LOCUS AF064084 3597 bp mRNA linear HUM 18-MAY-1998
DEFINITION Homo sapiens prenylcysteine carboxyl methyltransferase (PCCMT)
mRNA, complete cds.
ACCESSION AF064084
VERSION AF064084.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3597)
AUTHORS Dai,Q., Choy,E., Chiu,V., Romano,J., Slivka,S.R., Steitz,S.A.,
Michaelis,S. and Philips,M.R.
TITLE Mammalian prenylcysteine carboxyl methyltransferase is in the
endoplasmic reticulum
JOURNAL J. Biol. Chem. 273 (24), 15030-15034 (1998)
PUBMED 9614111
REFERENCE 2 (bases 1 to 3597)
AUTHORS Philips,M.R., Dai,Q., Choy,E. and Chiu,V.
TITLE Direct Submission
JOURNAL Submitted (07-MAY-1998) Medicine & Cell Biology, NYU School of
Medicine, 550 First Avenue, New York, NY 10016, USA
FEATURES Location/Qualifiers
source 1..3597
/db_xref="H-InvDB:HIT000065387"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HL60"
/cell_type="promyelocytic leukemia cell"
gene 1..3597
/gene="PCCMT"
CDS 44..898
/gene="PCCMT"
/note="protein carboxyl methyltransferase; third of three
enzymes that sequentially modify proteins ending with a
CAAX motif such as p21ras and the gamma subunit of G
proteins; similar to Saccharomyces cerevisiae STE14"
/codon_start=1
/product="prenylcysteine carboxyl methyltransferase"
/protein_id="AAC16554.1"
/translation="MAGCAARAPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGL
ALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGTLLSFSQSSWSHFGWYMCSLSL
FHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLS
VTGLLMVVFGECLRKAAMFTAGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFY
WSIGTQVMLCNPICGVSYALTVWRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPF
IKGVKVDL"
BASE COUNT 876 a 873 c 880 g 968 t
ORIGIN
1 ggcacgagcg gcgccgccgc ccgctagtcc gccgcccggc gccatggcgg gctgcgcggc
61 gcgggctccg ccgggctctg aggcgcgtct cagcctcgcc accttcctgc tgggcgcctc
121 ggtgctcgcg ctgccgctgc tcacgcgcgc cggcctgcag ggccgcaccg ggctggcgct
181 ctacgtggcc gggctcaacg cgctgctgct gctgctctat cggccgcctc gctaccagat
241 agccatccga gcttgtttcc tggggtttgt gttcggctgc ggcacgctgc taagttttag
301 ccagtcttct tggagtcact ttggctggta catgtgctcc ctgtcattgt tccactattc
361 tgaatacttg gtgacagcag tcaataatcc caaaagtctg tccttggatt cctttctcct
421 gaatcacagc ctggagtata cagtagctgc tctttcttct tggttagagt tcacacttga
481 aaatatcttt tggccagaac tgaagcagat tacctggctc agtgtcacag ggctgctgat
541 ggtggtcttc ggagaatgtc tgaggaaggc ggccatgttt acagctggct ccaatttcaa
601 ccacgtggta cagaatgaaa aatcagatac acatactctg gtgaccagtg gagtgtacgc
661 ttggtttcgg catccttctt acgtcgggtg gttttactgg agtattggaa ctcaggtgat
721 gctgtgtaac cccatctgcg gcgtcagcta tgccctgaca gtgtggcgat tcttccgcga
781 tcgaacagaa gaagaagaaa tctcactaat tcactttttt ggagaggagt acctggagta
841 taagaagagg gtgcccacgg gcctgccttt cataaagggg gtcaaggtgg acctgtgacg
901 ggcagtggcc ccggtgacct tggggcctcc gaccctgtgc agcctgggac aaaactgttt
961 ccggttggcc gctgccacat ggattttctt aatcgtttta tgtcattagt cactcttctg
1021 gaatgtcact caagaccaag cggtcagaag gcctgaggac ccaaggcccc actggagcag
