LOCUS AF080214 1534 bp mRNA linear HUM 26-SEP-2002
DEFINITION Homo sapiens protease-activated receptor 4 mRNA, complete cds.
ACCESSION AF080214
VERSION AF080214.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1534)
AUTHORS Kahn,M.L., Zheng,Y.W., Huang,W., Bigornia,V., Zeng,D., Moff,S.,
Farese,R.V. Jr., Tam,C. and Coughlin,S.R.
TITLE A dual thrombin receptor system for platelet activation
JOURNAL Nature 394 (6694), 690-694 (1998)
PUBMED 9716134
REFERENCE 2 (bases 1 to 1534)
AUTHORS Kahn,M.L., Hammes,S.R., Botka,C. and Coughlin,S.R.
TITLE Gene and locus structure and chromosomal localization of the
protease-activated receptor gene family
JOURNAL J. Biol. Chem. 273 (36), 23290-23296 (1998)
PUBMED 9722561
REFERENCE 3 (bases 1 to 1534)
AUTHORS Kahn,M.L. and Coughlin,S.R.
TITLE Direct Submission
JOURNAL Submitted (24-JUL-1998) CVRI, UCSF, 513 Parnassus, San Francisco,
CA 94143-1030, USA
FEATURES Location/Qualifiers
source 1..1534
/db_xref="H-InvDB:HIT000066437"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p12"
CDS 3..1160
/note="G protein-coupled receptor; thrombin receptor;
PAR4"
/codon_start=1
/product="protease-activated receptor 4"
/protein_id="AAC28860.1"
/translation="MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILP
APRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVL
ATQAPRLPSTMLLMNLATADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHM
YGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTF
RLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGR
RYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSC
VDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ"
BASE COUNT 235 a 526 c 479 g 293 t
ORIGIN
1 tcatgtgggg gcgactgctc ctgtggcccc tggtgctggg gttcagcctg tctggcggca
61 cccagacccc cagcgtctac gacgagagcg ggagcaccgg aggtggtgat gacagcacgc
121 cctcaatcct gcctgccccc cgcggctacc caggccaagt ctgtgccaat gacagtgaca
181 ccctggagct cccggacagc tcacgggcac tgcttctggg ctgggtgccc accaggctgg
241 tgcccgccct ctatgggctg gtcctggtgg tggggctgcc ggccaatggg ctggcgctgt
301 gggtgctggc cacgcaggca cctcggctgc cctccaccat gctgctgatg aacctcgcga
361 ctgctgacct cctgctggcc ctggcgctgc ccccgcggat cgcctaccac ctgcgtggcc
421 agcgctggcc cttcggggag gccgcctgcc gcctggccac ggccgcactc tatggtcaca
481 tgtatggctc agtgctgctg ctggccgccg tcagcctgga tcgctacctg gccctggtgc
541 acccgctgcg ggcccgcgcc ctgcgtggcc ggcgcctggc ccttggactc tgcatggctg
601 cttggctcat ggcggccgcc ctggcactgc ccctgacact gcagcggcag accttccggc
661 tggcgcgctc cgatcgcgtg ctctgccatg acgcgctgcc cctggacgca caggcctccc
721 actggcaacc ggccttcacc tgcctggcgc tgttgggctg tttcctgccc ctgctggcca
781 tgctgctgtg ctacggggcc accctgcaca cgctggcggc cagcggccgg cgctacggcc
841 acgcgctgag gctgaccgca gtggtgctgg cctccgccgt ggccttcttc gtgcccagca
901 acctgctgct gctgctgcat tactcggacc cgagccccag cgcctggggc aacctctatg
961 gtgcctacgt gcccagcctg gcgctgagca ccctcaacag ctgcgtggat cccttcatct
1021 actactacgt gtcggccgag ttcagggaca aggtgcgggc agggctcttc caacggtcgc
1081 cgggggacac cgtggcctcc aaggcctctg cggaaggggg cagccggggc atgggcaccc
1141 actcctcttt gctccagtga cacaaagtgg ggaaggctgt actgggtcga acagggtccc
1201 ttcccccact tcacgtcctt cctgggacct cagaatgtga ccttatttgg aaatagggtt
1261 gttacaactg tcactagcag aggtcacttt ggagaagggt gggccttaca tccagtgtgg
1321 gtggtgtcct cataagataa ggagaggcca ggcctggtgg ctcacgcctg taatcccagc
1381 actttaagag gccaaggcgg atggatcact tgagcccagg agttcaacac cagcctgagc
1441 aacatggtaa aaccccatct ctaccaaaaa tacaaaaatt agctgggctt ggtggctggc
1501 gcctgtaatc ccagctactc angagactga ggca
//