LOCUS AF051426 2144 bp mRNA linear HUM 16-MAR-1998
DEFINITION Homo sapiens slow delayed rectifier channel subunit mRNA, complete
cds.
ACCESSION AF051426
VERSION AF051426.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2144)
AUTHORS Jiang,M., Tseng-Crank,J. and Tseng,G.N.
TITLE Suppression of slow delayed rectifier current by a truncated
isoform of KvLQT1 cloned from normal human heart
JOURNAL J. Biol. Chem. 272 (39), 24109-24112 (1997)
PUBMED 9305853
REFERENCE 2 (bases 1 to 2144)
AUTHORS Jiang,M., Tseng-Crank,J. and Tseng,G.-N.
TITLE Direct Submission
JOURNAL Submitted (27-FEB-1998) Pharmacology, Columbia University, 630 W.
168th Street, New York, NY 10032, USA
FEATURES Location/Qualifiers
source 1..2144
/db_xref="H-InvDB:HIT000064262"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="heart"
/clone_lib="CLONTECH Marathon Ready cDNA, Catalog Number
7404-1; Lot Number 6050943"
/note="normal tissue"
CDS 257..1903
/note="tKvLQT1; truncated form of KvLQT1; nonfunctional
alone but modulatory when coexpressed with the full-length
KvLQT1 isoform"
/codon_start=1
/product="slow delayed rectifier channel subunit"
/protein_id="AAC05705.1"
/translation="MDFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEY
VVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRG
IRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDA
VNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAG
ILGSGFALKVQQKQRQKHFNRQIPAASLIQTAWRCYAAENPDSSTWKIYIRKAPRSHT
LLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYD
SSVRKSPTLLEVSMPHFMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRM
QYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSE
KSKDRGSNTIGARLNRVEDKVTQLDQRLALITDMLHQLLSLHGGSTPGSGGPPREGGA
HITQPCGSGGSVDPELFLPSNTLPTYEQLTVPRRGPDEGS"
BASE COUNT 410 a 670 c 652 g 412 t
ORIGIN
1 gcagcttcca tggcctgggg ctgtgagagg cccgggaagg cactgtcttt gcgcctgcac
61 atgtgtgtgt ctggagtgta ggatggcact ggtgccgggc ctggatttac tcagcccaga
121 tcacggctgc ttttgtttac gtggcccctg ctctcaccca caactccagg tttctggctc
181 tcgggaattt gaggcctgtg gctgctgtgg accctgggaa agagcctgtg cttcctgagc
241 cagtgcgggg cctggcatgg acttcctcat cgtcctggtc tgcctcatct tcagcgtgct
301 gtccaccatc gagcagtatg ccgccctggc cacggggact ctcttctgga tggagatcgt
361 gctggtggtg ttcttcggga cggagtacgt ggtccgcctc tggtccgccg gctgccgcag
421 caagtacgtg ggcctctggg ggcggctgcg ctttgcccgg aagcccattt ccatcatcga
481 cctcatcgtg gtcgtggcct ccatggtggt cctctgcgtg ggctccaagg ggcaggtgtt
541 tgccacgtcg gccatcaggg gcatccgctt cctgcagatc ctgaggatgc tacacgtcga
601 ccgccaggga ggcacctgga ggctcctggg ctccgtggtc ttcatccacc gccaggagct
661 gataaccacc ctgtacatcg gcttcctggg cctcatcttc tcctcgtact ttgtgtacct
721 ggctgagaag gacgcggtga acgagtcagg ccgcgtggag ttcggcagct acgcagatgc
781 gctgtggtgg ggggtggtca cagtcaccac catcggctat ggggacaagg tgccccagac
841 gtgggtcggg aagaccatcg cctcctgctt ctctgtcttt gccatctcct tctttgcgct
901 cccagcgggg attcttggct cggggtttgc cctgaaggtg cagcagaagc agaggcagaa
961 gcacttcaac cggcagatcc cggcggcctc actcattcag accgcatgga ggtgctatgc
1021 tgccgagaac cccgactcct ccacctggaa gatctacatc cggaaggccc cccggagcca
1081 cactctgctg tcacccagcc ccaaacccaa gaagtctgtg gtggtaaaga aaaaaaagtt
1141 caagctggac aaagacaatg gggtgactcc tggagagaag atgctcacag tcccccatat
1201 cacgtgcgac cccccagaag agcggcggct ggaccacttc tctgtcgacg gctatgacag
1261 ttctgtaagg aagagcccaa cactgctgga agtgagcatg ccccatttca tgagaaccaa
1321 cagcttcgcc gaggacctgg acctggaagg ggagactctg ctgacaccca tcacccacat
1381 ctcacagctg cgggaacacc atcgggccac cattaaggtc attcgacgca tgcagtactt
1441 tgtggccaag aagaaattcc agcaagcgcg gaagccttac gatgtgcggg acgtcattga
1501 gcagtactcg cagggccacc tcaacctcat ggtgcgcatc aaggagctgc agaggaggct
1561 ggaccagtcc attgggaagc cctcactgtt catctccgtc tcagaaaaga gcaaggatcg
1621 cggcagcaac acgatcggcg cccgcctgaa ccgagtagaa gacaaggtga cgcagctgga
1681 ccagaggctg gcactcatca ccgacatgct tcaccagctg ctctccttgc acggtggcag
1741 cacccccggc agcggcggcc cccccagaga gggcggggcc cacatcaccc agccctgcgg
1801 cagtggcggc tccgtcgacc ctgagctctt cctgcccagc aacaccctgc ccacctacga
1861 gcagctgacc gtgcccagga ggggccccga tgaggggtcc tgaggagggg atggggctgg
1921 gggatgggcc tgagtgagag gggaggccaa gagtggcccc acctggccct ctctgaagga
1981 ggccacctcc taaaaggccc agagagaaga gccccactct cagaggcccc aataccccat
2041 ggaccatgct gtctggcaca gcctgcactt gggggctcag caaggccacc tcttcctggc
2101 cggtgtgggg gccccgtctc aggtctgagt tgttacccgg atcc
//