LOCUS AF077951 1953 bp mRNA linear HUM 23-SEP-1998
DEFINITION Homo sapiens protein inhibitor of activated STAT protein PIAS1
mRNA, complete cds.
ACCESSION AF077951
VERSION AF077951.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1953)
AUTHORS Liu,B., Liao,J., Rao,X., Kushner,S.A., Chung,C.D., Chang,D.D. and
Shuai,K.
TITLE Inhibition of Stat1-mediated gene activation by PIAS1
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (18), 10626-10631 (1998)
PUBMED 9724754
REFERENCE 2 (bases 1 to 1953)
AUTHORS Liu,B., Liao,J., Rao,X., Kushner,S.A., Chung,C.D., Chang,D.D. and
Shuai,K.
TITLE Direct Submission
JOURNAL Submitted (15-JUL-1998) Hematology-Oncology, UCLA, 10833 Le Conte
Avenue, Los Angeles, CA 90095, USA
FEATURES Location/Qualifiers
source 1..1953
/db_xref="H-InvDB:HIT000066233"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..1953
/codon_start=1
/product="protein inhibitor of activated STAT protein
PIAS1"
/protein_id="AAC36702.1"
/translation="MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHL
LKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGH
PASSPLLPVSLLGPKHKLELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDN
SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPN
LCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTMCSWTAEIGRN
YSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLC
PLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFM
EILKYCTDCDEIQFKEDGTWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSS
NKNKKVEVIDLTIDSSSDEEEEEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRTP
SLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAA
VSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRESH
SHTVTNRSSTDTASIFGIIPDIISLD"
BASE COUNT 586 a 502 c 371 g 494 t
ORIGIN
1 atggcggaca gtgcggaact aaagcaaatg gttatgagcc ttagagtttc tgaactccaa
61 gtactgttgg gctacgccgg gagaaacaag cacggacgca aacacgaact tctcacaaaa
121 gccctgcatt tgctaaaggc tggctgtagt cctgctgtgc aaatgaaaat taaggaactc
181 tataggcggc ggttcccaca gaaaatcatg acgcctgcag acttgtccat ccccaacgta
241 cattcaagtc ctatgccagc aactttgtct ccatctacca ttccacaact cacttacgat
301 ggtcaccctg catcatcgcc attactccct gtttctcttc tgggacctaa acataaactg
361 gaactcccac atcttacatc agctcttcac ccagtccatc cggatataaa acttcaaaaa
421 ttaccatttt atgatttact ggatgaactg ataaaaccca ccagtctagc atcagacaac
481 agtcagcgct ttcgagaaac ctgttttgca tttgccttga caccacaaca agtgcagcaa
541 atcagtagtt ccatggatat ttctgggacc aaatgtgact tcacagtaca ggtccagtta
601 aggttttgtt tatcagaaac cagttgtcca caagaagatc acttcccacc caatctttgt
661 gtgaaagtga atacaaaacc ttgcagcctt ccaggttacc ttccacctac aaaaaatggc
721 gtggaaccaa agcgacccag ccgaccaatt aatatcacct cacttgtccg actgtccaca
781 acagtaccaa acacgatgtg ttcttggact gcagaaattg gaagaaacta ttccatggca
841 gtatatcttg taaaacagtt gtcctcaaca gttcttcttc agaggttacg agcaaaggga
901 ataaggaatc cggatcattc tagagcttta attaaagaga agttgactgc ggatccagac
961 agtgaaatag ctacaaccag cctaagggtt tctctactat gtccacttgg taaaatgcgg
1021 ctgacaattc cgtgtcgggc ccttacatgt tctcatctac aatgttttga cgcaactctt
1081 tacattcaga tgaatgagaa aaaaccaacc tgggtttgtc ctgtctgtga taagaaggct
1141 ccatatgaac accttattat tgatggcttg tttatggaaa tcctaaagta ctgtacagac
1201 tgtgatgaaa tacaatttaa ggaggatggc acttgggcac cgatgagatc aaaaaaggaa
1261 gtacaggaag tttctgcctc ttacaatgga gtcgatggat gcttgagctc cacattggag
1321 catcaggtag cgtctcacca ccagtcctca aataaaaaca agaaagtaga agtgattgac
1381 ctaaccatag acagttcatc tgatgaagag gaagaagagc catctgccaa gaggacctgt
1441 ccttccctat ctcccacatc accactaaat aataaaggca ttttaagtct tccacatcaa
1501 gcatctccag tatcccgcac cccaagcctt cctgctgtag acacaagcta cattaatacc
1561 tccctcatcc aagactatag gcatcctttc cacatgacac ccatgcctta cgacttacaa
1621 ggattagatt tctttccttt cttatcagga gacaatcagc attacaacac ctccttgctt
1681 gccgctgcag cagcagcagt ttcagatgat caagacctcc tacactcgtc tcggtttttc
1741 ccgtatacct cctcacagat gtttcttgat cagttaagtg caggaggcag tacttctctg
1801 ccaaccacca atggaagcag tagtggcagt aacagcagcc tggtttcttc caacagccta
1861 agggaaagcc atagccacac cgtcacaaac aggagcagca cggacacggc atccatcttt
1921 ggcatcatac cagacattat ttcattggac tga
//