LOCUS AF068893 1569 bp mRNA linear HUM 07-JUL-1998
DEFINITION Homo sapiens Duke's type B colon adenocarcinoma suppressin mRNA,
complete cds.
ACCESSION AF068893
VERSION AF068893.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1569)
AUTHORS Manne,U., Grizzle,W.E., Oelschlager,D.K., Gary,B.D., Frost,A.R.,
Weiss,H.L. and LeBoeuf,R.D.
TITLE Altered subcellular localization of suppressin, a novel inhibitor
of cell-cycle entry, is an independent prognostic factor in
colorectal adenocarcinoma
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1569)
AUTHORS LeBoeuf,R.D. and Gary,B.D.
TITLE Direct Submission
JOURNAL Submitted (29-MAY-1998) Physiology, University of Alabama at
Birmingham, 1918 University Blvd, MCLM 850, Birmingham, AL 35209,
USA
FEATURES Location/Qualifiers
source 1..1569
/db_xref="H-InvDB:HIT000065629"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="female"
/cell_line="LS180"
/tissue_type="Duke's type B colon adenocarcinoma"
/dev_stage="58 year old adult"
CDS 25..1518
/function="cell cycle inhibitor"
/codon_start=1
/product="suppressin"
/protein_id="AAC25715.1"
/translation="MAAEPGHMDMGAEALPGPDEAAAAAAFAEVTTVTVANVGAAADN
VFTTSVANAASISGHVLSGRTALQIGDSLNTEKATLIVVHTDGSIVETTGLKGPAAPL
TPGPQSPPTPLAPGQVKGGTNYNWDPSVCDNDLPVRCRNISGTLYKNKLGSGGRGRCI
KQGENWYSPTEFEAMAGRASSKDWKRSIRYAGRPLQCLIQDGILNPHAASCTCAACCD
DMTLSGPVRLFVPYKRRKKENELPTTPVKKDSPKNITLLPATAATTFTVTPSGQITTS
GALTFGQTSTVHATAVISENPAHGDVFAGATVQEASVQPPCRASHPEPHYPGFQDSCQ
IAPFPEAALPTSHPKIVLTSLPALAVPPPTPTKAAPPALANGLELSEPGIWLYLEEMV
NSLLNTAHQLKTLFEQAKHASTYREAATNQAKIHADAKRKEQSCVNCGREAMSECTGC
HKVNYCSNFCQLKDWKDHQHICGHSAVVTVQADEVHVAESVMEKVTV"
BASE COUNT 352 a 509 c 447 g 261 t
ORIGIN
1 ccgcgggtca cagcagtggc ggtgatggcg gcggagcccg ggcacatgga catgggcgcc
61 gaggccctgc ccggccccga cgaggccgcc gctgccgcag ccttcgcaga ggtgaccaca
121 gtgacagtgg ccaacgtggg ggctgctgca gacaatgtct tcaccacgtc tgtggcgaac
181 gcggcatcca tctcaggaca tgttctgtct ggtaggacgg cccttcagat cggggacagc
241 ctgaacaccg aaaaagcgac actgattgtc gtccacacag atgggagcat cgtggagacc
301 accgggctga aaggcccggc agctcccctc accccaggtc ctcagtctcc tccaacccct
361 ctggctcccg gccaagttaa aggtggaact aattacaact gggacccttc tgtgtgtgac
421 aatgacctgc ccgtacggtg ccggaacatc agcggcactc tgtacaagaa caagctcggc
481 tcaggcggcc ggggacggtg catcaagcag ggggagaact ggtacagtcc caccgagttt
541 gaggccatgg caggaagagc cagcagtaag gactggaaaa gaagcattcg ctacgcgggc
601 cgacccttgc agtgcctcat ccaggatggg atcttaaacc ctcacgctgc ctcttgcacc
661 tgtgctgcct gctgcgacga catgacctta agtggcccag tcaggctttt tgtgccttac
721 aaaaggcgca agaaggagaa tgaactgccc acaactcccg tgaagaagga ctcccccaag
781 aacatcacat tgcttccagc caccgcggct accaccttca ccgtgacccc ctcgggacag
841 atcacgacct cgggggcact gacctttggc caaacgtcca cggtacacgc caccgctgtc
901 atatcagaga atccggccca cggcgacgtc ttcgcagggg ccacagtcca agaggccagc
961 gtgcagcccc catgcagggc cagccaccct gagcctcact accccggctt tcaggacagc
1021 tgccagatcg caccgtttcc agaagctgcg ttgccaacgt cacatcccaa aatagtgttg
1081 acatccctgc ctgcgctggc ggtcccaccc ccgactccca ccaaagcggc tcctcccgcg
1141 ttggccaatg ggctggagct gtcagagccg gggatctggc tgtacctaga agagatggtc
1201 aactccttgc tcaacacagc tcatcagctg aagacgctgt ttgagcaagc caagcatgcc
1261 agcacctacc gagaagctgc cacaaaccag gccaagatcc acgctgacgc aaagcggaag
1321 gagcagtcct gcgttaactg cggccgggag gctatgagcg agtgcaccgg ttgccacaag
1381 gtcaactact gctccaactt ctgccaactc aaggactgga aggatcacca gcacatatgc
1441 ggccattcag cagttgtcac cgtccaggca gacgaagtcc acgtggctga aagcgtgatg
1501 gagaaggtga ccgtgtgagg ctccatcggc cgccctggga gcttggggcc cctcgcactc
1561 ctgtgaggc
//