LOCUS AF057039 2090 bp mRNA linear HUM 17-MAY-2000
DEFINITION Homo sapiens putative renal organic anion transporter 1 (hROAT1)
mRNA, complete cds.
ACCESSION AF057039
VERSION AF057039.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2090)
AUTHORS Reid,G., Wolff,N.A., Dautzenberg,F.M. and Burckhardt,G.
TITLE Cloning of a human renal p-aminohippurate transporter, hROAT1
JOURNAL Kidney Blood Press. Res. 21 (2-4), 233-237 (1998)
PUBMED 9762842
REFERENCE 2 (bases 1 to 2090)
AUTHORS Reid,G., Dautzenberg,F.D., Burckhardt,G. and Wolff,N.A.
TITLE Direct Submission
JOURNAL Submitted (02-APR-1998) Physiologie I, Universitaet Goettingen,
Humboldtallee 23, Goettingen 37073, Germany
REFERENCE 3 (bases 1 to 2090)
AUTHORS Reid,G., Dautzenberg,F.D., Burckhardt,G. and Wolff,N.A.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2000) Physiologie I, Universitaet Goettingen,
Humboldtallee 23, Goettingen 37073, Germany
REMARK Sequence update by submitter
COMMENT On May 17, 2000 this sequence version replaced AF057039.1.
FEATURES Location/Qualifiers
source 1..2090
/db_xref="H-InvDB:HIT000064742"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2090
/gene="hROAT1"
CDS 245..1897
/gene="hROAT1"
/codon_start=1
/product="putative renal organic anion transporter 1"
/protein_id="AAC70004.1"
/translation="MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAI
PTHHCRPPADANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGAT
EPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLG
RRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHT
RACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHS
SSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPT
LRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSL
GRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYP
TMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETL
GQPLPDTVQDLESRKGKQTRQQQEHQKYMVPLQASAQEKNGF"
BASE COUNT 413 a 653 c 611 g 413 t
ORIGIN
1 cgaagtgagg agaagctgca agggaaaagg gagggacaga tcagggagac cggggaagaa
61 ggaggagcag ccaaggaggc tgctgtcccc ccacagagca gctcggactc agctcccgga
121 gcaacccagc tgcggaggca acggcagtgc tgctcctcca gcgaaggaca gcaggcaggc
181 agacagacag aggtcctggg actggaaggc ctcagccccc agccactggg ctgggcctgg
241 cccaatggcc tttaatgacc tcctgcagca ggtggggggt gtcggccgct tccagcagat
301 ccaggtcacc ctggtggtcc tccccctgct cctgatggct tctcacaaca ccctgcagaa
361 cttcactgct gccatcccta cccaccactg ccgcccgcct gccgatgcca acctcagcaa
421 gaacgggggg ctggaggtct ggctgccccg ggacaggcag gggcagcctg agtcctgcct
481 ccgcttcacc tccccgcagt ggggactgcc ctttctcaat ggcacagaag ccaatggcac
541 aggggccaca gagccctgca ccgatggctg gatctatgac aacagcacct tcccgtctac
601 catcgtgact gagtgggacc ttgtgtgctc tcacagggcc ctacgccagc tggcccagtc
661 cttgtacatg gtgggggtgc tgctcggagc catggtgttc ggctaccttg cagacaggct
721 aggccgccgg aaggtactca tcttgaacta cctgcagaca gctgtgtcag ggacctgcgc
781 agccttcgca cccaacttcc ccatctactg cgccttccgg ctcctctcgg gcatggctct
841 ggctggcatc tccctcaact gcatgacact gaatgtggag tggatgccca ttcacacacg
901 ggcctgcgtg ggcaccttga ttggctatgt ctacagcctg ggccagttcc tcctggctgg
961 tgtggcctac gctgtgcccc actggcgcca cctgcagcta ctggtctctg cgcctttttt
1021 tgccttcttc atctactcct ggttcttcat tgagtcggcc cgctggcact cctcctccgg
1081 gaggctggac ctcaccctga gggccctgca gagagtcgcc cggatcaatg ggaagcggga
1141 agaaggagcc aaattgagta tggaggtact ccgggccagt ctgcagaagg agctgaccat
1201 gggcaaaggc caggcatcgg ccatggagct gctgcgctgc cccaccctcc gccacctctt
1261 cctctgcctc tccatgctgt ggtttgccac tagctttgca tactatgggc tggtcatgga
1321 cctgcagggc tttggagtca gcatctacct aatccaggtg atctttggtg ctgtggacct
1381 gcctgccaag cttgtgggct tccttgtcat caactccctg ggtcgccggc ctgcccagat
1441 ggctgcactg ctgctggcag gcatctgcat cctgctcaat ggggtgatac cccaggacca
1501 gtccattgtc cgaacctctc ttgctgtgct ggggaagggt tgtctggctg cctccttcaa
1561 ctgcatcttc ctgtatactg gggaactgta tcccacaatg atccggcaga caggcatggg
1621 aatgggcagc accatggccc gagtgggcag catcgtgagc ccactggtga gcatgactgc
1681 cgagctctac ccctccatgc ctctcttcat ctacggtgct gttcctgtgg ccgccagcgc
1741 tgtcactgtc ctcctgccag agaccctggg ccagccactg ccagacacgg tgcaggacct
1801 ggagagcagg aaagggaaac agacgcgaca gcaacaagag caccagaagt atatggtccc
1861 actgcaggcc tcagcacaag agaagaatgg attttgagga ctgagaaggg gccttacaga
1921 accctaaagg gagggaaggt cctacaggtt tccggccacc cacacaagga ggaggaagag
1981 gaaatggtga cccaagtgtg ggggttgtgg ttcaggaaag cattttccca ggggtccacc
2041 tccctttata aaccccacca gaaccacatc attaaaaggt ttgactgcgc
//