LOCUS AF056322 3579 bp mRNA linear HUM 24-JUN-1998
DEFINITION Homo sapiens SP100-HMG nuclear autoantigen (SP100) mRNA, complete
cds.
ACCESSION AF056322
VERSION AF056322.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3579)
AUTHORS Seeler,J.S., Marchio,A., Sitterlin,D., Transy,C. and Dejean,A.
TITLE Interaction of SP100 with HP1 proteins: a link between the
promyelocytic leukemia-associated nuclear bodies and the chromatin
compartment
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (13), 7316-7321 (1998)
PUBMED 9636146
REFERENCE 2 (bases 1 to 3579)
AUTHORS Seeler,J.-S., Marchio,A. and Dejean,A.
TITLE Direct Submission
JOURNAL Submitted (31-MAR-1998) INSERM U.163/U.R.E.G., Institut Pasteur, 28
rue du Dr. Roux, Paris 75015, France
FEATURES Location/Qualifiers
source 1..3579
/db_xref="H-InvDB:HIT000064691"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q37"
/cell_line="ZR-75"
/cell_type="mammary carcinoma"
gene 1..3579
/gene="SP100"
CDS 32..2671
/gene="SP100"
/note="splice variant"
/codon_start=1
/product="SP100-HMG nuclear autoantigen"
/protein_id="AAC39790.1"
/translation="MAGGGGDLSTRRLNECISPVANEMNHLPAHSHDLQRMFTEDQGV
DDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNLVPV
QRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFENVIHDKLPLQESEEE
EREERSGLQLSLEQGTGENSFRSLTWPPSGSPSHAGTTPPENGLSEHPCETEQINAKR
KDTTSDKDDSLGSQQTNEQCAQKAEPTESCEQIAVQVNNGDAGREMPCPLPCDEESPE
AELHNHGIQINSCSVRLVDIKKEKPFSNSKVECQAQARTHHNQASDIIVISSEDSEGS
TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFR
ESFKKRVIGQDHDFSESSEEEAPAEASSGALRSKHGEKAPMTSRSTSTWRIPSRKRRF
SSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTES
SQASDMMDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQ
KKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSELPVTCGEVKGTLYKERFKQG
TSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTR
KKRILESHNNTLVDPCEEHKKKNPDASVKFSEFLKKCSETWKTIFAKEKGKFEDMAKA
DKAHYEREMKTYIPPKGEKKKKFKDPNAPKRPPLAFFLFCSEYRPKIKGEHPGLSIDD
VVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKDIAAYRAKGKPNSAKKRVVKAEKSK
KKKEEEEDEEDEQEEENEEDDDK"
misc_feature 2126..3051
/gene="SP100"
/note="encodes high-mobility group 1 protein (HMG-1)-like
domain which exhibits non-sequence-specific DNA-binding
activity"
3'UTR 2674..3579
/gene="SP100"
/note="contains sequence which is similar to the
carcino-embryonic antigen (CEA) gene on the reverse
strand"
BASE COUNT 1284 a 667 c 794 g 834 t
ORIGIN
1 ctgaggccca cgcagggcct agggtgggaa gatggcaggt gggggcggcg acctgagcac
61 caggaggctg aatgaatgta tttcaccagt agcaaatgag atgaaccatc ttcctgcaca
121 cagccacgat ttgcaaagga tgttcacgga agaccagggt gtagatgaca ggctgctcta
181 tgacattgta ttcaagcact tcaaaagaaa taaggtggag atttcaaatg caataaaaaa
241 gacatttcca ttcctcgagg gcctccgtga tcgtgatctc atcacaaata aaatgtttga
301 agattctcaa gattcttgta gaaacctggt ccctgtacag agagtggtgt acaatgttct
361 tagtgaactg gagaagacat ttaacctgcc agttctggaa gcactgttca gcgatgtcaa
421 catgcaggaa taccccgatt taattcacat ttataaaggc tttgaaaatg taatccatga
481 caaattgcct ctccaagaaa gtgaagaaga agagagggag gagaggtctg gcctccaact
541 aagtcttgaa caaggaactg gtgaaaactc ttttcgaagc ctgacttggc caccttcggg
601 ttccccatct catgctggta caaccccacc tgaaaatgga ctctcagagc acccctgtga
661 aacagaacag ataaatgcaa agagaaaaga tacaaccagt gacaaagatg attcgctagg
721 aagccaacaa acaaatgaac aatgtgctca aaaggctgag ccaacagagt cctgcgaaca
