LOCUS AF077820 5135 bp mRNA linear HUM 11-NOV-1998
DEFINITION Homo sapiens LDL receptor member LR3 mRNA, complete cds.
ACCESSION AF077820
VERSION AF077820.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5135)
AUTHORS Dong,Y., Lathrop,W., Weaver,D., Qiu,Q., Cini,J., Bertolini,D. and
Chen,D.
TITLE Molecular cloning and characterization of LR3, a novel LDL receptor
family protein with mitogenic activity
JOURNAL Biochem. Biophys. Res. Commun. 251 (3), 784-790 (1998)
PUBMED 9790987
REFERENCE 2 (bases 1 to 5135)
AUTHORS Dong,Y., Lathrop,W., Weaver,D., Qiu,Q., Cini,J., Bertolini,D. and
Chen,D.
TITLE Direct Submission
JOURNAL Submitted (13-JUL-1998) Bayer Pharmaceuticals, 400 Morgan Lane,
West Haven, CT 06516, USA
FEATURES Location/Qualifiers
source 1..5135
/db_xref="H-InvDB:HIT000066230"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11q13.4"
/cell_type="osteoblast; osteosarcoma"
CDS 89..4936
/codon_start=1
/product="LDL receptor member LR3"
/protein_id="AAC72791.1"
/translation="MEAAPPGPPWPLLLLLLLLLALCGCPAPAAASPLLLFANRRDVR
LVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNV
VISGLVSPDGLACDWVGKKLYWTDSETNRIEVANLNGTSRKVLFWQDLDQPRAIALDP
AHGYMYWTDWGETPRIERAGMDGSTRKIIVDSDIYWPNGLTIDLEEQKLYWADAKLSF
IHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQTRSIHACNKRTGGKRKEILS
ALYSPMDIQVLSQERQPFFHTRCEEDNGGCSHLCLLSPSEPFYTCACPTGVQLQDNGR
TCKAGAEEVLLLARRTDLRRISLDTPDFTDIVLQVDDIRHAIAIDYDPLEGYVYWTDD
EVRAIRRAYLDGSGAQTLVNTEINDPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTSR
KILVSEDLDEPRAIALHPVMGLMYWTDWGENPKIECANLDGQERRVLVNASLGWPNGL
ALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQRR
SIERVHKVKASRDVIIDQLPDLMGLKAVNVAKVVGTNPCADRNGGCSHLCFFTPHATR
CGCPIGLELLSDMKTCIVPEAFLVFTSRAAIHRISLETNNNDVAIPLTGVKEASALDF
DVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWADTGTN
RIEVARLDGQFRQVLVWRDLDNPRSLALDPTKGYIYWTEWGGKPRIVRAFMDGTNCMT
LVDKVGRANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIADDLPHPFGLTQYSD
YIYWTDWNLHSIERADKTSGRNRTLIQGHLDFVMDILVFHSSRQDGLNDCMHNNGQCG
QLCLAIPGGHRCGCASHYTLDPSSRNCSPPTTFLLFSQKSAISRMIPDDQHSPDLILP
LHGLRNVKAIDYDPLDKFIYWVDGRQNIKRAKDDGTQPFVLTSLSQGQNPDRQPHDLS
IDIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDRDKPRAIVVNAERGYLYFTNMQD
RAAKIERAALDGTEREVLFTTGLIRPVALVVDNTLGKLFWVDADLKRIESCDLSGANR
LTLEDANIVQPLGLTILGKHLYWIDRQQQMIERVEKTTGDKRTRIQGRVAHLTGIHAV
EEVSLEEFSAHPCARDNGGCSHICIAKGDGTPRCSCPVHLVLLQNLLTCGEPPTCSPD
QFACATGEIDCIPGAWRCDGFPECDDQSDEEGCPVCSAAQFPCARGQCVDLRLRCDGE
ADCQDRSDEADCDAICLPNQFRCASGQCVLIKQQCDSFPDCIDGSDELMCEITKPPSD
DSPAHSSAIGPVIGIILSLFVMGGVYFVCQRVVCQRYAGANGPFPHEYVSGTPHVPLN
FIAPGGSQHGPFTGIACGKSMMSSVSLMGGRGGVPLYDRNHVTGASSSSSSSTKATLY
PPILNPPPSPATDPSLYNMDMFYSSNIPATARPYRPYIIRGMAPPTTPCSTDVCDSDY
SASRWKASKYYLDLNSDSDPYPPPPTPHSQYLSAEDSCPPSPATERSYFHLFPPPPSP
CTDSS"
BASE COUNT 1035 a 1665 c 1561 g 874 t
ORIGIN
1 gaattcggca cgaggcgcga ggagccgccg ccgccgcgcc atggagcccg agtgagcgcg
61 gcgcgggccc gtccggccgc cggacaacat ggaggcagcg ccgcccgggc cgccgtggcc
