LOCUS AF061940 3142 bp mRNA linear HUM 04-MAR-1999
DEFINITION Homo sapiens staufen protein (STAU) mRNA, alternatively spliced,
complete cds.
ACCESSION AF061940
VERSION AF061940.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3142)
AUTHORS Wickham,L., Duchaine,T., Luo,M., Nabi,I.R. and DesGroseillers,L.
TITLE Mammalian staufen is a double-stranded-RNA- and tubulin-binding
protein which localizes to the rough endoplasmic reticulum
JOURNAL Mol. Cell. Biol. 19 (3), 2220-2230 (1999)
PUBMED 10022909
REFERENCE 2 (bases 1 to 3142)
AUTHORS DesGroseillers,L., Wickham,L. and Luo,M.
TITLE Direct Submission
JOURNAL Submitted (29-APR-1998) Biochemistry, University of Montreal, 2900
Edouard Montpetit, Montreal, Quebec H3T 1J4, Canada
FEATURES Location/Qualifiers
source 1..3142
/db_xref="H-InvDB:HIT000064991"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20q13.1"
gene 1..3142
/gene="STAU"
CDS 288..1778
/gene="STAU"
/function="RNA binding protein"
/note="alternatively spliced transcript"
/codon_start=1
/product="staufen protein"
/protein_id="AAD17532.1"
/translation="MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPL
LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNK
SEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA
AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKK
EKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVP
QRQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPA
GILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILK
NNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLIS
HGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC"
BASE COUNT 862 a 778 c 733 g 769 t
ORIGIN
1 acttcctgcc gggctgcggg cgcctgagcg ctcttcagcg tttgcgcggc ggctgcgcgt
61 ctctctcggc tcccgcttcc tttgaccgcc tccccccccc ggcccggcgg cgcccgcctc
121 ctccacggcc actccgcctc ttccctccct tcgtcccttc ttcctctccc ttttttcctt
181 cttccttccc ctcctcgccg ccaccgccca ggaccgccgg ccgggggacg agtccggagc
241 agcagccaga aagcataacc cctactgtag aactaaatgc actgtgcatg aaacttggaa
301 aaaaaccaat gtataagcct gttgaccctt actctcggat gcagtccacc tataactaca
361 acatgagagg aggtgcttat cccccgaggt acttttaccc atttccagtt ccacctttac
421 tttatcaagt ggaactttct gtgggaggac agcaatttaa tggcaaagga aagacaagac
481 aggctgcgaa acacgatgct gctgccaaag cgttgaggat cctgcagaat gagcccctgc
541 cagagaggct ggaggtgaat ggaagagaat ccgaagaaga aaatctcaat aaatctgaaa
601 taagtcaagt gtttgagatt gcacttaaac ggaacttgcc tgtgaatttc gaggtggccc
661 gggagagtgg cccaccccac atgaagaact ttgtgaccaa ggtttcggtt ggggagtttg
721 tgggggaagg tgaagggaaa agcaagaaga tttcaaagaa aaatgccgcc atagctgttc
781 ttgaggagct gaagaagtta ccgcccctgc ctgcagttga acgagtaaag cctagaatca
841 aaaagaaaac aaaacccata gtcaagccac agacaagccc agaatatggc caggggatca
901 atccgattag ccgactggcc cagatccagc aggcaaaaaa ggagaaggag ccagagtaca
961 cgctcctcac agagcgaggc ctcccgcgcc gcagggagtt tgtgatgcag gtgaaggttg
1021 gaaaccacac tgcagaagga acgggcacca acaagaaggt ggccaagcgc aatgcagccg
1081 agaacatgct ggagatcctt ggtttcaaag tcccgcagcg gcagcccacc aaacccgcac
1141 tcaagtcaga ggagaagaca cccataaaga aaccagggga tggaagaaaa gtaacctttt
1201 ttgaacctgg ctctggggat gaaaatggga ctagtaataa agaggatgag ttcaggatgc
1261 cttatctaag tcatcagcag ctgcctgctg gaattcttcc catggtgccc gaggtcgccc
1321 aggctgtagg agttagtcaa ggacatcaca ccaaagattt taccagggca gctccgaatc
1381 ctgccaaggc cacggtaact gccatgatag cccgagagtt gttgtatggg ggcacctcgc
1441 ccacagccga gaccatttta aagaataaca tctcttcagg ccacgtaccc catggacctc
1501 tcacgagacc ctctgagcaa ctggactatc tttccagagt ccagggattc caggttgaat
1561 acaaagactt ccccaaaaac aacaagaacg aatttgtatc tcttatcaat tgctcctctc
1621 agccacctct gatcagccat ggtatcggca aggatgtgga gtcctgccat gatatggctg
1681 cgctgaacat cttaaagttg ctgtctgagt tggaccaaca aagtacagag atgccaagaa
1741 caggaaacgg accaatgtct gtgtgtggga ggtgctgaac cttttctggc catgaaccat
1801 tataaaatcc caacatatat actgaaaata ctgaaactgc tttgaaaatt tggaatttct
1861 gatacctcca gtgggccgag agacacggtg ggtaaaggat gtgggcagca gcagggaaga
1921 caacagaaac acaaggaggc ggctgtggcc ggctggactg tgctggggtt tgttgtgatg
1981 gccactcggt gacctggcgg tccctacgca atagcagctg cctgtgggga agaagggctg
2041 cccagccagc tggttctccc gggacaccag cagatccaca ccctgggcac ctccgtgttt
2101 ggtctttttt ttcccctgtg tgaaagaaga aacggcacga ccccttctca agctggctca
2161 ctcagacaca ttgggacaaa ccctggacag ccatgccaga gagaggcctt tgaccggccc
2221 cagagctaaa agcaccagag aaaatcaaat gcttcctact cagcgtgacc caacttttct
2281 agtgtgccac ggccccacca cctcctgcag tacccacacc atcaccactg ctttctcttc
2341 caacagtgat ctgtattctt agtttcatta ttttcttttg attgatatga cactatataa
2401 aattttcatt tgagaatttc tcaattgtat ctagttaaat agcacagttt ggaaacttgt
2461 ctgagactga ctttatcaat aatctaaccg acaaagatca tatccatgtg tatgtggtta
2521 gacattttta tttcattgac taacccagga cagtttcagt gatgcaaatt gtgtgccctc
2581 tggttcagct gaaacagtcc tggactttca aaaaccttga ataagtctcc cacagttgta
2641 taaattggac aatttaggaa ttttaaactt tagatgatca tttggttcca tttttatttc
2701 atttttattt ttgttaatgc aaacaggact taaatgaact ttgatctctg ttttaaagat
2761 tattaaaaaa cattgtgtat ctatacatat ggctcttgag gacttagctt tcactacact
2821 acaggatatg atctccatgt agtccatata aacctgcaga gtgattttcc agagtgctcg
2881 atactgttaa ttacatctcc attagggctg aaaagaatga cctacgtttc tgtatacagc
2941 tgtgttgctt ttgatgttgt gttactgtac acagaagtgt gtgcactgag gctctgcgtg
3001 tggtccgtat ggaaaacctg gtagccctgc gagttaagta ctgcttccat tcattgttta
3061 cgctggaatt tttctcccca tggaatgtaa gtaaaactta agtgtttgtc atcaataaat
3121 ggtaatacta aaaaaaaaaa aa
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