LOCUS AF074924 3188 bp mRNA linear HUM 20-FEB-2001
DEFINITION Homo sapiens heparan sulfate N-deacetylase/N-sulfotransferase 3
mRNA, complete cds.
ACCESSION AF074924
VERSION AF074924.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3188)
AUTHORS Aikawa,J. and Esko,J.D.
TITLE Molecular cloning and expression of a third member of the heparan
sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family
JOURNAL J. Biol. Chem. 274 (5), 2690-2695 (1999)
PUBMED 9915799
REFERENCE 2 (bases 1 to 3188)
AUTHORS Aikawa,J., Grobe,K., Tsujimoto,M. and Esko,J.D.
TITLE Multiple isozymes of heparan sulfate/heparin GlcNAc
N-deacetylase/GlcN N-sulfotransferase. Structure and activity of
the fourth member, NDST4
JOURNAL J. Biol. Chem. 276 (8), 5876-5882 (2001)
PUBMED 11087757
REFERENCE 3 (bases 1 to 3188)
AUTHORS Aikawa,J. and Esko,J.D.
TITLE Direct Submission
JOURNAL Submitted (29-JUN-1998) Cancer Center, University of California,
San Diego, 9500 Gilman Dr., La Jolla, CA 92093-0687, USA
FEATURES Location/Qualifiers
source 1..3188
/db_xref="H-InvDB:HIT000065999"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q26-q27"
/tissue_type="brain"
/dev_stage="infant; fetus"
CDS 404..3025
/codon_start=1
/product="heparan sulfate N-deacetylase/N-sulfotransferase
3"
/protein_id="AAD15978.1"
/translation="MSFIMKLHRHFQRTVILLATFCMVSIIISAYYLYSGYKQENELS
ETASEVDCGDLQHLPYQLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESS
RFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVG
VIGFHKTSEKSVQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGT
DWTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNL
NFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQN
LLRAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHN
ESSLVEQMILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTE
EYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFT
VVLNPISIFMTHLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFP
DQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSN
SPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEEAPKRAA
SLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQK
RCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEA
LTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHK
LGQPLPSWLRQELQKVR"
BASE COUNT 930 a 699 c 660 g 899 t
ORIGIN
1 ccggtccctt ggcgacgggt cttgcatgtg acactcttgc cctctagtgc ctcaccagct
61 tggtagcagt ttgatggcta atattaataa gatgttacat aacatgagag tactgggcca
121 ggactggtgt tgctaccact tgtaaagtca aaaagcctga gccgatggta acgagtggta
181 ctgtttccgt ttcttttcca tctattgcaa ctttctcaag cattttcagc tctgaacttt
241 aattccagac tgtattttct gtgagtcctg atcaagtgat acaaatgagc tgcaatggtg
301 acataaactc ttgacagaga ttggaaaagt agctggaaca ccatcttttc ttttaacttt
361 ttatggtgct tctgttggca tagttgggga aagcacctac aacatgagtt ttatcatgaa
421 gcttcacaga cactttcaaa gaacagtcat tctgcttgcc actttttgta tggtgagcat
481 tatcatttct gcttactacc tgtacagtgg ctacaaacag gaaaatgaac tctctgagac
541 ggcttcagaa gttgactgtg gcgacctcca acacctacca tatcaactaa tggaagtgaa
601 agcaatgaag ctttttgatg cctcaaggac agaccccaca gtcctagtat ttgtagagag
