LOCUS AF080227 1879 bp mRNA linear HUM 12-DEC-1998
DEFINITION Homo sapiens embryonic ectoderm development protein mRNA, complete
cds.
ACCESSION AF080227
VERSION AF080227.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1879)
AUTHORS Schumacher,A., Lichtarge,O., Schwartz,S. and Magnuson,T.
TITLE The murine Polycomb-group gene eed and its human orthologue:
functional implications of evolutionary conservation
JOURNAL Genomics 54 (1), 79-88 (1998)
PUBMED 9806832
REFERENCE 2 (bases 1 to 1879)
AUTHORS Schumacher,A., Lichtarge,O., Schwartz,S. and Magnuson,T.
TITLE Direct Submission
JOURNAL Submitted (26-JUL-1998) Molecular and Human Genetics, Baylor
College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
FEATURES Location/Qualifiers
source 1..1879
/db_xref="H-InvDB:HIT000066439"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q14.2-q22.3; putatively 11q14.3"
/tissue_type="brain"
/dev_stage="adult"
CDS 345..1670
/function="putative transcriptional repressor of homeotic
genes"
/note="polycomb-group protein; homolog of Drosophila esc
(extra sex combs); EED"
/codon_start=1
/product="embryonic ectoderm development protein"
/protein_id="AAC95144.1"
/translation="MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSI
ESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFN
WHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSH
PLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLW
NIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKE
SYDYNPNKTNRPFISQKIHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPG
KMEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLE
VEDPHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR"
misc_feature 615..719
/note="encodes WD motif I"
misc_feature 906..1001
/note="encodes WD motif II"
misc_feature 1044..1136
/note="encodes WD motif III"
misc_feature 1254..1340
/note="encodes WD motif IV"
misc_feature 1566..1658
/note="encodes WD motif V"
BASE COUNT 541 a 344 c 499 g 495 t
ORIGIN
1 gggggaaggg agacatactt aatactgccc tcttaatcca acggacctta catcgtgtag
61 actgccggga gggcggcggg aaaagggcaa gacgggagtt ggggaaggga aggagccagg
121 aagccgcgcg ggagggcgcg cgcgcgcgcc cctttttcag cagtgtggcg gggtcgcacg
181 cacgcccgcc tcggcggctg ggcgcgattt gcgacagtgg ggggggcggt ggaggtggcg
241 gcggcagcgg caactttgcg gcaagctcgg gccgggcttg cttgacggcg gtgtggcgga
301 ggccccgccc caggcggcag gaacctggag ggaggcggag gaatatgtcc gagagggaag
361 tgtcgactgc gccggcggga acagacatgc ctgcggccaa gaagcagaag ctgagcagtg
421 acgagaacag caatccagac ctctctggag acgagaatga tgacgctgtc agtatagaaa
481 gtggtacaaa cactgaacgc cctgatacac ctacaaacac gccaaatgca cctggaagga
541 aaagttgggg aaagggaaaa tggaagtcaa agaaatgcaa atattctttc aaatgtgtaa
601 atagtctcaa ggaagatcat aaccaaccat tgtttggagt tcagtttaac tggcacagta
661 aagaaggaga tccattagtg tttgcaactg taggaagcaa cagagttacc ttgtatgaat
721 gtcattcaca aggagaaatc cggttgttgc aatcttacgt ggatgctgat gctgatgaaa
781 acttttacac ttgtgcatgg acctatgata gcaatacgag ccatcctctg ctggctgtag
841 ctggatctag aggcataatt aggataataa atcctataac aatgcagtgt ataaagcact
901 atgttggcca tggaaatgct atcaatgagc tgaaattcca tccaagagat ccaaatcttc
961 tcctgtcagt aagtaaagat catgctttac gattatggaa tatccagacg gacactctgg
1021 tggcaatatt tggaggcgta gaagggcaca gagatgaagt tctaagtgct gattatgatc
1081 ttttgggtga aaaaataatg tcctgtggta tggatcattc tcttaaactt tggaggatca
1141 attcaaagag aatgatgaat gcaattaagg aatcttatga ttataatcca aataaaacta
1201 acaggccatt tatttctcag aaaatccatt ttcctgattt ttctaccaga gacatacata
1261 ggaattatgt tgattgtgtg cgatggttag gcgatttgat actttctaag tcttgtgaaa
1321 atgccattgt gtgctggaaa cctggcaaga tggaagatga tatagataaa attaaaccca
1381 gtgaatctaa tgtgactatt cttgggcgat ttgattacag ccagtgtgac atttggtaca
1441 tgaggttttc tatggatttc tggcaaaaga tgcttgcatt gggcaatcaa gttggcaaac
1501 tttatgtttg ggatttagaa gtagaagatc ctcataaagc caaatgtaca acactgactc
1561 atcataaatg tggtgctgct attcgacaaa ccagttttag cagggatagc agcattctta
1621 tagctgtttg tgatgatgcc agtatttggc gctgggatcg acttcgataa aatacttttg
1681 cctaatcaaa attagagtgt gtttgttgtc tgtgtaaaat agaattaatg tatcttgcta
1741 gtaagggcac gtagagcatt tagagttgtc tttcagcatt caatcaggct gagctgaatg
1801 tagtgatgtt tacattgttt acattctttg tactgtcttc ctgctcagac tctactgctt
1861 ttaataaaaa tttattttt
//