LOCUS AF071309 6788 bp mRNA linear HUM 04-DEC-1998
DEFINITION Homo sapiens OPA-containing protein mRNA, complete cds.
ACCESSION AF071309
VERSION AF071309.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6788)
AUTHORS Philibert,R.A., King,B.H., Cook,E.H., Lee,Y.-H., Stubblefield,B.,
Damschroder-Williams,P., Dea,C., Palotie,A., Tengstroom,C.,
Martin,B.M. and Ginns,E.I.
TITLE Association of an X-chromosome dodecamer insertional variant allele
with mental retardation
JOURNAL Mol. Psychiatry 3 (4), 303-309 (1998)
PUBMED 9702738
REFERENCE 2 (bases 1 to 6788)
AUTHORS Philibert,R.A., King,B.H., Cook,E.H., Lee,Y.-H., Stubblefield,B.,
Damschroder-Williams,P., Dea,C., Palotie,A., Tengstroom,C.,
Martin,B.M. and Ginns,E.I.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-1998) Clinical Neuroscience Branch, NIMH, 49
Convent Drive Rm B1EE16, Bethesda, MD 20892-4405, USA
FEATURES Location/Qualifiers
source 1..6788
/db_xref="H-InvDB:HIT000065850_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq13"
CDS 472..6543
/note="HOPA"
/codon_start=1
/product="OPA-containing protein"
/protein_id="AAC83163.1"
/translation="MRAAWLIKMTCAYYAAISETKVKKRHVDPFMEWTQIITKYLWEQ
LQKMAEYYRPGPAGSGGCGSTIGPLPHDVEVAIRQWDYTEKLAMFMFQDGMLDRHEFL
TWVLECFEKIRPGEDELLKLLLPLLLRYSGEFVQSAYLSRRLAYFCTRRLALQLDGVS
SHSSHVISAQSTSTLPTTPAPQPPTSSTPSTPFSDLLMCPQHRPLVFGLSCILQTILL
CCPSALVWHYSLTDSRIKTGSPLDHLPIAPSNLPMPEGNSAFTQQVRAKLREIEQQIK
ERGQAVEVRWSFDKCQEATAGFTIGRVLHTLEVLDSHSFERSDFSNSLDSLCNRIFGL
GPSKDGHEISSDDDAVVSLLCEWAVSCKRSGRHRAMVVAKLLEKRQAEIEAERCGESE
AADEKGSIASGSLSAPSAPIFQDVLLQFLDTQAPMLTDPRSESERVEFFNLVLLFCEL
IRHDVFSHNMYTCTLISRGDLAFGAPGPRPPSPFDDPADDPEHKEAEGSSSSKLEDPG
LSESMDIDPSSSVLFEDMEKPDFSLFSPTMPCEGKGSPSPEKPDVEKEVKPPPKEKIE
GTLGVLYDQPRHVQYATHFPIPQEESCSHECNQRLVVLFGVGKQRDDARHAIKKITKD
ILKVLNRKGTAETDQLAPIVPLNPGDLTFLGGEDGQKRRRNRPEAFPTAEDIFAKFQH
LSHYDQHQVTAQVSRNVLEQITSFALGMSYHLPLVQHVQFIFDLMEYSLSISGLIDFA
IQLLNELSVVEAELLLKSSDLVGSYTTSLCLCIVAVLRHYHACLILNQDQMAQVFEGL
CGVVKHGMNRSDGSSAERCILAYLYDLYTSCSHLKNKFGELFSDFCSKVKNTIYCNVE
PSESNMRWAPEFMIDTLENPAAHTFTYTGLGKSLSENPANRYSFVCNALMHVCVGHHD
PDRVNDIAILCAELTGYCKSLSAEWLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFH
DSLATFVAILIARQCLLLEDLIRCAAIPSLLNAACSEQDSEPGARLTCRILLHLFKTP
QLNPCQSDGNKPTVGIRSSCDRHLLAASQNRIVDGAVFAVLKAVFVLGDAELKGSGFT
VTGGTEELPEEEGGGGSGGRRQGGRNISVETASLDVYAKYVLRSICQQEWVGERCLKS
LCEDSNDLQDPVLSSAQAQRLMQLICYPHRLLDNEDGENPQRQRIKRILQNLDQWTMR
QSSLELQLMIKQTPNNEMNSLLENIAKATIEVFQQSAETGSSSGSTASNMPSSSKTKP
VLSSLERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSM
SLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVHQIVNNWRDDQYLDDCKPKQLMHE
ALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDMQSNNELFTTVLDMLSVL
INGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGERQSDSLEKVRQLLPLPKQTRD
VITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPWDLFEGLKPSAPLSWGWF
GTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKA
PEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTEDYGMGPGRSGPYGVTVPPDLL
HHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLP
TTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQSQGMLGQSSVHQMTPSSSYGL
QTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPS
GYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQ
QQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQ
QQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPS
TNIFGRY"
BASE COUNT 1622 a 1937 c 1753 g 1476 t
ORIGIN
1 gcggccgcgt cgacggcggc cttcgggatc ttgagctacg aacaccggcc cctgaagcgg
61 ccgcggctgg ggcctcccga tgtttaccct caggacccca aacagaagga ggatgaactg
121 acggccttga atgtaaaaca aggtttcaat aaccagcctg ctgtctctgg ggatgagcat
181 ggcagtgcca agaacgtcag cttcaatcct gccaagatca gttccaactt cagcagcatt
241 attgcagaga aattacgttg taataccctt cctgacactg gtcgcaggaa gccccaagtg
301 aaccagaagg ataacttctg gctggtgact gcacgatccc agagtgccat taacacttgg
361 ttcactgact tggctggcac caagccactc acgcaactag ccaaaaaggt ccccattttc
421 agtaagaagg aagaggtgtt tgggtactta gccaaataca cagtgcctgt gatgcgggct
481 gcctggctca ttaagatgac ctgtgcctac tatgcagcaa tctctgagac caaggttaag
541 aagagacatg ttgacccttt catggaatgg actcagatca tcaccaagta cttatgggag
601 cagttacaga agatggctga atactaccgg ccagggcctg caggaagtgg gggctgtggt
661 tccacgatag ggcccttgcc ccatgatgta gaggtggcaa tccggcagtg ggattacacc
721 gagaagctgg ccatgttcat gtttcaggat ggaatgctgg acagacatga gttcctgacc
781 tgggtgcttg agtgttttga gaagatccgc cctggagagg atgaattgct taaactgctg
841 ctgcctctgc ttctccgata ctctggggaa tttgttcagt ctgcatacct gtcccgccgg
901 cttgcctact tctgtacacg gagactggcc ctgcagctgg atggtgtgag cagtcactca
961 tctcatgtta tatctgctca gtcaacaagc acgctaccca ccacccctgc tcctcagccc
1021 ccaactagca gcacaccctc gactcccttt agtgacctgc ttatgtgccc tcagcaccgg
1081 cccctggttt ttggcctcag ctgtatccta cagaccatcc tcctgtgctg tcctagtgcc
1141 ttggtttggc actactcact gactgatagc agaattaaga ccggctcacc acttgaccac
1201 ttgcctattg ccccgtccaa cctgcccatg ccagagggta acagtgcctt cactcagcag
1261 gtccgtgcaa agttgcggga gatcgagcag cagatcaagg agcggggaca ggcagttgaa
1321 gttcgctggt ctttcgataa atgccaggaa gctactgcag gcttcaccat tggacgggta
1381 cttcatactt tggaagtgct ggacagccat agttttgaac gctctgactt cagcaactct
1441 cttgactccc tttgtaaccg aatctttgga ttgggaccta gcaaggatgg gcatgagatc
1501 tcctcagatg atgatgctgt ggtgtcattg ctatgtgaat gggctgtcag ctgcaagcgt
1561 tctggtcggc atcgtgctat ggtggtagcc aagctcctgg agaagagaca ggcggagatt
1621 gaggctgagc gttgtggaga atcagaagcc gcagatgaga agggttccat cgcctctggc
1681 tccctttctg ctcccagtgc tcccattttc caggatgtcc tcctgcagtt tctggataca
1741 caggctccca tgctgacgga ccctcgaagt gagagtgagc gggtggaatt ctttaactta
1801 gtactgctgt tctgtgaact gattcgacat gatgttttct cccacaacat gtatacttgc
1861 actctcatct cccgagggga ccttgccttt ggagcccctg gtccccggcc tccctctccc
1921 tttgatgatc ctgccgatga cccagagcac aaggaggctg aaggcagcag cagcagcaag