1081 tctgtcctta tgccgaatca aggcggaaca tgggtgaaag acgagtaagg ggcaaatcac
1141 agcaatattc cacagcgccc tccagagtta cctggggagg accgaggcca cacgccactg
1201 cccccgaggc cagagtgtaa gtaaaggata accaggactc gctgggagag atggactctg
1261 tcctcagcaa cactccacag cagaaagggg tagcaggtac cccttcttat cagcggtaaa
1321 aatgcattta caacctttca tttaaccgaa aaacacagac cgctttaacc tctttatttc
1381 tgtcccccac tgcatgaaca tctatacaat tttaaaaata cttcctcata ggatgctttg
1441 gcccttcatc tatttaatca tagctacata cctatttttt tataagtagc agtacacatt
1501 caaaggggta ttcctagctc aatgcttggt gttctagttc aacttttatc ctgcagcaag
1561 taagcctaga taactctaca cgatttggct gagtggcttt gtgtgaccgt ggccccaggc
1621 caaggggacc atggccctgg ctggctttcc cccgggggtc tcagctcctg ttgtcagtga
1681 taggcggctc aaaggagcat cagtttcttt tgatccaaga agtgcttact gaatgcctgc
1741 cctgtgcgtg gccttaaaca ttgagaagtg ctgctctccg tttatttggg atttgattct
1801 cattttacca tagcttatat tctcaatttc aatgccagtc tcagaactct tgttttctgt
1861 gttctgttct caaaattaca ttgtccctca tgtcatttca aactgttttc caaagggatt
1921 tgagcatata caactacaaa tccaagcaga ttgactctca aaaataatct taaatactgc
1981 aaatagtccc aactaagatt cagtcagtat gtttgttttg caagtttggg agagtaagtt
2041 ggctttgagt cacacatcga agctttaaga ggtgagacgc tggcttcatt ctggactaga
2101 caggaacttg gcctcagcgt gagatcctgc catgcagtgt tgcggtggca ctgaagaagt
2161 gtgaatgtga aggcggcgtc ggcgcggggc cagagcacca ctctgctgcc ccaccacgcg
2221 gcctgtgagg agccactaaa cctttccgtg cctagacctc cccatctgtg gaatggggtc
2281 aataccacct acctcacagg ggtgttgtga ggactgagaa gaacaatgtc aaatgttttt
2341 aatactcaga tgtgggagcg acatcaatga aatctgtact gtatgaaagc tacacaaaaa
2401 tgggcagaca tttggttaat tgtgccagat acctaaaatg tatgttcaga aaagcatttt
2461 atcaactcag aaatatgact tatttctaga ttcatggctt aatgaatttt ttcattgtta
2521 tatataccaa agaggcttac gggttcattg attggtttga aaaccagaca gacggccggg
2581 cacgcctgta atcccaaagt gctgggattg cagcgtgagc caccacgccc agccaagatg
2641 aactccttaa ggacaggatt tggtaagtga ttgacttctt tttagttcca tgatcttgag
2701 attattttta gctttataaa tttagcagtg gcagggcccg tggagaatca ggttaatgag
2761 gtaaaggctt tctgggtatt tgctgccaag gccacatcac caattttctc gatttaaaaa
2821 actgtcaaga gatttatttt tccattgcag gttttaaagt ggagattctg aagtggaaaa
2881 taggtactgt cagaacaaag ctacctggaa acagcataga gtgaagcctt tcgtgagggc
2941 ttgcaggccg ctgctgagtg gcagtttaca gaagaggtcg cggggtgagc ctcttagcag
3001 gacagaaaac aaggcagcag cgcacctgcc accccttcac gagctgctcc ttgagcctaa
3061 aaagtaggct ttattcatcc cttctgttca tttaccaacc tgggggattg atacgaccgg
3121 ggaaaatgtt cctaaaccag gaagctgcgt tagccgatca ggctttgtaa gatctcgcca
3181 acagctagct gcttaggagt acccccacga tacgcacagc acaccactgt cccttcactg
3241 cactttcttc ctgccttagg tagttgggct tgcccaccct agtttgcttt tgtagtggtt
3301 tggcaaggtt agaaggcctc ggcctctctg tcatgctggg aagtgcctac tctctgggcc
3361 actgctgcag aggccgtggc acttgtcatg ggtttggaag acccagccat ctgcagcaga
3421 ggcagcctat cccattgcaa ggagaggaac tgaacggagt aattattcta ctcttctttt
3481 tacataaatg tttatttaaa tattctaaat tggattttca ttcacagata ctgattattc
3541 tttccagttc ttaaataaaa ctgcacttga tttcactcaa aaaaaaaaaa aaaaaaa
//