LOCUS AF069755 3075 bp mRNA linear HUM 07-APR-1999
DEFINITION Homo sapiens orphan G protein-coupled receptor HG20 (HG20) mRNA,
complete cds.
ACCESSION AF069755
VERSION AF069755.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3075)
AUTHORS Ng,G.Y.K., McDonald,T., Bonnert,T., Rigby,M., Heavens,R.,
Whiting,P., Chateauneuf,A., Coulombe,N., Kargmen,S., Caskey,T.,
Evans,J., O'Neill,G.P. and Liu,Q.
TITLE Cloning of a novel G-protein-coupled receptor GPR 51 resembling
GABAB receptors expressed predominantly in nervous tissues and
mapped proximal to the hereditary sensory neuropathy type 1 locus
on chromosome 9
JOURNAL Genomics 56 (3), 288-295 (1999)
PUBMED 10087195
REFERENCE 2 (bases 1 to 3075)
AUTHORS McDonald,T. and Liu,Q.
TITLE Direct Submission
JOURNAL Submitted (03-JUN-1998) Human Genetics, Merck Research Labs, West
Point, PA 19486, USA
FEATURES Location/Qualifiers
source 1..3075
/db_xref="H-InvDB:HIT000065676"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="4.81 cM from WI-8684"
gene 1..3075
/gene="HG20"
CDS 157..2982
/gene="HG20"
/note="member of GABAb receptor family"
/codon_start=1
/product="orphan G protein-coupled receptor HG20"
/protein_id="AAC99345.1"
/translation="MASPRRSGQPGRPPPPPPPPARLLLLLLLPLLLPLAPGAWGWAR
GAPRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLR
LYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATT
PVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGV
LYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSK
YQWIIPGWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKT
PQQYEREYNNKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTD
HTLGRIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLE
IINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRN
QKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTT
AFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRT
VEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVS
IPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVF
VPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRL
RMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILNLGNFTESTDGGKAILKN
HLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASC
VSPCVSPTASPRHRHVPPSFRVMVSGL"
BASE COUNT 729 a 925 c 830 g 591 t
ORIGIN
1 ccgttctgag ccgagccgga accctagccc gagacggagc cggggcccgg gccggcgcca
61 ttgcgcgggc gccgcgggaa gaccttggcg cggggcggcg ggccgggcca ggccatgcgg
121 gccgagtgag ccggcgcccg cagcccgcgg cgcggcatgg cttccccgcg gaggtccggg
181 cagccagggc ggccgccgcc gccgccaccg ccgcccgcgc gcctgctact gctactgctg
241 ctgccgctgc tgctgcctct ggcgcccggg gcctggggct gggcgcgggg cgccccccgg
301 ccgccgccca gcagcccgcc gctctccatc atgggcctca tgccgctcac caaggaggtg
361 gccaagggca gcatcgggcg cggtgtgctc cccgccgtgg aactggccat cgagcagatc
421 cgcaacgagt cactcctgcg cccctacttc ctcgacctgc ggctctatga cacggagtgc
481 gacaacgcaa aagggttgaa agccttctac gatgcaataa aatacgggcc gaaccacttg
541 atggtgtttg gaggcgtctg tccatccgtc acatccatca ttgcagagtc cctccaaggc