1981 ctggaagatc cagggctctc agaatctatg gacattgacc ctagttccag tgttctcttt
2041 gaggacatgg agaagcctga tttctcattg ttctccccta ctatgccctg tgaggggaag
2101 ggcagtccat cccctgagaa gccagatgtc gagaaggagg tgaagccccc acccaaggag
2161 aagattgaag ggacccttgg ggttctttac gaccagccac gacacgtgca gtacgccacc
2221 cattttccca tcccccagga ggagtcatgc agccatgagt gcaaccagcg gttggtcgta
2281 ctgtttgggg tgggaaagca gcgagatgat gcccgccatg ccatcaagaa aatcaccaag
2341 gatatcttga aggttctgaa ccgcaaaggg acagcagaaa ctgaccagct tgctcctatt
2401 gtgcctctga atcctggaga cctgacattc ttaggtgggg aggatgggca gaagcggcga
2461 cgcaaccggc ctgaagcctt ccccactgct gaagatatct ttgctaagtt ccagcacctt
2521 tcacattatg accaacacca ggtcacggct caggtctccc ggaatgttct ggagcagatc
2581 acgagctttg cccttggcat gtcataccac ttgcctctgg tgcagcatgt gcagttcatc
2641 ttcgacctca tggaatattc actcagcatc agtggcctca tcgactttgc cattcagctg
2701 ctgaatgaac tgagtgtagt tgaggctgag ctgcttctca aatcctcgga tctggtgggc
2761 agctacacta ctagcctgtg cctgtgcatc gtggctgtcc tgcggcacta tcatgcctgc
2821 ctcatcctca accaggacca gatggcacag gtctttgagg ggctgtgtgg cgtcgtgaag
2881 catgggatga accggtccga tggctcctct gcagagcgct gtatccttgc ttatctctat
2941 gatctgtaca cctcctgtag ccatttaaag aacaaatttg gggagctctt cagcgacttt
3001 tgctcaaagg tgaagaacac catctactgc aacgtggagc catcggaatc aaatatgcgc
3061 tgggcacctg agttcatgat cgacactcta gagaaccctg cagctcacac cttcacctac
3121 acggggctag gcaagagtct tagtgagaac cctgctaacc gctacagctt tgtctgcaat
3181 gcccttatgc acgtctgtgt ggggcaccat gatcccgata gggtgaatga catcgcaatc
3241 ctgtgtgcag agctgaccgg ctattgcaag tcactgagtg cagaatggct aggagtgctt
3301 aaggccttgt gctgctcctc taacaatggc acttgtggtt tcaacgatct cctctgcaat
3361 gttgatgtca gtgacctatc ttttcatgac tcgctggcta cttttgttgc catcctcatc
3421 gctcggcagt gtttgctcct ggaagatctg attcgctgtg ctgccatccc ttcactcctt
3481 aatgctgctt gtagtgaaca ggactctgag ccaggggccc ggcttacctg ccgcatcctc
3541 cttcaccttt tcaagacacc gcagctcaat ccttgccagt ctgatggaaa caagcctaca
3601 gtaggaatcc gctcctcctg cgaccgccac ctgctggctg cctcccagaa ccgcatcgtg
3661 gatggagccg tgtttgctgt tctcaaggct gtgtttgtac ttggggatgc ggaactgaaa
3721 ggttcaggct tcactgtgac aggaggaaca gaagaacttc cagaggagga gggaggaggt
3781 ggcagtggtg gtcggaggca gggtggccgc aacatctctg tggagacagc cagtctggat
3841 gtctatgcca agtacgtgct gcgcagcatc tgccaacagg aatgggtagg agaacgttgc
3901 cttaagtctc tgtgtgagga cagcaatgac ctgcaagacc cagtgttgag tagtgcccag
3961 gcgcagcgcc tcatgcagct catttgctat ccacatcgac tgctggacaa tgaggatggg
4021 gaaaaccccc agcggcagcg cataaagcgc attctccaga acttggacca gtggaccatg
4081 cgccagtctt ccttggagct gcagctcatg atcaagcaga cccctaacaa tgagatgaac
4141 tccctcttgg agaacatcgc caaggccaca atcgaggttt tccaacagtc agcagagaca
4201 gggtcatctt ctggaagtac tgcaagcaac atgcccagca gcagcaagac caagcctgtg
4261 ctcagctctc tagagcgctc tggtgtatgg ctggtggccc ccctcattgc taaactgccc
4321 acctcagtcc agggacatgt gttaaaggct gctggggaag aattggagaa gggtcagcac