661 ccagtactca tctcttggtc aagacatcat tatgattcta gaatcaagta gattccagta
721 tcacattgaa attgcccctg gaaagggaga tctcccagtg cttatagaca aaatgaaagg
781 caaatacatt ctcattattt atgagaatat tttaaagtat ataaatatgg attcctggaa
841 tcgaagcctt ctagataaat actgtgtaga atatggtgtg ggtgtcattg gattccacaa
901 aactagtgag aagagtgtac agagctttca gttaaaaggt ttcccttttt ccatatatgg
961 aaatcttgca gtaaaagatt gttgtattaa tcctcattct ccattgattc gtgtgaccaa
1021 atcttccaag cttgaaaaag gttctttacc tggaactgac tggacagttt ttcagattaa
1081 tcattcagcc tatcaaccag taatatttgc caaagtaaag accccagaaa acctttctcc
1141 ttccatctct aaaggtgctt tttatgccac tattatacat gacctggggc ttcatgatgg
1201 aattcaaagg gttctttttg gcaacaactt gaacttttgg ctgcacaagc tcatcttcat
1261 agatgccatc tccttcttat cagggaagag gctgacattg tccttggaca ggtacattct
1321 tgtggatatt gatgatatat ttgtgggaaa agagggaaca agaatgaaca ccaatgatgt
1381 aaaggccctg cttgatactc agaatctttt gcgtgcacaa atcacaaatt ttacattcaa
1441 cctgggattt tcagggaaat tttaccatac aggaactgaa gaggaagatg aaggagatga
1501 ctgtctgttg gggtctgtgg atgagttctg gtggtttcct cacatgtgga gccatatgca
1561 gccccacctc ttccacaatg agtcatcttt ggtggagcag atgattctca acaaaaaatt
1621 tgccttagag cacggcattc caacggacat gggctacgct gtggcccctc accattcggg
1681 cgtctaccct gtacatgttc agctttatga ggcctggaag aaggtctgga atattaaaat
1741 caccagcact gaagaatatc cacatctgaa gccagctaga taccggaggg gttttatcca
1801 caaaaacatc atggttctcc caagacaaac ctgtgggctt ttcactcaca ccattttcta
1861 caaagaatat ccagggggtc ctaaagagct ggataagagt atccaaggag gagaactttt
1921 cttcactgtc gtcctcaacc ctatcagcat tttcatgacc catttgtcca actatgggaa
1981 tgaccgactg ggattatata catttgttaa tctggccaac tttgtgaaga gctggaccaa
2041 cctgcgactt cagactctgc ctccagtaca actggcccac aagtattttg agctgtttcc
2101 tgatcagaaa gaccctctct ggcagaatcc ttgcgatgac aaacgccaca gagacatttg
2161 gtctaaagaa aaaacttgtg atcgcttacc aaaattcttg gtaataggac cccagaaaac
2221 tggtaccact gctttgtatt tgttcctggt tatgcatcct tccatcctta gtaactcccc
2281 cagcccaaaa acctttgagg aggtacagtt ctttaataga aataactacc acagggggat
2341 tgattggtat atggatttct tcccagtccc atctaatgtc actaccgact ttttgtttga
2401 gaagagtgcc aattacttcc actcagagga agcccctaaa agagctgctt ctctggttcc
2461 caaagccaag attatcacca ttctcattga cccttcagac cgagcatact cctggtacca
2521 gcatcagcga tcacatgaag accctgcagc tctgaagttt agcttctacg aagtgatctc
2581 agcagggccc cgtgcaccct cggagctcag agccttgcag aagagatgtt tggtcccggg
2641 gtggtatgcc agccacatcg agagatggct tgtttatttc cccccatttc agttgctaat
2701 tattgatggg caacaactaa gaactgatcc tgctacagtg atggatgaag tacagaagtt
2761 tctaggagtc ttgcctcatt ataattactc agaagcttta acgtttgatt ctcataaagg
2821 tttctggtgt cagttactgg aagaaggtaa aacaaaatgc cttggaaaga gcaaaggaag
2881 aaaataccct ccaatggatt ctgatagcag gacatttctg tcaagctact atcgagatca
2941 caacgtggaa ctctcaaagc tgctgcacaa actgggtcag cctctgccat cctggctgag
3001 acaggagctg cagaaagtaa gatagcactg agagaaaact tgagacttca tcgtccatgt
3061 agaacacacc ttttccaaag cttccagaag ctaccaaaag gcagttgaaa aatatacctc
3121 ttcaaatgag aaaaaagaac agtttcttcc atgtgctggc acgtggatga ttagaaaaaa
3181 aaaaaaaa
//