LOCUS AF052692 3617 bp mRNA linear HUM 02-FEB-1999
DEFINITION Homo sapiens connexin 31 (GJB3) mRNA, complete cds.
ACCESSION AF052692
VERSION AF052692.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3617)
AUTHORS Xia,J.H., Liu,C.Y., Tang,B.S., Pan,Q., Huang,L., Dai,H.P.,
Zhang,B.R., Xie,W., Hu,D.X., Zheng,D., Shi,X.L., Wang,D.A., Xia,K.,
Yu,K.P., Liao,X.D., Feng,Y., Yang,Y.F., Xiao,J.Y., Xie,D.H. and
Huang,J.Z.
TITLE Mutations in the gene encoding gap junction protein beta-3
associated with autosomal dominant hearing impairment
JOURNAL Nat. Genet. 20 (4), 370-373 (1998)
PUBMED 9843210
REFERENCE 2 (bases 1 to 3617)
AUTHORS Xia,J.-h., Pan,Q., Liu,C.-y., Zheng,D. and Xie,W.
TITLE Molecular Cloning of Human Connexin 31 and 31.1 Genes
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 3617)
AUTHORS Xia,J.-h., Pan,Q., Liu,C.-y., Zheng,D. and Xie,W.
TITLE Direct Submission
JOURNAL Submitted (08-MAR-1998) National Lab of Medical Genetics of China,
Hunan Medical University, 88 Xiangya Road, Changsha, Hunan 410078,
P. R. China
REFERENCE 4 (bases 1 to 3617)
AUTHORS Xia,J.-h., Pan,Q., Liu,C.-y., Zheng,D. and Xie,W.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-1998) National Lab of Medical Genetics of China,
Hunan Medical University, 88 Xiangya Road, Changsha, Hunan 410078,
P. R. China
REMARK Sequence update by submitter
REFERENCE 5 (bases 1 to 3617)
AUTHORS Xia,J.-h., Pan,Q., Liu,C.-y., Zheng,D. and Xie,W.
TITLE Direct Submission
JOURNAL Submitted (02-FEB-1999) National Lab of Medical Genetics of China,
Hunan Medical University, 88 Xiangya Road, Changsha, Hunan 410078,
P. R. China
REMARK Sequence update by submitter
COMMENT On Feb 2, 1999 this sequence version replaced gi:4001822.
FEATURES Location/Qualifiers
source 1..3617
/db_xref="H-InvDB:HIT000064430"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3617
/gene="GJB3"
CDS 1134..1946
/gene="GJB3"
/note="gap junctional protein cx31"
/codon_start=1
/product="connexin 31"
/protein_id="AAD11816.1"
/translation="MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVW
GDEQKDFDCNTKQPGCTNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERE
RRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPR
LVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGL
HKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPI"
BASE COUNT 859 a 1030 c 936 g 789 t
ORIGIN
1 ggtggcctcg caggcatcac gcatgctcag aggtgcaagt cagctccagg gggactcaca
61 tgcacatagg cccacacaca cacgtggaca ggcaggcggg tgctctcaca cccacagcag
121 cacagaaaca aggcacactc aggcagaccc acccgtccac accctctgag tcactccagg
181 actgggagga agatgtgtga gttaaggcct gaacaaagca catctttcca ccacaaggcc
241 ctggcaacta gtgtggctgg gggtggctgg gcttccccag gcccagcaca gggagcaggg
301 agttttctct agatattccc tggatctagt gtcctcccag gagtcagatc ataaggctcc
361 atgcaccccc cacctgaact ggtctcccct cttcaccacc cagcagctgt gagaccttga
421 gctggttatt tctcctctct gagcctcagt ttccctgctg tagaatggga ctcataactg
481 caacttcaca gtatagtagt gaggcatcca caaagtaaac gtttcaagaa tctggtctag
541 ggcaggagtc cagcggagaa gggaagagga ggtggtggag agcacaggct ctggtaccca
601 acagcctggc cttgaatcca cctcttgttt taagtgagtg acttgacctc tctaaatttc
661 acagtaatga gtagccagca tttatggggc acttactatg tactacttgc tttgcaatcg
721 ttcaatgatc agtttcatct gtaagtgagg agcactgtaa taactacctt atggggtcat
781 tctaagagat taaatgaggt tctgctcata aagtgtttaa cttcatgcct gactctgagt
