LOCUS AF069604 1745 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens myosin light chain kinase isoform 4 (MLCK) mRNA,
partial cds.
ACCESSION AF069604
VERSION AF069604.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1745)
AUTHORS Lazar,V.L. and Garcia,J.G.N.
TITLE A Single Human MLCK Gene Transcribes Multiple Isoforms
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1745)
AUTHORS Lazar,V.L. and Garcia,J.G.N.
TITLE Direct Submission
JOURNAL Submitted (03-JUN-1998) Medicine, Indiana University, 1481 W. 10th
Street, 111P, Indianapolis, IN 46202, USA
FEATURES Location/Qualifiers
source 1..1745
/db_xref="H-InvDB:HIT000065663"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3qcen-q21"
/cell_line="HUVEC"
/cell_type="endothelial"
/tissue_type="umbilical vein"
gene <1..1745
/gene="MLCK"
CDS <1..1683
/gene="MLCK"
/codon_start=1
/product="myosin light chain kinase isoform 4"
/protein_id="AAD15924.1"
/translation="SEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN
LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA
TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKMKWRCQTD
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSLFERIIDEDFELTERECIKYMRQISE
GVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVA
PEVINYEPIDATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEI
SDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQ
KTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK
PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED
GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEHIVETMEEGEGEGEEEEE"
BASE COUNT 503 a 420 c 480 g 342 t
ORIGIN
1 agcgagcaca tcaaggtgga gaacagcgag aatggcagca agctcaccat cctggccgcg
61 cgccaggagc actgcggctg ctacacactg ctggtggaga acaagctggg cagcaggcag
121 gcccaggtca acctcactgt cgtggataag ccagaccccc cagctggcac accttgtgcc
181 tctgacattc ggagctcctc actgaccctg tcctggtatg gctcctcata tgatgggggc
241 agtgctgtac agtcctacag catcgagatc tgggactcag ccaacaagac gtggaaggaa
301 ctagccacat gccgcagcac ctctttcaac gtccaggacc tgctgcctga ccacgaatat
361 aagttccgtg tacgtgcaat caacgtgtat ggaaccagtg agccaagcca ggagtctgaa
421 ctcacaacgg taggagagaa acctgaagag ccgaagatga agtggaggtg tcagactgat
481 gatgagaagg agcccgaggt tgattaccgg acagtgacaa tcaatactga acaaaaagta
541 tctgacttct acgacattga ggagagatta ggatcgctgt ttgagcgcat cattgacgag
601 gactttgagc tgacggagcg tgagtgcatc aagtacatgc ggcagatctc ggagggagtg
661 gagtacatcc acaagcaggg catcgtgcac ctggacctca agccggagaa catcatgtgt
721 gtcaacaaga cgggcaccag gatcaagctc atcgactttg gtctggccag gaggctggag
781 aatgcggggt ctctgaaggt cctctttggc accccagaat ttgtggctcc tgaagtgatc
841 aactatgagc ccatcgacgc cacagacatg tggagcatcg gggtcatctg ctacatccta
901 gtcagtggcc tttccccctt catgggagac aacgataacg aaaccttggc caacgttacc
961 tcagccacct gggacttcga cgacgaggca ttcgatgaga tctccgacga tgccaaggat
1021 ttcatcagca atctgctgaa gaaagatatg aaaaaccgcc tggactgcac gcagtgcctt
1081 cagcatccat ggctaatgaa agataccaag aacatggagg ccaagaaact ctccaaggac
1141 cggatgaaga agtacatggc aagaaggaaa tggcagaaaa cgggcaatgc tgtgagagcc
1201 attggaagac tgtcctctat ggcaatgatc tcagggctca gtggcaggaa atcctcaaca
1261 gggtcaccaa ccagcccgct caatgcagaa aaactagaat ctgaagaaga tgtgtcccaa
1321 gctttccttg aggctgttgc tgaggaaaag cctcatgtaa aaccctattt ctctaagacc
1381 attcgcgatt tagaagttgt ggagggaagt gctgctagat ttgactgcaa gattgaagga
1441 tacccagacc ccgaggttgt ctggttcaaa gatgaccagt caatcaggga gtcccgccac
1501 ttccagatag actacgatga ggacgggaac tgctctttaa ttattagtga tgtttgcggg
1561 gatgacgatg ccaagtacac ctgcaaggct gtcaacagtc ttggagaagc cacctgcaca
1621 gcagagcaca ttgtggaaac gatggaggaa ggtgaagggg aaggggaaga ggaagaagag
1681 tgaaacaaag ccagagaaaa gcagtttcta agtcatatta aaaggactat ttctctcaaa
1741 atcca
//