LOCUS AF073887 2005 bp mRNA linear HUM 12-MAR-1999
DEFINITION Homo sapiens tetratricopeptide repeat protein 4 (TTC4) mRNA,
complete cds.
ACCESSION AF073887
VERSION AF073887.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2005)
AUTHORS Su,G., Roberts,T. and Cowell,J.K.
TITLE TTC4, a novel human gene containing the tetratricopeptide repeat
and mapping to the region of chromosome 1p31 that is frequently
deleted in sporadic breast cancer
JOURNAL Genomics 55 (2), 157-163 (1999)
PUBMED 9933562
REFERENCE 2 (bases 1 to 2005)
AUTHORS Su,G., Roberts,T. and Cowell,J.K.
TITLE Direct Submission
JOURNAL Submitted (23-JUN-1998) Neurosciences, Cleveland Clinic Foundation,
9500 Euclid Avenue, Cleveland, OH 44143, USA
FEATURES Location/Qualifiers
source 1..2005
/db_xref="H-InvDB:HIT000065966"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31"
/tissue_type="brain"
/dev_stage="fetus"
gene 1..2005
/gene="TTC4"
CDS 34..1104
/gene="TTC4"
/codon_start=1
/product="tetratricopeptide repeat protein 4"
/protein_id="AAD19853.1"
/translation="MEQPGQDPTSDDVMDSFLEKFQSQPYRGGFHEDQWEKEFEKVPL
FMSRAPSEIDPRENPDLACLQSIIFDEERSPEEQAKTYKDEGNDYFKEKDYKKAVISY
TEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALC
HLELIHFAEAVNWCDEGLQIDAKEKKLLEMRAKADKLKRIEQRDVRKANLKEKKERNQ
NEALLQAIKARNIRLSEAACEDEDSASEGLGELFLDGLSTENPHGARLSLDGQGRLSW
PVLFLYPEYAQSDFISAFHEDSRFIDHLMVMFGETPSWDLEQKYCLIIWRSTLRMRTG
QNYTGCLPRAPCYRFYSTRGTL"
misc_feature 379..723
/gene="TTC4"
/note="Region: tetratricopeptide repeat motifs"
misc_feature 823..1101
/gene="TTC4"
/note="Region: coiled coil domain"
BASE COUNT 542 a 453 c 503 g 507 t
ORIGIN
1 ctgggacccg ggctggaagg cagggcatca gctatggaac aacctgggca ggatcccacc
61 tcagacgacg tcatggactc gttcctggaa aagttccaga gccagcctta ccgtggcggc
121 tttcatgagg accagtggga gaaggaattt gaaaaggtcc ccctatttat gtcgagagcg
181 ccatcagaaa ttgatcccag ggagaatcct gacttggctt gtctccagtc aattattttt
241 gatgaggagc gttctccaga agaacaggcc aagacctata aagatgaggg caatgattac
301 tttaaagaaa aagactacaa gaaagctgta atttcataca ctgaaggctt aaagaagaaa
361 tgtgcagatc ctgatttgaa tgctgtcctt tataccaacc gggcagcagc acagtactat
421 ctgggcaatt ttcgttctgc tctcaatgat gtgacagctg ccagaaagct aaaaccctgc
481 cacctcaaag caataataag aggtgcctta tgccatctgg aactgataca ctttgccgag
541 gccgtgaact ggtgtgatga gggactgcaa atagatgcca aagagaagaa gcttctggaa
601 atgagggcta aagcagacaa gctgaagcga attgaacaga gggatgtgag gaaagccaac
661 ttgaaagaaa agaaggagag gaatcagaat gaggctttac tccaggccat caaggctagg
721 aatatcaggc tctcagaagc tgcctgtgag gatgaagatt cagcctcaga aggtctaggt
781 gagcttttcc tggatggact cagcactgag aacccccatg gagccaggct gagtctagat
841 ggccagggca ggctgagctg gcctgtgctc tttctgtacc cagagtatgc ccagtcggac
901 ttcatctctg cttttcatga ggactccagg tttattgatc atctaatggt gatgtttggt
961 gaaacacctt cttgggacct agagcaaaaa tattgcctga taatttggag gtctactttg
1021 aggatgagga cagggcagaa ctataccggg tgcctgccaa gagcaccttg ctacaggttc
1081 tacagcacca gaggtacttt gtaaaagccc tgacaccagc atttttggtc tgtgtaggat
1141 cctctccttt ttgcaagaat tttctccggg ggagaaaggt gtaccagata cgatgactaa
1201 gccagggccc ctggatctcc tcccttaccc tcctctgctg ggaacctagc acacctgaat
1261 cagctggaca tactgctgga gtccagtgct ttctttccgt caccctgggg atagtccttc
1321 ctggcatcgt ggtgggggag gagcctctgg cttccctaaa ctgcagctct ctggctggtc
1381 ttcactttcc tcagttgata taaaactctg gtcttggcca tgatgtcctt ggattccatc
1441 gctaaaggga ccatctgctg cagttaccac agcaactgac ttgagcggca cctggtctgt
1501 ggagatggac tcaggatcca gtgacatgat tctgaacttt tgtggagttt gacaccttag
1561 agaagctacc cctcaaactg cacatctaca cacaaacaaa caatgcatag gattccaagg
1621 ctttaaagct gagagaccct ggcctcaagt tatttcatgc gcacagaggg aagccatgtg
1681 gggttgctga agatgccttg aggtgaaatg ggggcaggaa agccacatct tgctctgcat
1741 ttataaagac cgtacaaact cagatccttg gtacccctaa aaagattgcc aattttcttc
1801 atctttgcca tatggaggac tgtgacagac tttggacagt ggcctcttga gttcctctgc
1861 agttttgaca tttaggattt tgtgtctttt aaactggaaa atcttctagc atgttgggtt
1921 gttacagagt atatttttgt ctgcagctgt ttgttgcccc attcctaaga ggagtttatc
1981 catcctgaaa aaaaaaaaaa aaaaa
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