LOCUS AF061243 3432 bp mRNA linear HUM 16-JUL-1999
DEFINITION Homo sapiens metalloprotease 1 (MP1) mRNA, complete cds.
ACCESSION AF061243
VERSION AF061243.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3432)
AUTHORS Mzhavia,N., Berman,Y.L., Qian,Y., Yan,L. and Devi,L.A.
TITLE Cloning, expression, and characterization of human metalloprotease
1: a novel member of the pitrilysin family of metalloendoproteases
JOURNAL DNA Cell Biol. 18 (5), 369-380 (1999)
PUBMED 10360838
REFERENCE 2 (bases 1 to 3432)
AUTHORS Mzhavia,N. and Devi,L.
TITLE Direct Submission
JOURNAL Submitted (22-APR-1998) Pharmacology, NYU Medical Centre, 550 First
Avenue, New York, NY 10016, USA
FEATURES Location/Qualifiers
source 1..3432
/db_xref="H-InvDB:HIT000064958"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3432
/gene="MP1"
CDS 14..3130
/gene="MP1"
/note="metalloendoprotease"
/codon_start=1
/product="metalloprotease 1"
/protein_id="AAC67244.1"
/translation="MWRCGGRQGLCVLRRLSGGHAHHRAWRWNSNRACERALQYKLGD
KIHGFTVNQVTSVPELFLTAVKLTHDDTGARYLHLAREDTNNLFSVQFRTTPMDSTGV
PHILEHTVLCGSQKYPCRNPFFKMLNRSLSTFMNAFTASDYTLYPFSTQNPKDFQNLL
SVYLDATFSPCLRELDFWQEGWRLEHENPSDPQTPLVFKGVVFNEMKGAFTDNERIFS
QHLQNRLLPDHTYSVVSGGDPLCIPELTWEQLKQFHATHYHPSNARFFTYGNFPLEQH
LKQIHEEALSKFQKIEPSTVVPAQTPWDKPREFQITCGPDSFATDPSKQTTVSVSFLL
PDITDTFEAFTLSLLSSLLTSGPNSPFYKALIESGLGTEFSPDVGYNGYTREAYFSVG
LQGIVEKDIETVRSLIDRTIDEVVETRIEDDRIEALLHKIEIQMKHQSTSFGLMLTSY
IASCWNHDGDPVELLKLGNQLAKFRQCLQENPKFLQEKVKQYFKNNQHKLTLSMRPDD
KYHEKQAQVEATKLKQKVEALSPGDRQQIYEKGLELRSQQSKPQDASCLPALKVSDIE
PTIPVTELDVVLTAGDIPVQYCAQPTNGMVYFRAFSSLNTLPEELRPYVPLFCSILTK
LGCGLLDYREQAQQIELKTGGMSASPHVLPDDSHMDTYEQVGVLFSSLCLDRNLPDMM
QLWSEIFNNPCFEEEEHFKVLVKMTAQELANGIPDSGHLYASIRAGRTLTPAGDLQET
FSGMDQVRLMKRIAEMTDIKPILRKLPRIKKHLLNGDNMRCSVNATPQQMPQTEKAVE
DFLRSIGRSKKERRPVRPHTVEKPVPSSSGGDAHVPHGSQVIRKLVMEPTFKPWQMKT
HFLMPFPVNYVGECIRTVPYTDPDHASLKILARLMTAKFLHTEIREKGGAYGGXAKLS
HNGIFTLYSYRDPNTIETLQSFGKAVDWAKSGKFTQQDIDEAKLSVFSTVDAPVAPSD
KGMDHFLYGLSDEMKQAHREQLFAVSHDKLLAVSDRYLGTGKSTHGLAILGPENPKIA
KDPSWIIR"
BASE COUNT 931 a 887 c 835 g 778 t
ORIGIN
1 ctcgtcatgc gcaatgtggc gctgcggcgg gcggcagggc ctgtgtgtgc tgaggcggct
61 gagcggcgga catgcacacc acagagcgtg gcgatggaac agtaaccggg cttgtgagag
121 ggctctgcag tataaactag gagacaagat ccatggattc accgtaaacc aggtgacatc
181 tgttcccgag ctgttcctga ctgcagtgaa gctcacccat gatgacacag gagccaggta
241 tttacacctg gccagagaag acacgaataa tctgttcagc gtgcagttcc gtaccactcc
301 catggacagt actggtgttc ctcacattct tgagcatacc gtcctttgtg ggtctcaaaa
361 atatccgtgc agaaaccctt tcttcaaaat gttgaaccgg tccctctcca cgttcatgaa
421 cgccttcaca gctagtgatt atactctgta tccattttcc acacaaaatc ccaaggactt
481 tcagaatctc ctctcggtgt atttggatgc caccttttcc ccatgtttac gcgagctgga
541 tttctggcag gaaggatggc ggctggaaca tgagaatccg agcgaccccc agacgccctt
601 ggtctttaaa ggagtcgtct ttaatgagat gaagggagcg tttacagaca atgagaggat
661 attctcccag caccttcaga acagacttct tcccgaccac acgtactcag tggtctccgg
721 gggtgaccca ctgtgcatcc cggagcttac atgggagcag cttaagcagt ttcatgccac
781 tcactatcac ccaagcaatg ctaggttctt cacgtacggt aattttccat tagaacagca
