LOCUS AF081571 3016 bp mRNA linear HUM 08-JUN-1999
DEFINITION Homo sapiens sodium-dependent multi-vitamin transporter (SMVT)
mRNA, complete cds.
ACCESSION AF081571
VERSION AF081571.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3016)
AUTHORS Prasad,P.D., Wang,H., Huang,W., Fei,Y.J., Leibach,F.H., Devoe,L.D.
and Ganapathy,V.
TITLE Molecular and functional characterization of the intestinal
Na+-dependent multivitamin transporter
JOURNAL Arch. Biochem. Biophys. 366 (1), 95-106 (1999)
PUBMED 10334869
REFERENCE 2 (bases 1 to 3016)
AUTHORS Prasad,P.D., Wang,H., Leibach,F.H. and Ganapathy,V.
TITLE Direct Submission
JOURNAL Submitted (31-JUL-1998) Obstetrics & Gynecology, Medical College of
Georgia, 1120 15th Street, Augusta, GA 30912, USA
FEATURES Location/Qualifiers
source 1..3016
/db_xref="H-InvDB:HIT000066485"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p23"
/cell_line="Caco-2"
/tissue_type="intestine"
gene 1..3016
/gene="SMVT"
CDS 208..2115
/gene="SMVT"
/function="transports pantothenate, biotin and lipoate in
the presence of sodium"
/note="membrane bound transport protein"
/codon_start=1
/product="sodium-dependent multi-vitamin transporter"
/protein_id="AAD37481.1"
/translation="MSVGVSTSAPLSPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGL
YHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGVPSEIYRFGTQYWFL
GCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKTVRVCGTVTFIFQMVIYMGVV
LYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVI
IVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQA
QVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPD
QFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSE
ARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPC
ANPPGAVVGLLAGLVMAFWIGIGSIVTSMGFSMPPSPSNGSSFSLPTNLTVATVTTLM
PLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVL
PKLLSLLPLSCQKRLHCRSYGQDHLDTGLFPEKPRNGVLGDSRDKEAMALDGTAYQGS
SSTCILQETSL"
BASE COUNT 609 a 839 c 784 g 784 t
ORIGIN
1 gaaaagggag cgatgttgat ctcaggaagc acaaagggac cttcctagct ctgactgaac
61 cacggagctc accctggaca gtatcactcc gtggaggaag actgtgagac tgtggctgga
121 agccagattg tagccacaca tccgcccctg ccctacccca gagccctgga gcagcaactg
181 gctgcagatc acagacacag tgaggatatg agtgtagggg tgagcacctc agcccctctt
241 tccccaacct cgggcacaag cgtgggcatg tctaccttct ccatcatgga ctatgtggtg
301 ttcgtcctgc tgctggttct ctctcttgcc attgggctct accatgcttg tcgtggctgg
361 ggccggcata ctgttggtga gctgctgatg gcggaccgca aaatgggctg ccttccggtg
421 gcactgtccc tgctggccac cttccagtca gccgtggcca tcctgggtgt gccgtcagag
481 atctaccgat ttgggaccca atattggttc ctgggctgct gctactttct ggggctgctg
541 atacctgcac acatcttcat ccccgttttc taccgcctgc atctcaccag tgcctatgag
601 tacctggagc ttcgattcaa taaaactgtg cgagtgtgtg gaactgtgac cttcatcttt
661 cagatggtga tctacatggg agttgtgctc tatgctccgt cattggctct caatgcagtg
721 actggctttg atctgtggct gtccgtgctg gccctgggca ttgtctgtac cgtctataca
781 gctctgggtg ggctgaaggc cgtcatctgg acagatgtgt tccagacact ggtcatgttc
841 ctcgggcagc tggcagttat catcgtgggg tcagccaagg tgggcggctt ggggcgtgtg
901 tgggccgtgg cttcccagca cggccgcatc tctgggtttg agctggatcc agaccccttt
961 gtgcggcaca ccttctggac cttggccttc gggggtgtct tcatgatgct ctccttatac
1021 ggggtgaacc aggctcaggt gcagcggtac ctcagttccc gcacggagaa ggctgctgtg
1081 ctctcctgtt atgcagtgtt ccccttccag caggtgtccc tctgcgtggg ctgcctcatt
1141 ggcctggtca tgttcgcgta ttaccaggag tatcccatga gcattcagca ggctcaggca
1201 gccccagacc agttcgtcct gtactttgtg atggatctcc tgaagggcct gccaggcctg
1261 ccagggctct tcattgcctg cctcttcagc ggctctctca gcactatatc ctctgctttt
1321 aattcattgg caactgttac gatggaagac ctgattcgac cttggttccc tgagttctct
1381 gaagcccggg ccatcatgct ttccagaggc cttgcctttg gctatgggct gctttgtcta
1441 ggaatggcct atatttcctc ccagatggga cctgtgctgc aggcagcaat cagcatcttt
1501 ggcatggttg ggggaccgct gctgggactc ttctgccttg gaatgttctt tccatgtgct
1561 aaccctcctg gtgctgttgt gggcctgttg gctgggctcg tcatggcctt ctggattggc
1621 atcgggagca tcgtgaccag catgggcttc agcatgccac cctctccctc taatgggtcc
1681 agcttctccc tgcccaccaa tctaaccgtt gccactgtga ccacactgat gcccttgact
1741 accttctcca agcccacagg gctgcagcgg ttctattcct tgtcttactt atggtacagt
1801 gctcacaact ccaccacagt gattgtggtg ggcctgattg tcagtctact cactgggaga
1861 atgcgaggcc ggtccctgaa ccctgcaacc atttacccag tgttgccaaa gctcctgtcc
1921 ctccttccgt tgtcctgtca gaagcggctc cactgcagga gctacggcca ggaccacctc
1981 gacactggcc tgtttcctga gaagccgagg aatggtgtgc tgggggacag cagagacaag
2041 gaggccatgg ccctggatgg cacagcctat caggggagca gctccacctg catcctccag
2101 gagacctccc tgtgatgttg actcaggacc ccgcctctgt cctcactgtg ccaggccata
2161 gccagaggcc accctgtagt acagggatga gtcttggtgt gttctgcagg gacaggcctg
2221 gatgatctag ctcataccaa aggaccttgt tctgagaggt tcttgcctgc aggagaagct
2281 gtcacatctc aagcatgtga ggcaccgttt ttctcgtcgc ttgccaatct gttttttaaa
2341 ggatcaggct cgtagggagc aggatcatgc cagaaatagg gatggaagtg catcctctgg
2401 gaaaaagata atggcttctg attcaacata gccatagtcc tttgaagtaa gtggctagaa
2461 acagcactct ggttataatt gccccagggc ctgattcagg actgactctc caccataaaa
2521 ctggaagctg cttcccctgt agtccccatt tcagtaccag ttctgccagc cacagtgagc
2581 ccctattatt actttcagat tgtctgtgac actcaagccc ctctcatttt tatctgtcta
2641 cctccattct gaagagggag gttttggtgt ccctggtcct ctgggaatag aagatccatt
2701 tgtctttgtg tagagcaagc acgttttcca cctcactgtc tccatcctcc acctctgaga
2761 tggacactta agagacgggg caaatgtgga tccaagaaac cagggccatg accaggtcca
2821 ctgtggagca gccatctatc tacctgactc ctgagccagg ctgccgtggt gtcatttctg
2881 tcatccgtgc tctgtttcct tttggagttt cttctccaca ttatctttgt tcctggggaa
2941 taaaaactac cattggacct aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3001 aaaaaaaaaa aaaaaa
//