LOCUS AF069517 3697 bp mRNA linear HUM 11-JUN-1998
DEFINITION Homo sapiens RNA binding protein DEF-3 mRNA, complete cds.
ACCESSION AF069517
VERSION AF069517.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3697)
AUTHORS Drabkin,H.A., West,J.D., Hotfilder,M., Heng,Y., Erickson,P.,
Calvo,R., Dalmau,J., Gemmill,R.M. and Sablitzky,F.
TITLE DEF-3, an RNA binding protein from the 3p21.3 homozygous deletion
region in SCLC
JOURNAL Oncogene (1998) In press
REFERENCE 2 (bases 1 to 3697)
AUTHORS Drabkin,H.A., West,J.D., Hotfilder,M., Heng,Y., Erickson,P.,
Calvo,R., Dalmau,J., Gemmill,R.M. and Sablitzky,F.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-1998) Medical Oncology, University of Colorado
Health Sciences Center, 4200 E. 9th Ave Box B171, Denver, CO 80262,
USA
FEATURES Location/Qualifiers
source 1..3697
/db_xref="H-InvDB:HIT000065658"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21.3"
/note="homozygous deletion region"
CDS 205..3576
/codon_start=1
/product="RNA binding protein DEF-3"
/protein_id="AAC21578.1"
/translation="MWGDSRPANRTGPFRGSQEERFAPGWNRDYPPPPLKSHAQERHS
GNFPGRDSLPFDFQGHSGPPFANVEEHSFSYGARDGPHGDYRGGEGPGHDFRGGDFSS
SDFQSRDSSQLDFRGRDIHSGDFRDREGPPMDYRGGDGTSMDYRGREAPHMNYRDRDA
HAVDFRGRDAPPSDFRGRGTYDLDFRGRDGSHADFRGRDLSDLDFRAREQSRSDFRNR
DVSDLDFRDKDGTQVDFRGRGSGTTDLDFRDRDTPHSDFRGRHRSRTDQDFRGREMGS
CMEFKDREMPPVDPNILDYIQPSTQDREHSGMNVNRREESTHDHTIERPAFGIQKGEF
EHSETREGETQGVAFEHESPADFQNSQSPVQDQDKSQLSGREEQSSDAGLFKEEGGLD
FLGRQDTDYRSMEYRDVDHRLPGSQMFGYGQSKSFPEGKTARDAQRDLQDQDYRTGPS
EEKPSRLIRLSGVPEDATKEEILNAFRTPDGMPVKNLQLKEYNTGYDYGYVCVEFSLL
EDAIGCMEANQGTLMIQDKEVTLEYVSSLDFWYCKRCKANIGGHRSSCSFCKNPREVT
EAKQELITYPQPQKTSIPAPLEKQPNQPLRPADKEPEPRKREEGQESRLGHQKREAER
YLPPSRREGPTFRRDREKESWSGETRQDGESKTIMLKRIYRSTPPEVIVEVLEPYVRL
TTANVRIIKNRTGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATG
KRRNDSGDHSDHMHYYQGKKYFRDRRGGGRNSDWSSDTNRQGQQSSSDCYIYDSATGY
YYDPLAGTYYDPNTQQEVYVPQDPGLPEEEEIKEKKPTSQGKSSSKKEMSKRDGKEKK
DRGVTRFQENASEGKAPAEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDY
EEEEEEEQTPPPQPRTAQPQKREEQTKKENEEDKLTDWNKLACLLCRRQFPNKEVLIK
HQQLSDLHKQNLEIHRKIKQSEQELAYLERREREGKFKGRGNDRREKLQSFDSPERKR
IKYSRETDSDRKLVDKEDIDTSSKGGCVQQATGWRKGTGLGYGHPGLASSEEAEGRMR
GPSVGASGRTSKRQSNETYRDAVRRVMFARYKELD"
BASE COUNT 1111 a 771 c 1012 g 803 t
ORIGIN
1 cgggagatga aggcagcggc gcggcgcctt tgtggtagca gtggccccgc gcggaggaag
61 ttccggtgtc cgcggcgctg ggtcggtggc ggaggctgag gagaaggagg agcgggccgt
121 ggaggcttcg ccgcctaggt actgctataa ccagaatttg gtagaaaaag gatttacttg
181 ttggggccct cttgataaaa agagatgtgg ggggattctc gacctgctaa cagaactgga
241 ccttttcgtg ggagccaaga agaaaggttt gctcccgggt ggaacaggga ttatcctcct
301 cctcccctta agagtcatgc tcaagagaga cactctggca actttcctgg cagagattca
361 cttccctttg atttccaggg gcattcgggg cctccttttg caaatgtaga ggagcattct
421 ttcagctatg gagctagaga cggaccgcat ggtgactatc gaggagggga gggacctgga
481 catgatttca gggggggaga tttttcgtct tctgatttcc agagcagaga ttcatcacag
541 ttggacttca ggggtaggga catacattct ggggattttc gggatagaga aggaccacct
601 atggactata ggggtggaga tggtacttct atggattata gaggtaggga ggcacctcat
661 atgaactaca gagacaggga tgctcacgct gttgacttca gaggtaggga tgctcctcca
721 tctgacttca ggggccgggg cacttatgat ttagatttta gaggccggga tggatcccat
781 gcagatttta ggggaaggga tttatcagat ttggatttta gggccagaga acagtcccgt
841 tctgatttta ggaatagaga tgtatctgat ttggacttta gagacaaaga cggaacacaa
