LOCUS AF074015 3884 bp mRNA linear HUM 16-AUG-1998
DEFINITION Homo sapiens integrin subunit alpha 10 precursor, mRNA, complete
cds.
ACCESSION AF074015
VERSION AF074015.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3884)
AUTHORS Camper,L., Hellman,U. and Lundgren-Akerlund,E.
TITLE Isolation, cloning, and sequence analysis of the integrin subunit
alpha10, a beta1-associated collagen binding integrin expressed on
chondrocytes
JOURNAL J. Biol. Chem. 273 (32), 20383-20389 (1998)
PUBMED 9685391
REFERENCE 2 (bases 1 to 3884)
AUTHORS Camper,L., Hellman,U. and Lundgren-Akerlund,E.
TITLE Direct Submission
JOURNAL Submitted (24-JUN-1998) Cell and Molecular Biology, Cell and Matrix
Biology, P.O BOX 94, Lund S-221 00, Sweden
FEATURES Location/Qualifiers
source 1..3884
/db_xref="H-InvDB:HIT000065979"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="chondrocyte"
CDS 22..3525
/codon_start=1
/product="integrin subunit alpha 10 precursor"
/protein_id="AAC31952.1"
/translation="MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYS
VLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHP
AVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQ
RCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWS
LGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTD
GESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFF
FNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDGILFGMVG
AYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSMLLRGGRRLFLSG
APRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAA
PMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFAD
VAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGD
DLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTAALCF
QVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPRRLRLSVGNVTCEQLH
FHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTD
LVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSIIFSRNLHLASLT
PQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFGKLTAS
SDSLERNGTLQENTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTL
RVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPVHPE
ELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTF
ELGTEEGSVLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWK
LGFFAHKKIPEEEKREEKLEQ"
misc_feature 22..3315
/note="Region: extracellular"
sig_peptide 22..87
mat_peptide 88..3522
/product="integrin subunit alpha 10"
misc_feature 247..249
/note="glycosylation site"
misc_feature 439..1032
/note="Region: I-domain"
misc_feature 655..657
/note="glycosylation site"
misc_feature 961..963
/note="glycosylation site"
misc_feature 1045..1047
/note="glycosylation site"
misc_feature 2152..2154
/note="glycosylation site"
misc_feature 2242..2244
/note="glycosylation site"
misc_feature 2470..2472
/note="glycosylation site"
misc_feature 2716..2718
/note="glycosylation site"
misc_feature 3007..3009
/note="glycosylation site"
misc_feature 3070..3072
/note="glycosylation site"
misc_feature 3316..3390
/note="Region: transmembrane"
misc_feature 3391..3456
/note="Region: cytoplasmic"
BASE COUNT 858 a 1031 c 1078 g 917 t
ORIGIN
1 caggtcagaa accgatcagg catggaactc cccttcgtca ctcacctgtt cttgcccctg
61 gtgttcctga caggtctctg ctcccccttt aacctggatg aacatcaccc acgcctattc
121 ccagggccac cagaagctga atttggatac agtgtcttac aacatgttgg gggtggacag
181 cgatggatgc tggtgggcgc cccctgggat gggccttcag gcgaccggag gggggacgtt
241 tatcgctgcc ctgtaggggg ggcccacaat gccccatgtg ccaagggcca cttaggtgac
301 taccaactgg gaaattcatc tcatcctgct gtgaatatgc acctggggat gtctctgtta
361 gagacagatg gtgatggggg attcatggcc tgtgcccctc tctggtctcg tgcttgtggc
421 agctctgtct tcagttctgg gatatgtgcc cgtgtggatg cttcattcca gcctcaggga
481 agcctggcac ccactgccca acgctgccca acatacatgg atgttgtcat tgtcttggat
541 ggctccaaca gcatctaccc ctggtctgaa gttcagacct tcctacgaag actggtaggg
601 aaactgttta ttgacccaga acagatacag gtgggactgg tacagtatgg ggagagccct
