LOCUS AF081287 3291 bp mRNA linear HUM 19-OCT-1998
DEFINITION Homo sapiens serine phosphatase FCP1a (FCP1) mRNA, complete cds.
ACCESSION AF081287
VERSION AF081287.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3291)
AUTHORS Archambault,J., Pan,G., Dahmus,G.K., Cartier,M., Marshall,N.,
Zhang,S., Dahmus,M.E. and Greenblatt,J.
TITLE FCP1, the RAP74-interacting subunit of a human protein phosphatase
that dephosphorylates the carboxyl-terminal domain of RNA
polymerase IIO
JOURNAL J. Biol. Chem. 273 (42), 27593-27601 (1998)
PUBMED 9765293
REFERENCE 2 (bases 1 to 3291)
AUTHORS Archambault,J., Cartier,M. and Greenblatt,J.
TITLE Direct Submission
JOURNAL Submitted (29-JUL-1998) Banting and Best Department of Medical
Research, University of Toronto, 112 College Street, Toronto,
Ontario M5G 1L6, Canada
FEATURES Location/Qualifiers
source 1..3291
/db_xref="H-InvDB:HIT000066472"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="lymphocyte"
/tissue_type="placenta"
gene 1..3291
/gene="FCP1"
CDS 53..2581
/gene="FCP1"
/note="component of RNA polymerase II holoenzyme;
Mg-dependent; okadaic acid-resistant; activity stimulated
by TFIIF and inhibited by TFIIB; specific for the
C-terminal heptapeptide repeat domain of the RNA
polymerase II largest subunit"
/codon_start=1
/product="serine phosphatase FCP1a"
/protein_id="AAC64549.1"
/translation="MKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVHSVAELMVSS
EQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPML
HTRLRPHCKDFLEKIAKLYELHVFTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECID
PFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPGSRE
SQTRKKVNHSRGTEVSEPSPPVRDPEGVTQAPGVEPSNGLEKPARELNGSEAPTPRDS
PRPGKPDERDIWPPAQAPTSSQELAGAPEPQGSCAQGGRVAPGQRPAQGATGTDLDFD
LSSDSESSSESEGTKSSSSASDGETEGKRGRQNAKAAPEGAGALAQGSSLDAGRPAAP
SVPGEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAG
ESLDQSMEEEEEEDTDEDDHLIYLEEILVRVHTDYYAKYDRYLNKEIEEAPDIRKIVP
ELKSKVLADVAIIFSGLHPTNFPIEKTRDDYHATALGAKILTRLVLSPDAPDRATHLI
AARAGTEKVLQAQECGHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAA
FPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRTGARGPPAPSSSLPIRQE
PSSFRAVPPPQPQMFGEELPDAQDGEQPGPSRRKRQPSMSETMPLYTLCKEDLESMDK
EVDDILGEGSDDSDSEKRRPEEQEEEPQPRKPGTRRERTLGAPASSERSAAGGRGPRG
HKRKLNEEDAASESSRESSNEDEGSSSEADEMAKALEAELNDLM"
BASE COUNT 737 a 957 c 1042 g 555 t
ORIGIN
1 cctagacaga gtggttctgg tgaggttgga aggatgcagc cacccggttg tcatgaaagg
61 cctgtgtgct gaatgtggcc aagacctcac ccagttgcag agtaagaacg ggaagcagca
121 ggtgccgctg tccacggcga ccgtgtccat ggtgcacagc gtcgcggagt tgatggtgag
181 ctccgagcaa gctgaacagc tgggaagaga agaccagcag cgactgcacc gaaaccggaa
241 gctggtgctc atggtggact tggaccagac gttgattcac acaaccgagc agcactgtca
301 gcagatgtcg aataaaggca tctttcactt ccagctgggc cggggtgagc ccatgctgca
361 cacgcgcctg cgtccacact gcaaggactt cctggagaag atcgccaagc tgtacgagct
421 gcacgtcttc accttcggca gccggctgta cgcacacacc atcgcaggct ttttagaccc
481 cgagaagaag cttttttctc accgaatatt atcaagggat gaatgtattg acccattttc
541 taaaacggga aaccttagaa atctctttcc ttgtggagac tcaatggttt gcattattga
601 tgatcgagaa gatgtctgga agtttgcccc caatctgata actgtgaaga aatatgtata