901 gtagacttta gaggccgagg ttcaggtact actgatctag actttaggga cagggatacg
961 ccacattcag atttcagagg tagacaccga tctaggactg atcaggattt taggggcaga
1021 gagatgggat cttgtatgga atttaaagat agggagatgc cccctgtgga tccaaatatt
1081 ttggattaca ttcagccctc tacacaagat agagaacatt ctggtatgaa tgtgaacagg
1141 agagaagaat ccacacatga ccatacgata gaaaggcctg cttttggcat tcagaaggga
1201 gaatttgagc attcagaaac aagagaagga gaaacacaag gtgtagcctt tgaacatgag
1261 tctccagcag actttcagaa cagccaaagt ccagttcaag accaagataa gtcacagctt
1321 tctggacgtg aagagcagag ttcagatgct ggtctgttta aagaagaagg cggcctggac
1381 tttcttgggc ggcaagacac cgattacaga agcatggagt accgtgatgt ggatcatagg
1441 ctgccaggaa gccagatgtt tggctatggc cagagcaagt cttttccaga gggcaaaact
1501 gcccgagatg cccaacggga ccttcaggat caagattata ggaccggccc aagtgaggag
1561 aaacccagca ggcttattcg attaagtggg gtacctgaag atgccacaaa agaagagatt
1621 cttaatgctt ttcggactcc tgatggcatg cctgtaaaga acttgcagtt gaaggagtat
1681 aacacaggtt acgactatgg ctatgtctgc gtggagtttt cactcttgga agatgccatc
1741 ggatgcatgg aggccaacca gggaactcta atgatccagg acaaagaagt taccctggag
1801 tatgtatcaa gcctggattt ttggtactgc aaacgatgta aggcaaacat tggtgggcac
1861 cgatcttcct gttcattctg caagaaccca agagaagtga cagaggccaa gcaagaatta
1921 ataacctacc ctcagcctca gaaaacatcc ataccagcac cattggaaaa acagcccaac
1981 cagcccctaa gaccagctga taaggaacct gaacccagga agagggaaga aggccaagag
2041 tcacgcttag gacatcaaaa gagagaagca gaaaggtatc tgcctccttc tcgaagggaa
2101 gggccaactt tccgaagaga ccgagagaag gagtcatggt ctggagagac acgccaggat
2161 ggagagagca aaactatcat gctaaagcgt atctatcgtt ccacaccacc tgaggtgata
2221 gtggaagtgc tggagcccta tgtccgcctt actactgcca acgtccgtat catcaagaac
2281 agaacaggcc ctatggggca tacctatggc tttattgacc tcgactccca tgcggaagct
2341 cttcgtgtgg tgaagatctt acagaacctt gatccgccat ttagcattga tgggaagatg
2401 gtagctgtaa acctggccac tggaaaacga agaaatgatt ctggggacca ttctgaccac
2461 atgcattact atcagggtaa aaaatatttc cgagatagga ggggaggtgg cagaaattca
2521 gactggtctt cagatacaaa tcgacaagga caacagtcat catctgactg ctacatatat
2581 gattctgcta ctggctacta ttatgacccc ttggcaggaa cttattatga ccccaatacc
2641 cagcaagaag tctatgtgcc ccaggatcct ggattacctg aggaagaaga gatcaaggaa
2701 aaaaaaccca ccagtcaagg aaagtcaagt agcaagaagg aaatgtctaa aagagatggc
2761 aaggagaaaa aagacagagg agtgacgagg tttcaggaaa atgccagtga agggaaggcc
2821 cctgcagaag acgtctttaa gaagcccctg cctcctactg tgaagaagga agagagtccc
2881 cctccaccta aagtggtaaa cccactgatc ggcctcttgg gtgaatatgg aggagacagt
2941 gactatgagg aggaagaaga ggaggaacag acccctcccc cacagccccg cacagcacag
3001 ccccagaagc gagaggagca aaccaagaag gagaatgaag aagacaaact cactgactgg
3061 aataaactgg cttgtctgct ttgcagaagg cagtttccca ataaagaagt tctgatcaaa
3121 caccagcagc tgtcagacct gcacaagcaa aacctggaaa tccaccggaa gataaaacag
3181 tctgagcagg agctagccta tctggaaagg agagaacgag agggaaagtt taaaggaaga
3241 ggaaatgatc gcagggaaaa gctccagtct tttgactctc cagaaaggaa acggattaag
3301 tactccaggg aaactgacag tgatcgtaaa cttgttgata aagaagatat cgacactagc
3361 agcaaaggag gctgtgtcca acaggctact ggctggagga aagggacagg cctgggatat
3421 ggccatcctg gattggcttc atcagaggag gctgaaggcc ggatgagggg ccccagtgtt
3481 ggagcctcag gaagaaccag caaaagacag tccaacgaga cttaccgaga tgctgttcga
3541 agagtcatgt ttgctcgata taaagaactc gattaagaaa ggagacaagt tccatgggat
3601 acaacctcct tcttgttttg tttgtctctc cttttctttt gttactgttc ttgctgctag
3661 aactttttta aataaacttt ttttcaatgt gaaaaaa
//