841 aaacactcaa taaatggtga ttgttattat cagccaaagc atatttgctt ccttccagca
901 tactagctct gttgcctttg gttaagttat ataaccttgc tgtgcctcag tttcctatct
961 gcagcttggg aggaataaca gttctgaact cagagggtcg ttgtgagtat tgaacaagtc
1021 agaactcaga acactgcctg gtacatagta aatgctcaat aaagtcacct attcattcat
1081 acgatggttt ttcctctaat tctcgcaggt aggcacggcc cccaccaggc gccatggact
1141 ggaagacact ccaggcccta ctgagcggtg tgaacaagta ctccacagcg ttcgggcgca
1201 tctggctgtc cgtggtgttc gtcttccggg tgctggtata cgtggtggct gcagagcgcg
1261 tgtgggggga tgagcagaag gactttgact gcaacaccaa gcagcccggc tgcaccaacg
1321 tctgctacga caactacttc cccatctcca acatccgcct ctgggccctg cagctcatct
1381 tcgtcacatg cccctcgctg ctggtcatcc tgcacgtggc ctaccgtgag gagcgggagc
1441 gccggcaccg ccagaaacac ggggaccagt gcgccaagct gtacgacaac gcaggcaaga
1501 agcacggagg cctgtggtgg acctacctgt tcagcctcat cttcaagctc atcattgagt
1561 tcctcttcct ctacctgctg cacactctct ggcatggctt caatatgccg cgcctggtgc
1621 agtgtgccaa cgtggccccc tgccccaaca tcgtggactg ctacattgcc cgacctaccg
1681 agaagaaaat cttcacctac ttcatggtgg gcgcctccgc cgtctgcatc gtactcacca
1741 tctgtgagct ctgctacctc atctgccaca gggtcctgcg aggcctgcac aaggacaagc
1801 ctcgaggggg ttgcagcccc tcgtcctccg ccagccgagc ttccacctgc cgctgccacc
1861 acaagctggt ggaggctggg gaggtggatc cagacccagg caataacaag ctgcaggctt
1921 cagcacccaa cctgaccccc atctgaccac agggcagggg tggggcaaca tgcgggctgc
1981 caatgggaaa tgcagggcag tgtggcaggt ggagaggtcc tacaggggct gagtgacccc
2041 actctgagtt cactaagtta tgcaactttc gttttggcag atattttttg acactgggaa
2101 ctgggctgtc tagccgggta taggtaaccc acaggcccag tgccaccctc aaaggacata
2161 gactttgaaa caagcgaatt aactatctac gctgcctgca aggggccact tagggcactg
2221 ctagcagggc ttcaaccagg aagggatcaa cccaggaagg gatgatcagg agaggcttcc
2281 ctgaggacat aatgtgtaag aaaggtgaga agtgctccca agcagacaca acagcagcac
2341 agaggtctgg aggccacaca aaaagtgatg ctcgccctgg gctagcctca gcagacctaa
2401 ggcatctcta ctccctccag aggagccgcc cagattcttg cagtggagag gaggtcttcc
2461 agcagcagca ggtctggagg gctgagaatg aacctgacta gaggttctgg agatacccag
2521 aggtccccca ggtcatcact tggctcagtg gaagccctct ttccccaaat cctactccct
2581 cagcctcagg cagtggtgct cccatcttcc tccccacaac tgtgctcagg ctggtgccag
2641 cctttcagac cctgctccca gggacttggg tggatgcgct gatagaacat cctcaagaca
2701 gtttccttga aatcaataaa tactgtgttt tatacaggtt ggctctgtct ctggttctcc
2761 cacactccca cccactgaca gaaccctgaa ggtagggaaa ggtaagccct cagaaaggga
2821 aagagttcca tggctcgggg tggagctagg gtgggggctg tggctgtggc tgcagctggg
2881 gcttgagctg gagctcggtt aggctggggc tgatgttgac agccgggagc tgggtttgta
2941 ccagaggagg aggctggggt ggaacctatn nntacatatg ttgggattct agctgtggcc
3001 acaagagtgc gctgtgctcc ctctgcaacg gtgcttccag ccttcgtaat tagacttcac
3061 cctgagtaca cacacaatca ctgccactct cactatagac aaaccacact ccctcctctg
3121 tcacccagtc actgccatct caacacacat ccccaccctg tgtacacaca atctctgtta
3181 ttcatactct cactccttat gcgcactctc aacagggcat gtagtctgca ctcaagcatg
3241 ccatcccagc ctcaccctgc attttattcg gctcatccca ttttccctga acattttcgc
3301 tgaactaggg ccctggcagg atgctgggac tgtgcaagga ggtaggacct atgcccacgg
3361 agctaagaga caggaacaca ggctcatctc ccgcactaac caacccctgg gatggctcac
3421 agcctgctcc cagtgctgtg tcatgacctg aaatttaggg gacaccaaca cccaaggcca
3481 gacccaaatg gaaagcaaaa gaggatgcaa ggctatatta acccagtgga acacttagtg
3541 actatcacag ccgaggccgg gagtcagaaa ttcaggagcc agtgagccaa gcgccacagc
3601 cagcaaagac aggtggg
//