121 gctgctgctg ctgctgctgc tgctgctggc gctgtgcggc tgcccggccc ccgccgcggc
181 ctcgccgctc ctgctatttg ccaaccgccg ggacgtacgg ctggtggacg ccggcggagt
241 caagctggag tccaccatcg tggtcagcgg cctggaggat gcggccgcag tggacttcca
301 gttttccaag ggagccgtgt actggacaga cgtgagcgag gaggccatca agcagaccta
361 cctgaaccag acgggggccg ccgtgcagaa cgtggtcatc tccggcctgg tctctcccga
421 cggcctcgcc tgcgactggg tgggcaagaa gctgtactgg acggactcag agaccaaccg
481 catcgaggtg gccaacctca atggcacatc ccggaaggtg ctcttctggc aggaccttga
541 ccagccaagg gccatcgcct tggaccccgc tcacgggtac atgtactgga cagactgggg
601 tgagacgccc cggattgagc gggcagggat ggatggcagc acccggaaga tcattgtgga
661 ctcggacatt tactggccca atggactgac catcgacctg gaggagcaga agctctactg
721 ggctgacgcc aagctcagct tcatccaccg tgccaacctg gacggctcgt tccggcagaa
781 ggtggtggag ggcagcctga cgcacccctt cgccctgacg ctctccgggg acactctgta
841 ctggacagac tggcagaccc gctccatcca tgcctgcaac aagcgcactg gggggaagag
901 gaaggagatc ctgagtgccc tctactcacc catggacatc caggtgctga gccaggagcg
961 gcagcctttc ttccacactc gctgtgagga ggacaatggc ggctgctccc acctgtgcct
1021 gctgtcccca agcgagcctt tctacacatg cgcctgcccc acgggtgtgc agctgcagga
1081 caacggcagg acgtgtaagg caggagccga ggaggtgctg ctgctggccc ggcggacgga
1141 cctacggagg atctcgctgg acacgccgga cttcaccgac atcgtgctgc aggtggacga
1201 catccggcac gccattgcca tcgactacga cccgctagag ggctatgtct actggacaga
1261 tgacgaggtg cgggccatcc gcagggcgta cctggacggg tctggggcgc agacgctggt
1321 caacaccgag atcaacgacc ccgatggcat cgcggtcgac tgggtggccc gaaacctcta
1381 ctggaccgac acgggcacgg accgcatcga ggtgacgcgc ctcaacggca cctcccgcaa
1441 gatcctggtg tcggaggacc tggacgagcc ccgagccatc gcactgcacc ccgtgatggg
1501 cctcatgtac tggacagact ggggagagaa ccctaaaatc gagtgtgcca acttggatgg
1561 gcaggagcgg cgtgtgctgg tcaatgcctc cctcgggtgg cccaacggcc tggccctgga
1621 cctgcaggag gggaagctct actggggaga cgccaagaca gacaagatcg aggtgatcaa
1681 tgttgatggg acgaagaggc ggaccctcct ggaggacaag ctcccgcaca ttttcgggtt
1741 cacgctgctg ggggacttca tctactggac tgactggcag cgccgcagca tcgagcgggt
1801 gcacaaggtc aaggccagcc gggacgtcat cattgaccag ctgcccgacc tgatggggct
1861 caaagctgtg aatgtggcca aggtcgtcgg aaccaacccg tgtgcggaca ggaacggggg
1921 gtgcagccac ctgtgcttct tcacacccca cgcaacccgg tgtggctgcc ccatcggcct
1981 ggagctgctg agtgacatga agacctgcat cgtgcctgag gccttcttgg tcttcaccag
2041 cagagccgcc atccacagga tctccctcga gaccaataac aacgacgtgg ccatcccgct
2101 cacgggcgtc aaggaggcct cagccctgga ctttgatgtg tccaacaacc acatctactg
2161 gacagacgtc agcctgaaga ccatcagccg cgccttcatg aacgggagct cggtggagca
2221 cgtggtggag tttggccttg actaccccga gggcatggcc gttgactgga tgggcaagaa
2281 cctctactgg gccgacactg ggaccaacag aatcgaagtg gcgcggctgg acgggcagtt
2341 ccggcaagtc ctcgtgtgga gggacttgga caacccgagg tcgctggccc tggatcccac
2401 caagggctac atctactgga ccgagtgggg cggcaagccg aggatcgtgc gggccttcat
2461 ggacgggacc aactgcatga cgctggtgga caaggtgggc cgggccaacg acctcaccat
2521 tgactacgct gaccagcgcc tctactggac cgacctggac accaacatga tcgagtcgtc
2581 caacatgctg ggtcaggagc gggtcgtgat tgccgacgat ctcccgcacc cgttcggtct