781 aattgctgtc caagtgaata atggggatgc tggaagggag atgccctgcc cgttgccctg
841 tgatgaagaa agcccagagg cagagctaca caaccatgga atccaaatta attcctgttc
901 tgtgcgactg gtggatataa aaaaggaaaa gccattttct aattcaaaag ttgagtgcca
961 agcccaagca agaactcatc ataaccaggc atctgacata atagtcatca gcagtgagga
1021 ctctgaagga tccactgacg ttgatgagcc cttagaagtc ttcatctcag caccgagaag
1081 tgagcctgtg atcaataatg acaacccttt agaatcaaat gatgaaaagg agggccaaga
1141 agccacttgc tcacgacccc agattgtacc agagcccatg gatttcagaa aattatctac
1201 attcagagaa agttttaaga aaagagtgat aggacaagac cacgactttt cagaatccag
1261 tgaggaggag gcgcccgcag aagcctcaag cggggcactg agaagcaagc atggtgagaa
1321 ggctcctatg acttctagaa gtacatctac ttggagaata cccagcagga agagacgttt
1381 cagcagtagt gacttttcag acctgagtaa tggagaagag cttcaggaaa cctgcagctc
1441 atccctaaga agagggtcag gatcacagcc acaagaacct gaaaataaga agtgctcctg
1501 tgtcatgtgt tttccaaaag gtgtgccaag aagccaagaa gcaaggactg aaagtagtca
1561 agcatctgac atgatggata ccatggatgt tgaaaacaat tctactttgg aaaaacacag
1621 tgggaaaaga agaaaaaaga gaaggcatag atctaaagta aatggtctcc aaagagggag
1681 aaagaaagac agacctagaa aacatttaac tctgaataac aaagtccaaa agaaaagatg
1741 gcaacaaaga ggaagaaaag ccaacactag acctttgaaa agaagaagaa aaagaggtcc
1801 aagaattccc aaagatgaaa atattaattt taaacaatct gaacttcctg tgacctgtgg
1861 tgaggtgaag ggcactctat ataaggagcg attcaaacaa ggaacctcaa agaagtgtat
1921 acagagtgag gataaaaagt ggttcactcc cagggaattt gaaattgaag gagaccgcgg
1981 agcatccaag aactggaagc taagtatacg ctgcggtgga tataccctga aagtcctgat
2041 ggagaacaaa tttctgccag aaccaccaag cacaagaaaa aagagaatac tggaatctca
2101 caacaatacc ttagttgacc cttgtgagga gcataagaag aagaacccag atgcttcagt
2161 caagttctca gagtttttaa agaagtgctc agagacatgg aagaccattt ttgctaaaga
2221 gaaaggaaaa tttgaagata tggcaaaggc ggacaaggcc cattatgaaa gagaaatgaa
2281 aacctatatc cctcctaaag gggagaaaaa aaagaagttc aaggatccca atgcacccaa
2341 gaggcctcct ttggcctttt tcctgttctg ctctgagtat cgcccaaaaa tcaaaggaga
2401 acatcctggc ctgtccattg atgatgttgt gaagaaactg gcagggatgt ggaataacac
2461 cgctgcagct gacaagcagt tttatgaaaa gaaggctgca aagctgaagg aaaaatacaa
2521 aaaggatatt gctgcatatc gagctaaagg aaagcctaat tcagcaaaaa agagagttgt
2581 caaggctgaa aaaagcaaga aaaagaagga agaggaagaa gatgaagagg atgaacaaga
2641 ggaggaaaat gaagaagatg atgataaata agttgcttct agtgcagttt ttttcttgtc
2701 tataaagcat ttaagctgcc tgtacacaac tcactccttt taaagaaaaa aacttcaacg
2761 taagactgtg taagatttgt ttttaaaccg tacactgtgt ttttttgtat agttaaccac
2821 taccgaatgt gtcttcagat agccctgtcc tggtggtatt tagccactaa cctttgcctg
2881 gtacagtatg ggggttgtaa attggcatgg aaatttaaag caggttcttg ttagtgcaca
2941 gcacaaatta gttgtatagg aggatggtag ttttttcacc ttcagttgtc tctgatgtag
3001 cttatacaaa acatttgttg ttctgttaac tgaatgccac tctgtaattg caaaaaaaaa
3061 aaacagttgc agctgttttg ttgacattct gaatgcttct aagtaaatac aatttttaaa
3121 aaaccgtatg agggaactgt gtagacaagg taccaggtca gtcttcttcc atgttctatt
3181 agctccacaa agccaatctc aatccctcaa aacaatcttg tcatacttga aaatatgaca
3241 ctctagtcaa agccttggta aaataatcag tgtttccaat ctgtcctgtt acaaaagaaa
3301 cagattatta ttgaacttat gcaaataacc attgtcataa gaatgtttat gaatagtttc
3361 caaattatgg caaattcatg tagagagaga aaagtaactg ttttggtttt gctcacaaaa
3421 gtctacttta cctaagggct gtcagatata agtaacttaa aagaaagaga agttttcttg
3481 acttttgaaa acaaaatatg aaaagaatcg gcaatgtttc aaacaaaaag tcataaaagt
3541 cactttattc ctccatcaaa aaaaaaaaaa aaaaaaaaa
//