LOCUS AF082556 4134 bp mRNA linear HUM 30-NOV-1998
DEFINITION Homo sapiens TRF1-interacting ankyrin-related ADP-ribose polymerase
mRNA, complete cds.
ACCESSION AF082556
VERSION AF082556.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4134)
AUTHORS Smith,S., Giriat,I., Schmitt,A. and de Lange,T.
TITLE Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
JOURNAL Science 282 (5393), 1484-1487 (1998)
PUBMED 9822378
REFERENCE 2 (bases 1 to 4134)
AUTHORS Smith,S., Giriat,I., Schmitt,A. and de Lange,T.
TITLE Direct Submission
JOURNAL Submitted (06-AUG-1998) Laboratory for Cell Biology and Genetics,
The Rockefeller University, 1230 York Avenue, New York, NY 10021,
USA
FEATURES Location/Qualifiers
source 1..4134
/db_xref="H-InvDB:HIT000066520"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="testis"
CDS 6..3989
/note="tankyrase"
/codon_start=1
/product="TRF1-interacting ankyrin-related ADP-ribose
polymerase"
/protein_id="AAC79841.1"
/translation="MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTT
PASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCCSTTSTICTVAAA
PVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAESPEAAGVS
STAPLGPGAAGPGTGVPAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSS
PLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPN
ARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY
KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHG
ADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEV
CSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKT
LALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAA
ERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQG
FTAAQMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEG
RHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHG
ASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQ
DLLKGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYL
LEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKG
RTQLCALLLAHGADPTMKNQEGQTPLDLATADDIRALLIDAMPPEALPTCFKPQATVV
SASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAGDGAAGTERKEGEVAGLDMN
ISQFLKSLGLEHLRDIFETEQITLDVLADMGHEELKEIGINAYGHRHKLIKGVERLLG
GQQGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYN
VIRIQKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYI
GGMFGAGIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQ
FSTMKMAHAPPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTA
TAAEQKT"
BASE COUNT 1112 a 1041 c 1034 g 947 t
ORIGIN
1 cgaagatggc ggcgtcgcgt cgctctcagc atcatcacca ccatcatcaa caacagctcc
61 agcccgcccc aggggcttca gcgccgccgc cgccacctcc tcccccactc agccctggcc
121 tggccccggg gaccacccca gcctctccca cggccagcgg cctggccccc ttcgcctccc
181 cgcggcacgg cctagcgctg ccggaggggg atggcagtcg ggatccgccc gacaggcccc
241 gatccccgga cccggttgac ggtaccagct gttgcagtac caccagcaca atctgtaccg
301 tcgccgccgc tcccgtggtc ccagcggttt ctacttcatc tgccgctggg gtcgctccca
361 acccagccgg cagtggcagt aacaattcac cgtcgtcctc ttcttccccg acttcttcct
421 catcttcctc tccatcctcc cctggatcga gcttggcgga gagccccgag gcggccggag
481 ttagcagcac agcaccactg gggcctgggg cagcaggacc tgggacaggg gtcccagcag
541 tgagcggggc cctacgggaa ctgctggagg cctgtcgcaa tggggacgtg tcccgggtaa
601 agaggctggt ggacgcggca aacgtaaatg caaaggacat ggccggccgg aagtcttctc
661 ccctgcactt cgctgcaggt tttggaagga aggatgttgt agaacactta ctacagatgg
721 gtgctaatgt ccacgctcgt gatgatggag gtctcatccc gcttcataat gcctgttctt
781 ttggccatgc tgaggttgtg agtctgttat tgtgccaagg agctgatcca aatgccaggg
841 ataactggaa ctatacacct ctgcatgaag ctgctattaa agggaagatc gatgtgtgca
901 ttgtgctgct gcagcacgga gctgacccaa acattcggaa cactgatggg aaatcagccc
961 tggacctggc agatccttca gcaaaagctg tccttacagg tgaatacaag aaagacgaac