661 cttccagggc acaggtgata tgaatgcgcc ccctgggtcc cgagaatctc agacgagaaa
721 gaaagtaaat cattctcgag gcactgaggt ctcagagcca tctccgcccg tgagagaccc
781 tgagggggta acgcaggccc ctggagtgga gcccagcaat ggcctggaga agcctgcacg
841 ggagctgaac ggcagcgagg cgcccacccc gcgggactca ccccgccccg ggaagccaga
901 cgagagggac atctggcccc ctgcccaggc ccccaccagc agccaagagc tggcaggcgc
961 tcctgagccc cagggatcct gtgcgcaggg tggccgggtg gcaccgggac agcggcctgc
1021 ccagggtgcc acgggcactg acctggactt tgacttatcc agcgacagcg agagcagcag
1081 tgagtccgag ggcacgaagt cctcctcctc cgcctctgat ggcgaaacgg aggggaaaag
1141 aggccggcag aacgcgaagg ctgccccaga gggagccggg gcgctggcac agggcagttc
1201 cctggacgcg gggcggcctg cagcaccgag tgtccccgga gaggccgagc ctggcgcgca
1261 tgccccggac aaggagcctg agctgggtgg gcaggaggag ggcgagcggg atggcctctg
1321 cggcctgggc aacggctgtg ccgacaggaa ggaggcggag accgagtcac agaacagcga
1381 gctgtcgggg gtcactgcgg gtgagtccct ggaccagagc atggaggagg aggaggagga
1441 ggacacggat gaggatgacc acctcatcta cctggaggag atcctggtcc gtgtacacac
1501 tgactactat gccaagtatg accgctacct caacaaggag atcgaggagg cgccggacat
1561 ccgcaagatc gtgccggagc tcaagagcaa ggtgctggca gacgtggcca taattttcag
1621 tgggctacac ccgacaaact tcccgataga gaagacgcgg gacgattacc acgccacggc
1681 gctgggagcg aagatcctca ctcggctggt gctgagcccc gacgcccctg acagggccac
1741 gcacctgatc gccgcgcgag ctggcacaga gaaggtgctg caggcacagg agtgcggaca
1801 cctgcacgtg gtcaaccctg actggctgtg gagctgcctg gagcgctggg acaaggtgga
1861 ggagcagctc ttcccgctca gggacgatca caccaaggca cagagggaga acagccctgc
1921 ggcctttccc gaccgggagg gtgtgccccc caccgccttg ttccacccga tgccggttct
1981 tcccaaggcc cagcctggcc ccgaggttcg gatctacgac tccaacacgg ggaagctcat
2041 caggaccggc gcccgggggc ccccagcacc ctccagctcc ctacccatcc gccaggagcc
2101 ctcttccttc agagcggttc cgccacccca gccgcagatg tttggtgaag agctgcctga
2161 cgctcaggac ggagagcagc ctggcccttc tagaagaaag cgacagccca gtatgtctga
2221 gacaatgccg ctgtacactc tttgtaagga ggatttagag agtatggaca aagaggtgga
2281 cgacatcctt ggagaaggca gcgacgacag cgacagcgag aagaggaggc ctgaggagca
2341 ggaggaggag ccccagcccc ggaagccagg gacccgcagg gagcggacgc tcggggcacc
2401 tgcgtccagc gagaggagcg cggcaggggg ccgggggccc agaggccaca agaggaagct
2461 gaatgaagag gacgccgcca gcgagtccag cagggagtcc agcaacgagg acgagggcag
2521 cagctccgag gccgacgaga tggccaaggc gctggaggcg gagctcaacg acctcatgtg
2581 agcgcgggca gcgggcaggg actgaagcct gaccgacctc cagcagcact cggacgtccc
2641 cggaccagcc ctcagtctcg gtccacgctg ctttcttccc aaaggacatg tatatttgca
2701 gagctccaca tacagaaaca cattattttg cagaaatagg tgtttttaag aagttttact
2761 acaggaatgt ctacttttgt aagtgacagg tgttaaaggc ccaggtgtgc tgtgccaaag
2821 agctcagcag aggctcacgt ggcccaggct ggtgcgcccg ctgtctcggt aaggggcggg
2881 ttggtgtgtt ttccccttgt gtaccagagc acattcctta ggggacggct ttccccctcc
2941 cacgagacat ggactaggag tttaagcagg acagtgtgcg tgcacgagct ccgagcccag
3001 cacagacatg cctggaaccc ccgccgcctg ctgctccctc ctagggaacc catttccggg
3061 gaacgccgtg actgtcgggc agcctggagc ttcctgcagc ctcctacgca gggtcacgcc
3121 acgtggcctg ggctgccatc ctgccgtcct cccactggca tcctggcaag ggggcgttgc
3181 ttttcctggg cggcctttta tgtcttggag acacctgatg taaagtttct gtaaatctat
3241 ttcatatctg acccaccaaa cagatttctc tttaataaaa atcctttttg t
//