601 tggaatctgg tgcagctttc ttttgctgca accacgcctg ttctagccga taagaaaaaa
661 tacccttatt tctttcggac cgtcccatca gacaatgcgg tgaatccagc cattctgaag
721 ttgctcaagc actaccagtg gaagcgcgtg ggcacgctga cgcaagacgt tcagaggttc
781 tctgaggtgc ggaatgacct gactggagtt ctgtatggcg aggacattga gatttcagac
841 accgagagct tctccaacga tccctgtacc agtgtcaaaa agctgaaggg gaatgatgtg
901 cggatcatcc ttggccagtt tgaccagaat atggcagcaa aagtgttctg ttgtgcatac
961 gaggagaaca tgtatggtag taaatatcag tggatcattc cgggctggta cgagccttct
1021 tggtgggagc aggtgcacac ggaagccaac tcatcccgct gcctccggaa gaatctgctt
1081 gctgccatgg agggctacat tggcgtggat ttcgagcccc tgagctccaa gcagatcaag
1141 accatctcag gaaagactcc acagcagtat gagagagagt acaacaacaa gcggtcaggc
1201 gtggggccca gcaagttcca cgggtacgcc tacgatggca tctgggtcat cgccaagaca
1261 ctgcagaggg ccatggagac actgcatgcc agcagccggc accagcggat ccaggacttc
1321 aactacacgg accacacgct gggcaggatc atcctcaatg ccatgaacga gaccaacttc
1381 ttcggggtca cgggtcaagt tgtattccgg aatggggaga gaatggggac cattaaattt
1441 actcaatttc aagacagcag ggaggtgaag gtgggagagt acaacgctgt ggccgacaca
1501 ctggagatca tcaatgacac catcaggttc caaggatccg aaccaccaaa agacaagacc
1561 atcatcctgg agcagctgcg gaagatctcc ctacctctct acagcatcct ctctgccctc
1621 accatcctcg ggatgatcat ggccagtgct tttctcttct tcaacatcaa gaaccggaat
1681 cagaagctca taaagatgtc gagtccatac atgaacaacc ttatcatcct tggagggatg
1741 ctctcctatg cttccatatt tctctttggc cttgatggat cctttgtctc tgaaaagacc
1801 tttgaaacac tttgcaccgt caggacctgg attctcaccg tgggctacac gaccgctttt
1861 ggggccatgt ttgcaaagac ctggagagtc cacgccatct tcaaaaatgt gaaaatgaag
1921 aagaagatca tcaaggacca gaaactgctt gtgatcgtgg ggggcatgct gctgatcgac
1981 ctgtgtatcc tgatctgctg gcaggctgtg gaccccctgc gaaggacagt ggagaagtac
2041 agcatggagc cggacccagc aggacgggat atctccatcc gccctctcct ggagcactgt
2101 gagaacaccc atatgaccat ctggcttggc atcgtctatg cctacaaggg acttctcatg
2161 ttgttcggtt gtttcttagc ttgggagacc cgcaacgtca gcatccccgc actcaacgac
2221 agcaagtaca tcgggatgag tgtctacaac gtggggatca tgtgcatcat cggggccgct
2281 gtctccttcc tgacccggga ccagcccaat gtgcagttct gcatcgtggc tctggtcatc
2341 atcttctgca gcaccatcac cctctgcctg gtattcgtgc cgaagctcat caccctgaga
2401 acaaacccag atgcagcaac gcagaacagg cgattccagt tcactcagaa tcagaagaaa
2461 gaagattcta aaacgtccac ctcggtcacc agtgtgaacc aagccagcac atcccgcctg
2521 gagggcctac agtcagaaaa ccatcgcctg cgaatgaaga tcacagagct ggataaagac
2581 ttggaagagg tcaccatgca gctgcaggac acaccagaaa agaccaccta cattaaacag
2641 aaccactacc aagagctcaa tgacatcctc aacctgggaa acttcactga gagcacagat
2701 ggaggaaagg ccattttaaa aaatcacctc gatcaaaatc cccagctaca gtggaacaca
2761 acagagccct ctcgaacatg caaagatcct atagaagata taaactctcc agaacacatc
2821 cagcgtcggc tgtccctcca gctccccatc ctccaccacg cctacctccc atccatcgga
2881 ggcgtggacg ccagctgtgt cagcccctgc gtcagcccca ccgccagccc ccgccacaga
2941 catgtgccac cctccttccg agtcatggtc tcgggcctgt aagggtgggg ggcctgggcc
3001 cggggcctcc cccgtgacag aaccacactg ggcagagggg tctgctgcag aaacactgtc
3061 ggctctggct gcgga
//