LOCUS AF051894 1244 bp mRNA linear HUM 26-OCT-2000
DEFINITION Homo sapiens 15 kDa selenoprotein mRNA, complete cds.
ACCESSION AF051894
VERSION AF051894.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1244)
AUTHORS Gladyshev,V.N., Jeang,K.T., Wootton,J.C. and Hatfield,D.L.
TITLE A new human selenium-containing protein. Purification,
characterization, and cDNA sequence
JOURNAL J. Biol. Chem. 273 (15), 8910-8915 (1998)
PUBMED 9535873
REFERENCE 2 (bases 1 to 1244)
AUTHORS Gladyshev,V.N., Jeang,K.-T., Wootton,J.C. and Hatfield,D.L.
TITLE Direct Submission
JOURNAL Submitted (28-FEB-1998) Department of Biochemistry, University of
Nebraska, Lincoln, NE 68588, USA
FEATURES Location/Qualifiers
source 1..1244
/db_xref="H-InvDB:HIT000064274"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31"
CDS 5..493
/codon_start=1
/transl_except=(pos:281..283,aa:Sec)
/product="15 kDa selenoprotein"
/protein_id="AAC15478.1"
/translation="MAAGPSGCLVPAFGLRLLLATVLQAVSAFGAEFSSEACRELGFS
SNLLCSSCDLLGQFNLLQLDPDCRGCCQEEAQFETKKLYAGAILEVCGUKLGRFPQVQ
AFVRSDKPKLFRGLQIKYVRGSDPVLKLLDDNGNIAEELSILKWNTDSVEEFLSEKLE
RI"
misc_feature 1083..1164
/note="SECIS element; causes positions 281..283 (TGA) to
be translated as selenocysteine"
BASE COUNT 380 a 217 c 257 g 390 t
ORIGIN
1 agcgatggcg gctgggccga gtgggtgtct ggtgccggcg tttgggctac ggttgttgtt
61 ggcgactgtg cttcaagcgg tgtctgcttt tggggcagag ttttcatcgg aggcatgcag
121 agagttaggc ttttctagca acttgctttg cagctcttgt gatcttctcg gacagttcaa
181 cctgcttcag ctggatcctg attgcagagg atgctgtcag gaggaagcac aatttgaaac
241 caaaaagctg tatgcaggag ctattcttga agtttgtgga tgaaaattgg gaaggttccc
301 tcaagtccaa gcttttgtta ggagtgataa acccaaactg ttcagaggac tgcaaatcaa
361 gtatgtccgt ggttcagacc ctgtattaaa gcttttggac gacaatggga acattgctga
421 agaactgagc attctcaaat ggaacacaga cagtgtagaa gaattcctga gtgaaaagtt
481 ggaacgcata taaatcttgc ttaaattttg tcctatcctt ttgttacctt atcaaatgaa
541 atattacagc acctagaaaa taatttagtt ttgcttgctt ccattgatca gtcttttact
601 tgaggcatta aatatctaat taaatcgtga aatggcagta tagtccatga tatctaagga
661 gttggcaagc ttaacaaaac ccatttttta taaatgtcca tcctcctgca tttgttgata
721 ccactaacaa aatgctttgt aacagacttg cggttaatta tgcaaatgat agtttgtgat
781 aattggtcca gttttacgaa caacagattt ctaaattaga gaggttaaca agacagatga
841 ttactatgcc tcatgtgctg tgtgctcttt gaaaggaatg acagcagact acaaagcaaa
901 taagatatac tgagcctcaa cagattgcct gctcctcaga gtctctccta tttttgtatt
961 acccagcttt ctttttaata caaatgttat ttatagttta caatgaatgc actgcataaa
1021 aactttgtag cttcattatt gtaaaacata ttcaagatcc tacagtaaga gtgaaacatt
1081 cacaaagatt tgcgttaatg aagactacac agaaaacctt tctagggatt tgtgtggatc
1141 agatacatac ttggcaaatt tttgagtttt acattcttac agaaaagtcc atttaaaagt
1201 gatcatttgt aagaccaaaa tataaataaa aagtttcaaa aatc
//