LOCUS AF068864 1635 bp mRNA linear HUM 18-SEP-1998
DEFINITION Homo sapiens p21-activated kinase 3 (PAK3) mRNA, complete cds.
ACCESSION AF068864
VERSION AF068864.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1635)
AUTHORS Allen,K.M., Gleeson,J.G., Bagrodia,S., Partington,M.W.,
MacMillan,J.C., Cerione,R.A., Mulley,J.C. and Walsh,C.A.
TITLE PAK3 mutation in nonsyndromic X-linked mental retardation
JOURNAL Nat. Genet. 20 (1), 25-30 (1998)
PUBMED 9731525
REFERENCE 2 (bases 1 to 1635)
AUTHORS Allen,K.M., Gleeson,J.G. and Walsh,C.A.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-1998) Neurology, Beth Israel Deaconess Medical
Center, HIM845 77 Avenue Louis Pasteur, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..1635
/db_xref="H-InvDB:HIT000065626"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq22-q23"
gene 1..1635
/gene="PAK3"
CDS 1..1635
/gene="PAK3"
/function="serine/threonine kinase"
/codon_start=1
/product="p21-activated kinase 3"
/protein_id="AAC36097.1"
/translation="MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNK
KARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLL
QTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKT
ASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNK
EVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQ
GASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLV
GDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDN
ILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGI
MAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRG
SAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR"
BASE COUNT 535 a 347 c 375 g 378 t
ORIGIN
1 atgtctgacg gtctggataa tgaagagaaa cccccggctc ctccactgag gatgaatagt
61 aacaaccggg attcttcagc actcaaccac agctccaaac cacttcccat ggcccctgaa
121 gagaagaata agaaagccag gcttcgctct atcttcccag gaggagggga taaaaccaat
181 aagaagaagg agaaagagcg cccagagatc tctcttcctt cagactttga gcatacgatt
241 catgtggggt ttgatgcagt caccggggaa ttcactggaa ttccagagca atgggcacga
301 ttactccaaa cttccaacat aacaaaattg gaacagaaga agaacccaca agctgttcta
361 gatgttctca aattctatga ttccaaagaa acagtcaaca accagaaata catgagcttt
421 acatcaggag ataaaagtgc acatggatac atagcagccc atccttcgag tacaaaaaca
481 gcatctgagc ctccattggc ccctcctgtg tctgaagaag aagatgaaga ggaagaagaa
541 gaagaagatg aaaatgagcc accaccagtt atcgcaccaa gaccagagca tacaaaatca
601 atctatactc gttctgtggt tgaatccatt gcttcaccag cagtaccaaa taaagaggtc
661 acaccaccct ctgctgaaaa tgccaattcc agtactttgt acaggaacac agatcggcaa
721 agaaaaaaat ccaagatgac agatgaggag atcttagaga agctaagaag cattgtgagt
781 gttggggacc caaagaaaaa atacacaaga tttgaaaaaa ttggtcaagg ggcatcaggt
841 actgtttata cagcactaga cattgcaaca ggacaagagg tggccataaa gcagatgaac
901 cttcaacagc aacccaagaa ggaattaatt attaatgaaa ttctggtcat gagggaaaat
961 aagaacccta atattgttaa ttatttagat agctacttgg tgggtgatga actatgggta
1021 gtcatggaat acttggctgg tggctctctg actgatgtgg tcacagagac ctgtatggat
1081 gaaggacaga tagcagctgt ctgcagagag tgcctgcaag ctttggattt cctgcactca
1141 aaccaggtga tccatagaga tataaagagt gacaatattc ttctcgggat ggatggctct
1201 gttaaattga ctgactttgg gttctgtgcc cagatcactc ctgagcaaag taaacgaagc
1261 actatggtgg gaaccccata ttggatggca cctgaggtgg tgactcgaaa agcttatggt
1321 ccgaaagttg atatctggtc tcttggaatt atggcaattg aaatggtgga aggtgaaccc
1381 ccttacctta atgaaaatcc actcagggca ttgtatctga tagccactaa tggaactcca
1441 gagctccaga atcctgagag actgtcagct gtattccgtg actttttaaa tcgctgtctt
1501 gagatggatg tggataggcg aggatctgcc aaggagcttt tgcagcatcc atttttaaaa
1561 ttagccaagc ctctctccag cctgactcct ctgattatcg ctgcaaagga agcaattaag
1621 aacagcagcc gctaa
//