LOCUS AF069987 1385 bp mRNA linear HUM 23-JUL-1998
DEFINITION Homo sapiens nitrilase 1 (NIT1) mRNA, complete cds.
ACCESSION AF069987
VERSION AF069987.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1385)
AUTHORS Pekarsky,Y., Campiglio,M., Siprashvili,Z., Druck,T., Sedkov,Y.,
Tillib,S., Draganescu,A., Wermuth,P., Rothman,J.H., Huebner,K.,
Buchberg,A.M., Mazo,A., Brenner,C. and Croce,C.M.
TITLE Nitrilase and Fhit homologs are encoded as fusion proteins in
Drosophila melanogaster and Caenorhabditis elegans
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (15), 8744-8749 (1998)
PUBMED 9671749
REFERENCE 2 (bases 1 to 1385)
AUTHORS Pekarsky,Y., Campiglio,M., Siprashvili,Z., Druck,T., Sedkov,Y.,
Tillib,S., Draganescu,A., Wermuth,P., Rothman,J., Huebner,K.,
Buchberg,A.M., Mazo,A., Brenner,C. and Croce,C.M.
TITLE Direct Submission
JOURNAL Submitted (04-JUN-1998) Kimmel Cancer Inst., Thomas Jefferson
Univ., 233 S. Tenth St., Philadelphia, PA 19107, USA
FEATURES Location/Qualifiers
source 1..1385
/db_xref="H-InvDB:HIT000065683"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q21-q22"
gene 1..1385
/gene="NIT1"
CDS 77..1060
/gene="NIT1"
/note="Nit1"
/codon_start=1
/product="nitrilase 1"
/protein_id="AAC39907.1"
/translation="MLGFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAMAISSSSC
ELPLVAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLHLS
EPLGGKLLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYR
KTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQA
GAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVD
PWGTVVARCSEGPGLCLARIDLNYLRQLRRHLPVFQHRRPDLYGNLGHPLS"
BASE COUNT 322 a 382 c 357 g 324 t
ORIGIN
1 gcccactcgc tgcggcctat ctggctccag accgccctcc ggatcggacc ctgcgaatgg
61 ttttggctat atcttcatgc tgggcttcat caccaggcct cctcacagat tcctgtccct
121 tctgtgtcct ggactccgga tacctcaact ctcagtactt tgtgctcagc ccaggcccag
181 agccatggct atctcctctt cctcctgcga actgcccctg gtggctgtgt gccaggtaac
241 atcgacgcca gacaagcaac agaactttaa aacatgtgct gagctggttc gagaggctgc
301 cagactgggt gcctgcctgg ctttcctgcc tgaggcattt gacttcattg cacgggaccc
361 tgcagagacg ctacacctgt ctgaaccact gggtgggaaa cttttggaag aatacaccca
421 gcttgccagg gaatgtggac tctggctgtc cttgggtggt ttccatgagc gtggccaaga
481 ctgggagcag actcagaaaa tctacaattg tcacgtgctg ctgaacagca aaggggcagt
541 agtggccact tacaggaaga cacatctgtg tgacgtagag attccagggc aggggcctat
601 gtgtgaaagc aactctacca tgcctgggcc cagtcttgag tcacctgtca gcacaccagc
661 aggcaagatt ggtctagctg tctgctatga catgcggttc cctgaactct ctctggcatt
721 ggctcaagct ggagcagaga tacttaccta tccttcagct tttggatcca ttacaggccc
781 agcccactgg gaggtgttgc tgcgggcccg tgctatcgaa acccagtgct atgtagtggc
841 agcagcacag tgtggacgcc accatgagaa gagagcaagt tatggccaca gcatggtggt
901 agacccctgg ggaacagtgg tggcccgctg ctctgagggg ccaggcctct gccttgcccg
961 aatagacctc aactatctgc gacagttgcg ccgacacctg cctgtgttcc agcaccgcag
1021 gcctgacctc tatggcaatc tgggtcaccc actgtcttaa gacttgactt ctgtgagttt
1081 agacctgccc ctcccacccc caccctgcca ctatgagcta gtgctcatgt gacttggagg
1141 caggatccag gcacagctcc cctcacttgg agaaccttga ctctcttgat ggaacacaga
1201 tgggctgctt gggaaagaaa ctttcacctg agcttcacct gaggtcagac tgcagtttca
1261 gaaaggtgga attttatata gtcattgttt atttcatgga aactgaagtt ctgctgaggg
1321 ctgagcagca ctggcattga aaaatataat aatcataaag tcaaaaaaaa aaaaaaaaaa
1381 aaaaa
//