREGETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPE
WVCGQGGGLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSN
QNRFCRLETQRRLCLSRPCPPSRGRSPQNSAF"
BASE COUNT 235 a 418 c 389 g 241 t
ORIGIN
1 caggggacat gagaggcaca ccgaagaccc acctcctggc cttctccctc ctctgcctcc
61 tctcaaaggt gcgtacccag ctgtgcccga caccatgtac ctgcccctgg ccacctcccc
121 gatgcccgct gggagtaccc ctggtgctgg atggctgtgg ctgctgccgg gtatgtgcac
181 ggcggctggg ggagccctgc gaccaactcc acgtctgcga cgccagccag ggcctggtct
241 gccagcccgg ggcaggaccc ggtggccggg gggccctgtg cctcttggca gaggacgaca
301 gcagctgtga ggtgaacggc cgcctgtatc gggaagggga gaccttccag ccccactgca
361 gcatccgctg ccgctgcgag gacggcggct tcacctgcgt gccgctgtgc agcgaggatg
421 tgcggctgcc cagctgggac tgcccccacc ccaggagggt cgaggtcctg ggcaagtgct
481 gccctgagtg ggtgtgcggc caaggagggg gactggggac ccagcccctt ccagcccaag
541 gaccccagtt ttctggcctt gtctcttccc tgccccctgg tgtcccctgc ccagaatgga
601 gcacggcctg gggaccctgc tcgaccacct gtgggctggg catggccacc cgggtgtcca
661 accagaaccg cttctgccga ctggagaccc agcgccgcct gtgcctgtcc aggccctgcc
721 caccctccag gggtcgcagt ccacaaaaca gtgccttcta gagccgggct gggaatgggg
781 acacggtgtc caccatcccc agctggtggc cctgtgcctg ggccctgggc tgatggaaga
841 tggtccgtgc ccaggccctt ggctgcaggc aacactttag cttgggtcca ccatgcagaa
901 caccaatatt aacacgctgc ctggtctgtc tggatcccga ggtatggcag aggtgcaaga
961 cctagtcccc tttcctctaa ctcactgcct aggaggctgg ccaaggtgtc cagggtcctc
1021 tagcccactc cctgcctaca cacacagcct atatcaaaca tgcacacggg cgagctttct
1081 ctccgacttc ccctgggcaa gagatgggac aagcagtccc ttaatattga ggctgcagca
1141 ggtgctgggc tggactggcc atttttctgg gggtaggatg aagagaaggc acacagagat
1201 tctggatctc ctgctgcctt ttctggagtt tgtaaaattg ttcctgaata caagcctatg
1261 cgtgaaaaaa aaaaaaaaaa aaa
//