4381 ctgggttcct cttcacgcaa agaacgtgat cgacaaaagc agaagagcat gtccctattg
4441 agccagcagc ccttcttatc gctggtgcta acatgtctga aagggcagga tgaacaacgc
4501 gagggactcc ttacctccct ctacagccag gtgcaccaga ttgtgaataa ttggcgagat
4561 gaccagtact tagatgattg caaaccaaag cagcttatgc atgaggcact caaactgcgg
4621 ctcaacctgg tggggggcat gtttgacacg gtgcagcgca gcacccagca gaccacggag
4681 tgggccatgc tcctcctgga gatcatcatc agcggcactg tcgacatgca gtccaacaat
4741 gagctcttca ctactgtgtt ggacatgctg agcgtgctca tcaatgggac attggctgca
4801 gacatgtcta gcatctcgca aggtagcatg gaggaaaaca agcgtgcata catgaacctg
4861 gcgaagaagt tgcagaagga gttgggggag cgccagtcag acagtctgga aaaggttcgc
4921 cagctgctgc cactgcccaa gcagacccga gatgtcatca cgtgtgagcc acagggctcc
4981 cttatcgata ccaagggcaa caagattgct ggcttcgatt ccatcttcaa gaaggagggt
5041 ctacaggttt ccaccaaaca gaagatctcg ccctgggatc tttttgaggg gttgaagccg
5101 tcagcaccac tctcttgggg ctggtttgga acagtccgag tggaccggcg agtggctcga
5161 ggagaggagc agcagcggtt gctgctctac cacacacacc tgaggccccg gccccgcgcc
5221 tattacctgg agccactgcc actgccccca gaagatgagg agccgcctgc tcctaccctg
5281 ctagagcctg agaaaaaggc tccagagccc cccaaaactg acaaaccggg ggctgctcca
5341 cccagtactg aggaacgcaa gaagaagtcc accaagggca agaaacgcag ccagccagct
5401 accaagacag aggactatgg aatgggcccg ggtcggagcg gcccttatgg tgtgacagtg
5461 cctccggacc tcctgcacca cccaaaccct ggttctataa cacaccttaa ctacaggcaa
5521 ggctccatag gcctgtacac ccagaaccag ccactacctg caggtggccc tcgtgtggac
5581 ccataccgtc ctgtgcgctt accaatgcag aagctgccca cccgaccaac ttaccctgga
5641 gtgctgccca caaccatgac tggcgtcatg ggtttagaac cctcctctta taagacctct
5701 gtgtaccggc agcagcaacc tgcggtgccc caaggacagc gccttcgcca acagctccag
5761 agtcagggca tgttgggaca gtcatctgtc catcagatga ctcccagctc ttcctacggt
5821 ttgcagactt cccagggcta tactccttat gtttctcatg tgggattgca gcaacacaca
5881 ggccctgcag gtaccatggt gccccccagc tactccagcc agccttacca gagcacccac
5941 ccttctacca atcctactct tgtagatcct acccgccacc tgcaacagcg gcccagtggc
6001 tatgtgcacc agcaggcccc cacctatgga catggactga cctccactca aaggttttca
6061 caccagacac tgcagcagac acccatgata agtaccatga ctccaatgag tgcccagggc
6121 gtccaggcag gcgtccgttc aacagccatc ctacctgagc agcagcagca gcagcaacag
6181 cagcaacagc aacagcagca gcagcagcaa cagcaacagc agcagcagca gcagcagtac
6241 cacatccggc agcagcagca gcagcagatc ctgcggcagc agcagcaaca gcaacagcag
6301 cagcagcagc agcagcaaca gcaacagcag cagcagcaac agcaacaaca gcaacaccag
6361 cagcaacagc agcaacaggc ggctcctccc caaccccagc cccagtccca gccccagttc
6421 cagcgccagg ggcttcagca gacccagcag cagcaacaga cagcagcttt ggtccggcaa
6481 cttcaacaac agctctctaa tacccagcca cagcccagta ccaacatatt tggacgctac
6541 tgagccacct ggaggaactg cttgtgcact ggatgtggcc ccaccctttc ctcttaattc
6601 ccaatcccat tcctgggcta gcaccagtag tggttggggc cctcccctca ggctccattt
6661 ttaataagtt tttagtattt ttgttaatgt gaggcattga gctgttgggt tttgtatatt
6721 atttatatag agaccccaga gctgttgcac ccaatacaca gagcttcttt gcaaaaaaaa
6781 aaaaaaaa
//