841 tctgaaacaa attcacgagg aagcactgag caaattccag aaaattgaac caagcaccgt
901 ggtgccagct cagacaccct gggacaagcc tagggaattc cagataacat gtggcccgga
961 ttcatttgct acagatccct ctaaacaaac aaccgtcagc gttagcttcc tcttaccgga
1021 catcaccgac acatttgaag ccttcacatt aagtcttctg tcttcactct tgacttctgg
1081 gcccaattct cccttttaca aagccttgat tgaatctggc cttggcacag aattttctcc
1141 tgatgttgga tataatggct acacgaggga ggcctacttt agtgtcggcc tccaagggat
1201 tgtggagaaa gacattgaga ccgtcagaag cctcatagac agaacgattg atgaagtagt
1261 tgagacaagg attgaagatg atcgaattga ggctttactt cataaaattg aaatacagat
1321 gaaacatcag tctaccagct ttgggctgat gctgacatca tacatagctt cttgctggaa
1381 ccatgatggg gaccctgtgg agctcttgaa gttgggaaat cagttagcta aattcagaca
1441 gtgcctgcag gaaaatccaa aatttttgca agaaaaagta aaacagtatt ttaagaataa
1501 ccagcataag ctgactttat cgatgaggcc agatgacaag tatcacgaga agcaggcaca
1561 ggtggaagcc acgaagctca agcagaaggt cgaggctctg tcccccggag acaggcagca
1621 gatctacgag aaaggtctag aattacggag tcaacaaagc aaacctcaag atgcctcttg
1681 tctgccagcg ttgaaagttt ccgatattga acccaccata cctgtcacag agttggacgt
1741 ggtcctgaca gctggagata tccctgttca gtactgcgcc cagcccacca atggcatggt
1801 gtatttccgg gccttctcca gcctgaacac actccccgag gagctgaggc cctatgtgcc
1861 cctcttctgc agcatcctca ccaagctggg ctgcggcctt cttgactacc gggagcaggc
1921 tcagcagata gaattgaaga ccggagggat gagtgcttct ccccacgtgc tccccgacga
1981 ctcacacatg gacacctacg agcaggtagg tgtgcttttc tcctctctct gcctggatcg
2041 aaacctgcca gacatgatgc agctatggag tgaaatattt aacaacccgt gctttgaaga
2101 agaggagcac ttcaaggtgc tggtgaagat gaccgcccag gagctcgcca atggaattcc
2161 tgactctggg cacctgtacg catccatcag ggcaggccgg accctcacgc ccgcagggga
2221 cctgcaggag accttcagcg ggatggatca ggtgcggctg atgaagagga ttgcagaaat
2281 gacagatatc aaacccatcc tgaggaagct cccgcgtatc aagaaacact tgttaaatgg
2341 tgataatatg aggtgttcag tgaatgcgac tcctcagcag atgcctcaga cagaaaaagc
2401 ggtcgaagac ttccttagaa gcatcggtcg gagtaaaaag gaacggaggc ctgtgcgccc
2461 acacacggtc gagaaacctg tgcccagcag ctctggtgga gatgcccacg ttccccatgg
2521 ctcccaggtc attaggaagc tggtcatgga acccaccttc aagccctggc agatgaagac
2581 tcacttcctg atgcccttcc cggtgaatta cgtgggtgaa tgcatccgaa ctgtccccta
2641 cacggaccca gatcatgcca gtcttaaaat ccttgcacgt ttgatgactg ccaaattctt
2701 gcatacagaa attcgagaaa aaggcggtgc ttatggtgga ngcgcaaaac tcagccacaa
2761 tgggattttc accctttact cttacaggga cccaaataca atagagacgc tccagtcttt
2821 tgggaaggct gtcgactggg ctaagtctgg aaaattcaca cagcaagaca tcgacgaagc
2881 caaactttct gtcttctcaa ccgtagatgc tcctgtcgct ccttcagaca aaggaatgga
2941 ccacttcttg tacggcctct cggatgagat gaagcaggcc cacagagagc agctctttgc
3001 tgtcagccac gacaagctcc tggccgtgag cgataggtac ctcggcactg ggaagagcac
3061 acacggcctg gccatcctcg gacccgagaa cccgaaaatt gccaaggacc catcctggat
3121 catccgatga gcagccgtgg cgctcgactg cacaggagcc cgagacaata cacctccaag
3181 ctgaatatga aaagtcagaa atgctactgc tttttccaag aatattatgt cattgagtgt
3241 cgccaaagcc cttgactggc gagtcaaaaa ctcagatcta tcttaagagt gaccaggaag
3301 aggttcattg aaataatcat gcatgaagcg ccaaagatgc accatgtaga attttcactt
3361 tgtactggca ggctcgtttt acctgattct agaatattta agaatctaaa aataaagggc
3421 aactctgact ta
//