2641 gacgcagtac agcgattata tctactggac agactggaat ctgcacagca ttgagcgggc
2701 cgacaagact agcggccgga accgcaccct catccagggc cacctggact tcgtgatgga
2761 catcctggtg ttccactcct cccgccagga tggcctcaat gactgtatgc acaacaacgg
2821 gcagtgtggg cagctgtgcc ttgccatccc cggcggccac cgctgcggct gcgcctcaca
2881 ctacaccctg gaccccagca gccgcaactg cagcccgccc accaccttct tgctgttcag
2941 ccagaaatct gccatcagtc ggatgatccc ggacgaccag cacagcccgg atctcatcct
3001 gcccctgcat ggactgagga acgtcaaagc catcgactat gacccactgg acaagttcat
3061 ctactgggtg gatgggcgcc agaacatcaa gcgagccaag gacgacggga cccagccctt
3121 tgttttgacc tctctgagcc aaggccaaaa cccagacagg cagccccacg acctcagcat
3181 cgacatctac agccggacac tgttctggac gtgcgaggcc accaatacca tcaacgtcca
3241 caggctgagc ggggaagcca tgggggtggt gctgcgtggg gaccgcgaca agcccagggc
3301 catcgtcgtc aacgcggagc gagggtacct gtacttcacc aacatgcagg accgggcagc
3361 caagatcgaa cgcgcagccc tggacggcac cgagcgcgag gtcctcttca ccaccggcct
3421 catccgccct gtggccctgg tggtggacaa cacactgggc aagctgttct gggtggacgc
3481 ggacctgaag cgcattgaga gctgtgacct gtcaggggcc aaccgcctga ccctggagga
3541 cgccaacatc gtgcagcctc tgggcctgac catccttggc aagcatctct actggatcga
3601 ccgccagcag cagatgatcg agcgtgtgga gaagaccacc ggggacaagc ggactcgcat
3661 ccagggccgt gtcgcccacc tcactggcat ccatgcagtg gaggaagtca gcctggagga
3721 gttctcagcc cacccatgtg cccgtgacaa tggtggctgc tcccacatct gtattgccaa
3781 gggtgatggg acaccacggt gctcatgccc agtccacctc gtgctcctgc agaacctgct
3841 gacctgtgga gagccgccca cctgctcccc ggaccagttt gcatgtgcca caggggagat
3901 cgactgtatc cccggggcct ggcgctgtga cggctttccc gagtgcgatg accagagcga
3961 cgaggagggc tgccccgtgt gctccgccgc ccagttcccc tgcgcgcggg gtcagtgtgt
4021 ggacctgcgc ctgcgctgcg acggcgaggc agactgtcag gaccgctcag acgaggcgga
4081 ctgtgacgcc atctgcctgc ccaaccagtt ccggtgtgcg agcggccagt gtgtcctcat
4141 caaacagcag tgcgactcct tccccgactg tatcgacggc tccgacgagc tcatgtgtga
4201 aatcaccaag ccgccctcag acgacagccc ggcccacagc agtgccatcg ggcccgtcat
4261 tggcatcatc ctctctctct tcgtcatggg tggtgtctat tttgtgtgcc agcgcgtggt
4321 gtgccagcgc tatgcggggg ccaacgggcc cttcccgcac gagtatgtca gcgggacccc
4381 gcacgtgccc ctcaatttca tagccccggg cggttcccag catggcccct tcacaggcat
4441 cgcatgcgga aagtccatga tgagctccgt gagcctgatg gggggccggg gcggggtgcc
4501 cctgtacgac cggaaccacg tcacaggggc ctcgtccagc agctcgtcca gcacgaaggc
4561 cacgctgtac ccgccgatcc tgaacccgcc gccctccccg gccacggacc cctccctgta
4621 caacatggac atgttctact cttcaaacat tccggccact gcgagaccgt acaggcccta
4681 catcattcga ggaatggcgc ccccgacgac gccctgcagc accgacgtgt gtgacagcga
4741 ctacagcgcc agccgctgga aggccagcaa gtactacctg gatttgaact cggactcaga
4801 cccctatcca cccccaccca cgccccacag ccagtacctg tcggcggagg acagctgccc
4861 gccctcgccc gccaccgaga ggagctactt ccatctcttc ccgccccctc cgtccccctg
4921 cacggactca tcctgacctc ggccgggcca ctctggcttc tctgtgcccc tgtaaatagt
4981 tttaaatatg aacaaagaaa aaaatatatt ttatgattta aaaaataaat ataattggga
5041 ttttaaaaac atgagaaatg tgaactgtga tggggtgggc agggctggga gaactttgta
5101 cagtggagaa atatttataa actcgtgccg aattc
//