LOCUS AF072873 2697 bp mRNA linear HUM 05-APR-2004
DEFINITION Homo sapiens frizzled 6 mRNA, complete cds.
ACCESSION AF072873
VERSION AF072873.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2697)
AUTHORS Bafico,A., Gazit,A., Pramila,T., Finch,P.W., Yaniv,A. and
Aaronson,S.A.
TITLE Interaction of frizzled related protein (FRP) with Wnt ligands and
the frizzled receptor suggests alternative mechanisms for FRP
inhibition of Wnt signaling
JOURNAL J. Biol. Chem. 274 (23), 16180-16187 (1999)
PUBMED 10347172
REFERENCE 2 (bases 1 to 2697)
AUTHORS Gazit,A., Yaniv,A. and Aaronson,S.A.
TITLE Direct Submission
JOURNAL Submitted (18-JUN-1998) Derald H. Ruttenberg Cancer Center, The
Mount Sinai Medical Center, One Gustave L. Levy Place, East
Building, New York, NY 101029-6574, USA
FEATURES Location/Qualifiers
source 1..2697
/db_xref="H-InvDB:HIT000065916"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 281..2401
/function="Wnt receptor"
/codon_start=1
/product="frizzled 6"
/protein_id="AAD41637.1"
/translation="MEMFTFLLTCIFLPLLRGHSLFTCEPITVPRCMKMAYNMTFFPN
LMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVPTCIEQIHVVPPCRKLCEKV
YSDCKKLIDTFGIRWPEELECDRLQYCDETVPVTFDPHTEFLGPQKKTEQVQRDIGFW
CPRHLKTSGGQGYKFLGIDQCAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFL
TFLIDVRRFRYPERPIIYYSVCYSIVSLMYFIGFLLGDSTACNKADEKLELGDTVVLG
SQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAGRKWSCEAIEQKAVWFHAVAWGT
PGFLTVMLLALNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVGLSLLLAGIIS
LNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWV
SDHCRQYHIPCPYQAKAKARPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWAGFFK
RNRKRDPISESRRVLQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISKSMGTSTGATA
NHGTSAVAITSHDYLGQETLTEIQTSPETSMREVKADGASTPRLREQDCGEPASPAAS
ISRLSGEQVDGKGQAGSVSESARSEGRISPKSDITDTGLAQSNNLQVPSSSEPSSLKG
STSLLVHPVSGVRKEQGGGCHSDT"
BASE COUNT 781 a 534 c 608 g 774 t
ORIGIN
1 atacggatcc gtcgacggcc attaccaatc gcgaaaccac gcaaccccgg agccgtctca
61 ggtccctggg gggaacggtg ggttagacgg ggacgggaag ggacagcggc cttcgaccgc
121 cccccgagta attgacccag gactcatttt caggaaagcc tgaaaatgag taaaatagtg
181 aaatgaggaa tttgaacatt ttatctttgg atggggatct tctgaggatg caaagagtga
241 ttcatccaag ccatgtggta aaatcaggaa tttgaagaaa atggagatgt ttacattttt
301 gttgacgtgt atttttctac ccctcctaag agggcacagt ctcttcacct gtgaaccaat
361 tactgttccc agatgtatga aaatggccta caacatgacg tttttcccta atctgatggg
421 tcattatgac cagagtattg ccgcggtgga aatggagcat tttcttcctc tcgcaaatct
481 ggaatgttca ccaaacattg aaactttcct ctgcaaagca tttgtaccaa cctgcataga
541 acaaattcat gtggttccac cttgtcgtaa actttgtgag aaagtatatt ctgattgcaa
601 aaaattaatt gacacttttg ggatccgatg gcctgaggag cttgaatgtg acagattaca
661 atactgtgat gagactgttc ctgtaacttt tgatccacac acagaatttc ttggtcctca
721 gaagaaaaca gaacaagtcc aaagagacat tggattttgg tgtccaaggc atcttaagac
781 ttctggggga caaggatata agtttctggg aattgaccag tgtgcgcctc catgccccaa
841 catgtatttt aaaagtgatg agctagagtt tgcaaaaagt tttattggaa cagtttcaat
901 attttgtctt tgtgcaactc tgttcacatt ccttactttt ttaattgatg ttagaagatt
961 cagataccca gagagaccaa ttatatatta ctctgtctgt tacagcattg tatctcttat
1021 gtacttcatt ggatttttgc tgggcgatag cacagcctgc aataaggcag atgagaagct
1081 agaacttggt gacactgttg tcctaggctc tcaaaataag gcttgcaccg ttttgttcat
1141 gcttttgtat tttttcacaa tggctggcac tgtgtggtgg gtgattctta ccattacttg
1201 gttcttagct gcaggaagaa aatggagttg tgaagccatc gagcaaaaag cagtgtggtt
1261 tcatgctgtt gcatggggaa caccaggttt cctgactgtt atgcttcttg ctctgaacaa
1321 agttgaagga gacaacatta gtggagtttg ctttgttggc ctttatgacc tggatgcttc
1381 tcgctacttt gtactcttgc cactgtgcct ttgtgtgttt gttgggctct ctcttctttt
1441 agctggcatt atttccttaa atcatgttcg acaagtcata caacatgatg gccggaacca
1501 agaaaaacta aagaaattta tgattcgaat tggagtcttc agcggcttgt atcttgtgcc
1561 attagtgaca cttctcggat gttacgtcta tgagcaagtg aacaggatta cctgggagat
1621 aacttgggtc tctgatcatt gtcgtcagta ccatatccca tgtccttatc aggcaaaagc
1681 aaaagctcga ccagaattgg ctttatttat gataaaatac ctgatgacat tgattgttgg
1741 catctctgct gtcttctggg ttggaagcaa aaagacatgc acagaatggg ctgggttttt
1801 taaacgaaat cgcaagagag atccaatcag tgaaagtcga agagtactac aggaatcatg
1861 tgagtttttc ttaaagcaca attctaaagt taaacacaaa aagaagcact ataaaccaag
1921 ttcacacaag ctgaaggtca tttccaaatc catgggaacc agcacaggag ctacagcaaa
1981 tcatggcact tctgcagtag caattactag ccatgattac ctaggacaag aaactttgac
2041 agaaatccaa acctcaccag aaacatcaat gagagaggtg aaagcggacg gagctagcac
2101 ccccaggtta agagaacagg actgtggtga acctgcctcg ccagcagcat ccatctccag
2161 actctctggg gaacaggtcg acgggaaggg ccaggcaggc agtgtatctg aaagtgcgcg
2221 gagtgaagga aggattagtc caaagagtga tattactgac actggcctgg cacagagcaa
2281 caatttgcag gtccccagtt cttcagaacc aagcagcctc aaaggttcca catctctgct
2341 tgttcaccca gtttcaggag tgagaaaaga gcagggaggt ggttgtcatt cagatacttg
2401 aagaacattt tctctcgtta ctcagaagca aatttgtgtt acactggaag tgacctatgc
2461 actgttttgt aagaatcact gttacgttct tcttttgcac ttaaagttgc attgcctact
2521 gttatactgg aaaaaataga gttcaagaat aatatgactc atttcacaca aaggttaatg
2581 acaacaatat acctgaaaac agaaatgttg caggttaata atattttttt aatagtgtgg
2641 gaagacagag ttagaggaat cttccttttc tatttatgaa gatctactct tggtaga
//