661 gtacatgagt ggtccctggg agatttccga acgaaggaag aagtggtgag agcagcaaag
721 aacctcagtc ggcgggaggg acgagaaaca aagactgccc aagcaataat ggtggcctgc
781 acagaagggt tcagtcagtc ccatgggggc cgacccgagg ctgccaggct actggtggtt
841 gtcactgatg gagagtccca tgatggagag gagcttcctg cagcactaaa ggcctgtgag
901 gctggaagag tgacacgcta tgggattgca gtccttggtc actacctccg gcggcagcga
961 gatcccagct ctttcctgag agaaattaga actattgcca gtgatccaga tgagcgattc
1021 ttcttcaatg tcacagatga ggctgctctg actgacattg tggatgcact aggagatcgg
1081 atttttggcc ttgaagggtc ccatgcagaa aacgaaagct cctttgggct ggaaatgtct
1141 cagattggtt tctccactca tcggctaaag gatgggattc tttttgggat ggtgggggcc
1201 tatgactggg gaggctctgt gctatggctt gaaggaggcc accgcctttt ccccccacga
1261 atggcactgg aagacgagtt cccccctgca ctgcagaacc atgcagccta cctgggttac
1321 tctgtttctt ccatgctttt gcggggtgga cgccgcctgt ttctctctgg ggctcctcga
1381 tttagacatc gaggaaaagt catcgccttc cagcttaaga aagatggggc tgtgagggtt
1441 gcccagagcc tccaggggga gcagattggt tcatactttg gcagtgagct ctgcccattg
1501 gatacagata gggatggaac aactgatgtc ttacttgtgg ctgcccccat gttcctggga
1561 ccccagaaca aggaaacagg acgtgtttat gtgtatctgg taggccagca gtccttgctg
1621 accctccaag gaacacttca gccagaaccc ccccaggatg ctcggtttgg ctttgccatg
1681 ggagctcttc ctgatctgaa ccaagatggt tttgctgatg tggctgtggg ggcgcctctg
1741 gaagatgggc accagggagc actgtacctg taccatggaa cccagagtgg agtcaggccc
1801 catcctgccc agaggattgc tgctgcctcc atgccacatg ccctcagcta ctttggccga
1861 agtgtggatg gtcggctaga tctggatgga gatgatctgg tcgatgtggc tgtgggtgcc
1921 cagggggcag ccatcctgct cagctcccgg cccattgtcc atctgacccc atcactggag
1981 gtgaccccac aggccatcag tgtggttcag agggactgta ggcggcgagg ccaagaagca
2041 gtctgtctga ctgcagccct ttgcttccaa gtgacctccc gtactcctgg tcgctgggat
2101 caccaattct acatgaggtt caccgcatca ctggatgaat ggactgctgg ggcacgtgca
2161 gcatttgatg gctctggcca gaggttgtcc cctcggaggc tccggctcag tgtggggaat
2221 gtcacttgtg agcagctaca cttccatgtg ctggatacat cagattacct ccggccagtg
2281 gccttgactg tgacctttgc cttggacaat actacaaagc cagggcctgt gctgaatgag
2341 ggctcaccca cctctataca aaagctggtc cccttctcaa aggattgtgg ccctgacaat
2401 gaatgtgtca cagacctggt gcttcaagtg aatatggaca tcagaggctc caggaaggcc
2461 ccatttgtgg ttcgaggtgg ccggcggaaa gtgctggtat ctacaactct ggagaacaga
2521 aaggaaaatg cttacaatac gagcctgagt atcatcttct ctagaaacct ccacctggcc
2581 agtctcactc ctcagagaga gagcccaata aaggtggaat gtgccgcccc ttctgctcat
2641 gcccggctct gcagtgtggg gcatcctgtc ttccagactg gagccaaggt gacctttctg
2701 ctagagtttg agtttagctg ctcctctctc ctgagccagg tctttgggaa gctgactgcc
2761 agcagtgaca gcctggagag aaatggcacc cttcaagaaa acacagccca gacctcagcc
2821 tacatccaat atgagcccca cctcctgttc tctagtgagt ctaccctgca ccgctatgag
2881 gttcacccat atgggaccct cccagtgggt cctggcccag aattcaaaac cactctcagg
2941 gttcagaacc taggctgcta tgtggtcagt ggcctcatca tctcagccct ccttccagct
3001 gtggcccatg ggggcaatta cttcctatca ctgtctcaag tcatcactaa caatgcaagc
3061 tgcatagtgc agaacctgac tgaaccccca ggcccacctg tgcatccaga ggagcttcaa
3121 cacacaaaca gactgaatgg gagcaatact cagtgtcagg tggtgaggtg ccaccttggg
3181 cagctggcaa aggggactga ggtctctgtt ggactattga ggctggttca caatgaattt
3241 ttccgaagag ccaagttcaa gtccctgacg gtggtcagca cctttgagct gggaaccgaa
3301 gagggcagtg tcctacagct gactgaagcc tcccgttgga gtgagagcct cttggaggtg
3361 gttcagaccc ggcctatcct catctccctg tggatcctca taggcagtgt cctgggaggg
3421 ttgctcctgc ttgctctcct tgtcttctgc ctgtggaagc ttggcttctt tgcccataag
3481 aaaatccctg aggaagaaaa aagagaagag aagttggagc aatgaatgta gaataagggt
3541 ctagaaagtc ctccctggca gctttcttca agagacttgc ataaaagcag aggtttgggg
3601 gctcagatgg gacaagaagc cgcctctgga ctatctcccc agaccagcag cctgacttga
3661 cttttgagtc ctagggatgc tgctggctag agatgaggct ttacctcaga caagaagagc
3721 tggcaccaaa actagccatg ctcccaccct ctgcttccct cctcctcgtg atcctggttc
3781 catagccaac actggggctt ttgtttgggg tccttttatc cccaggaatc aataattttt
3841 ttgcctagga aaaaaaaaag cggccgcgaa ttcgatatca agct
//