1021 tcctagaagc tgctaggagt ggtaatgaag aaaaactaat ggctttactg actcctctaa
1081 atgtgaattg ccatgcaagt gatgggcgaa agtcgactcc tttacatcta gcagcgggct
1141 acaacagagt tcgaatagtt cagcttcttc ttcagcatgg tgctgatgtt catgcaaaag
1201 acaaaggtgg acttgtgcct cttcataatg catgttcata tggacattat gaagtcacag
1261 aactgctact aaagcatgga gcttgtgtta atgccatgga tctctggcag tttactccac
1321 tgcacgaggc tgcttccaag aaccgtgtag aagtctgctc tttgttactt agccatggcg
1381 ctgatcctac gttagtcaac tgccatggca aaagtgctgt ggatatggct ccaactccgg
1441 agcttaggga gagattgact tatgaattta aaggtcattc tttactacaa gcagccagag
1501 aagcagactt agctaaagtt aaaaaaacac tcgctctgga aatcattaat ttcaaacaac
1561 cgcagtctca tgaaacagca ctgcactgtg ctgtggcctc tctgcatccc aaacgtaaac
1621 aagtgacaga attgttactt agaaaaggag caaatgttaa tgaaaaaaat aaagatttca
1681 tgactcccct gcatgttgca gccgaaagag cccataatga tgtcatggaa gttctgcata
1741 agcatggcgc caagatgaat gcactggaca cccttggtca gactgctttg catagagccg
1801 ccctagcagg ccacctgcag acctgccgcc tcctgctgag ttacggctct gacccctcca
1861 tcatctcctt acaaggcttc acagcagcac agatgggcaa tgaagcagtg cagcagattc
1921 tgagtgagag tacacctata cgtacttctg atgttgatta tcgactctta gaggcatcta
1981 aagctggaga cttggaaact gtgaagcaac tttgcagctc tcaaaatgtg aattgtagag
2041 acttagaggg ccggcattcc acgcccttac acttcgcagc aggctacaac cgcgtgtctg
2101 ttgtagagta cctgctacac cacggtgccg atgtccatgc caaagacaag ggtggcttgg
2161 tgccccttca taatgcctgt tcatatggac actatgaggt ggctgagctt ttagtaaggc
2221 atggggcttc tgtcaatgtg gcggacttat ggaaatttac ccctctccat gaagcagcag
2281 ctaaaggaaa gtatgaaatc tgcaagctcc ttttaaaaca tggagcagat ccaactaaaa
2341 agaacagaga tggaaataca cctttggatt tggtaaagga aggagacaca gatattcagg
2401 acttactgaa aggggatgct gctttgttgg atgctgccaa gaagggctgc ctggcaagag
2461 tgcagaagct ctgtacccca gagaatatca actgcagaga cacccagggc agaaattcaa
2521 cccctctgca cctggcagca ggctataata acctggaagt agctgaatat cttctagagc
2581 atggagctga tgttaatgcc caggacaagg gtggtttaat tcctcttcat aatgcggcat
2641 cttatgggca tgttgacata gcggctttat tgataaaata caacacgtgt gtaaatgcaa
2701 cagataagtg ggcgtttact cccctccatg aagcagccca gaaaggaagg acgcagctgt
2761 gcgccctcct cctagcgcat ggtgcagacc ccaccatgaa gaaccaggaa ggccagacgc
2821 ctctggatct ggcaacagct gacgatatca gagctttgct gatagatgcc atgcccccag
2881 aggccttacc tacctgtttt aaacctcagg ctactgtagt gagtgcctct ctgatctcac
2941 cagcatccac cccctcctgc ctctcggctg ccagcagcat agacaacctc actggccctt
3001 tagcagagtt ggccgtagga ggagcctcca atgcagggga tggcgccgcg ggaacagaaa
3061 ggaaggaagg agaagttgct ggtcttgaca tgaatatcag ccaatttcta aaaagccttg
3121 gccttgaaca ccttcgggat atctttgaaa cagaacagat tacactagat gtgttggctg
3181 atatgggtca tgaagagttg aaagaaatag gcatcaatgc atatgggcac cgccacaaat
3241 taatcaaagg agtagaaaga ctcttaggtg gacaacaagg caccaatcct tatttgactt
3301 ttcactgtgt taatcaggga acgattttgc tggatcttgc tccagaagat aaagaatatc
3361 agtcagtgga agaagagatg caaagtacta ttcgagaaca cagagatggt ggtaatgctg
3421 gcggcatctt caacagatac aatgtcattc gaattcaaaa agttgtcaac aagaagttga
3481 gggagcggtt ctgccaccga cagaaggaag tgtctgagga gaatcacaac catcacaatg
3541 agcgcatgtt gtttcatggt tctcctttca ttaatgccat tattcataaa gggtttgatg
3601 agcgacatgc atacatagga ggaatgtttg gggccgggat ttattttgct gaaaactcct
3661 caaaaagcaa ccaatatgtt tatggaattg gaggaggaac aggctgccct acacacaagg
3721 acaggtcatg ctatatatgt cacagacaaa tgctcttctg tagagtgacc cttgggaaat
3781 cctttctgca gtttagcacc atgaaaatgg cccacgcgcc tccagggcac cactcagtca
3841 ttggtagacc gagcgtcaat gggctggcat atgctgaata tgtcatctac agaggagaac
3901 aggcataccc agagtatctt atcacttacc agatcatgaa gccagaagcc ccttcccaga
3961 ccgcaacagc cgcagagcag aagacctagt gaatgcctgc tggtgaaggc cagatcagat
4021 ttcaacctgg gactggatta cagaggattg tttctaataa caacatcaat attctagaag
4081 tccctgacag cctagaaata agctgtttgt cttctataaa gcattgctat agtg
//