LOCUS AF072872 2531 bp mRNA linear HUM 24-NOV-2000
DEFINITION Homo sapiens frizzled 1 mRNA, complete cds.
ACCESSION AF072872
VERSION AF072872.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2531)
AUTHORS Gazit,A., Yaniv,A., Bafico,A., Pramila,T., Igarashi,M.,
Kitajewski,J. and Aaronson,S.A.
TITLE Human frizzled 1 interacts with transforming Wnts to transduce a
TCF dependent transcriptional response
JOURNAL Oncogene 18 (44), 5959-5966 (1999)
PUBMED 10557084
REFERENCE 2 (bases 1 to 2531)
AUTHORS Yaniv,A., Gazit,A. and Aaronson,S.A.
TITLE Direct Submission
JOURNAL Submitted (18-JUN-1998) Derald H. Ruttenberg Cancer Center, The
Mount Sinai Medical Center, One Gustave L. Levy Place, East
Building, New York, NY 10029-6574, USA
FEATURES Location/Qualifiers
source 1..2531
/db_xref="H-InvDB:HIT000065915"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 401..2347
/function="Wnt receptor"
/codon_start=1
/product="frizzled 1"
/protein_id="AAD41636.1"
/translation="MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRP
PVDPRRLARQLLLLLWLLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPPQQQQSGQQ
YNGERGISVPDHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKV
QCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEK
FPVHGAGELCVGQNTSDKGTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFS
CPRALKVPSYLNYHFLGEKDCGAPCEPTKVYGLMYFGPEELRFSRTWIGIWSVLCCAS
TLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGAR
TVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHL
AAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLL
AGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQW
ERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWS
GKTLNSWRKFYTRLTNSKQGETTV"
BASE COUNT 426 a 842 c 844 g 419 t
ORIGIN
1 gacacaaatg gtcaggcggc ggcggcggag aaggaggcgg aggcgcaggg gggagccgag
61 cccgctgggc tgcggagagt tgcgctcttt acggggccgc ggccactagc gcggcgccgc
121 cagccgggag ccagcgagcc gagggccagg aaggcgggac agaccccggc gcgcccgagc
181 cacccgggtt ctccccgccg cccgcgcttc atgaatcgca agtttccgcg gcggcggcgg
241 ctgcggtacg cagaacagga gccgggggag cgggccgaaa gcggcttggg ctcgacggag
301 ggcaccggcg cagaggtctc cctggccgca gggggagccg ccgccggccg tgcccctggc
361 agccccagcg gagcggcgcc aagagaggag ccgagaaagt atggctgagg aggaggcgcc
421 taagaagtcc cgggccgccg gcggtggcgc gagctgggaa ctttgtgccg gggcgctctc
481 ggcccggctg gcggaggagg gcagcgggga cgccggtggc cgccgccgcc cgccagttga
541 cccccggcga ttggcgcgcc agctgctgct gctgctttgg ctgctggagg ctccgctgct
601 gctgggggtc cgggcccagg cggcgggcca ggggccaggc caggggcccg ggccggggca
661 gcaaccgccg ccgccgccgc ctcagcagca acagagcggg cagcagtaca acggcgagcg
721 gggcatctcc gtcccggacc acggctattg ccagcccatc tccatcccgc tgtgcacgga
781 catcgcgtac aaccagacca tcatgcccaa cctgctgggc cacacgaacc aggaggacgc
841 gggcctggag gtgcaccagt tctaccctct agtgaaagtg cagtgttccg ctgagctcaa
901 gttcttcctg tgctccatgt acgcgcccgt gtgcaccgtg ctagagcagg cgctgccgcc
961 ctgccgctcc ctgtgcgagc gcgcgcgcca gggctgcgag gcgctcatga acaagttcgg
1021 cttccagtgg ccagacacgc tcaagtgtga gaagttcccg gtgcacggcg ccggcgagct
1081 gtgcgtgggc cagaacacgt ccgacaaggg caccccgacg ccctcgctgc ttccagagtt
1141 ctggaccagc aaccctcagc acggcggcgg agggcaccgt ggcggcttcc cggggggcgc
1201 cggcgcgtcg gagcgaggca agttctcctg cccgcgcgcc ctcaaggtgc cctcctacct
1261 caactaccac ttcctggggg agaaggactg cggcgcacct tgtgagccga ccaaggtgta
1321 tgggctcatg tacttcgggc ccgaggagct gcgcttctcg cgcacctgga ttggcatttg
1381 gtcagtgctg tgctgcgcct ccacgctctt cacggtgctt acgtacctgg tggacatgcg
1441 gcgcttcagc tacccggagc ggcccatcat cttcttgtcc ggctgttaca cggccgtggc
1501 cgtggcctac atcgccggct tcctcctgga agaccgagtg gtgtgtaatg acaagttcgc
1561 cgaggacggg gcacgcactg tggcgcaggg caccaagaag gagggctgca ccatcctctt
1621 catgatgctc tacttcttca gcatggccag ctccatctgg tgggtgatcc tgtcgctcac
1681 ctggttcctg gcggctggca tgaagtgggg ccacgaagcc atcgaagcca actcacagta
1741 ttttcacctg gccgcctggg ctgtgccggc catcaagacc atcaccatcc tggcgctggg
1801 ccaggtggac ggcgatgtgc tgagcggagt gtgcttcgtg gggcttaaca acgtggacgc
1861 gctgcgtggc ttcgtgctgg cgcccctctt cgtgtacctg tttatcggca cgtcctttct
1921 gctggccggc tttgtgtcgc tcttccgcat ccgcaccatc atgaagcacg atggcaccaa
1981 gaccgagaag ctggagaagc tcatggtgcg cattggcgtc ttcagcgtgc tgtacactgt
2041 gccagccacc atcgtcatcg cctgctactt ctacgagcag gccttccggg accagtggga
2101 acgcagctgg gtggcccaga gctgcaagag ctacgctatc ccctgccctc acctccaggc
2161 gggcggaggc gccccgccgc acccgcccat gagcccggac ttcacggtct tcatgattaa
2221 gtaccttatg acgctgatcg tgggcatcac gtcgggcttc tggatctggt ccggcaagac
2281 cctcaactcc tggaggaagt tctacacgag gctcaccaac agcaaacaag gggagactac
2341 agtctgagac ccggggctca gcccatgccc aggcctcggc cggggcgcaa cgatccccca
2401 aagccagcgc cgtggagttc gtgccaatcc tgacatctcg aggtttcctc actaacaact
2461 ctctttcgca ggctcctttg aacaactcag ctcctgcaaa agcttccgtc cctgaagcaa
2521 aaggacacga a
//